Quiz
Pharmacology VI
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Questions in this quiz (40)
1Quinidine is principally used to treat
- Aa. Hypertension
- Bb. Angina pectoris
- Cc. Congestive hear failure
- Dd. Supraventricular tachyarrhythmias
2Quinidine is used to treat
- Aa. Hypertension
- Bb. Angina pectoris
- Cc. Atrial fibrillation
- Dd. Ventricular fibrillation
- Ee. Congestive hear failure
3Verapamil is most efficacious in the treatment of
- Aa. Atrial fibrillation
- Bb. Atrial tachycardia
- Cc. Ventricular tachycardia
- Dd. Catecholamine-induced arrhythmias
4Which of the following drugs is most useful in treating or preventing angina pectoris?
- Aa. Digitalis
- Bb. Quinidine
- Cc. Propranolol
- Dd. Procainamide
- Ee. Pentobarbital
5Each of the following drugs can be used in the prevention and treatment of angina pectoris EXCEPT
- Aa. Digitalis
- Bb. Propranolol
- Cc. Nitroglycerin
- Dd. Isosorbide dinitrate
- Ee. Pentaerythritol tetranitrate
6All of the following drugs are useful in the treatment of hypertension EXCEPT
- Aa. Ephedrine
- Bb. Reserpine
- Cc. Methyldopa
- Dd. Thiazide diuretics
7Digitalis is useful in the treatment of which of the following conditions?
- Aa. Atrial fibrillation
- Bb. Congestive heart failure
- Cc. Paroxysmal atrial tachycardia
- Dd. All of the above
8All of the following drugs are useful in the treatment of cardiac arrhythmias EXCEPT
- Aa. Digitalis
- Bb. Lidocaine
- Cc. Phenytoin
- Dd. Procainamide
- Ee. Aminophylline
9The drug of choice for initial therapy for mild hypertension is
- Aa. Reserpine
- Bb. Guanethidine
- Cc. Phenobarbital
- Dd. Chlorothiazide
- Ee. Alpha-methyldopa
10Which of the following antihypertensives are usually reserved for treatment of severe hypertension?
- Aa. Sedatives and reserpine
- Bb. Thiazide diuretics and reserpine
- Cc. Sedatives and thiazide diuretics
- Dd. Guanethidine and ganglionic blocking agents
11Which of the following beta-adrenergic receptor blocking agents is thought to be cardioselective?
- Aa. Nadolol
- Bb. Timolol
- Cc. Metoprolol
- Dd. Propranolol
12Antiarrhythmic drugs, such as quinidine, suppress certain cardiac arrhythmias by
- Aa. Stimulating the beta-adrenergic receptor
- Bb. Suppressing cardiac ATP-ase activity
- Cc. Increasing ectopic pacemaker activity
- Dd. Increasing the refractory period of cardiac muscle
13Most drugs useful in the treatment of cardiac arrhythmias act primarily by
- Aa. Blocking Purkinje fibers
- Bb. Blocking the alpha-adrenergic receptor
- Cc. Suppressing SA node impulse formation
- Dd. Causing a positive inotropic effect
- Ee. Increasing the refractory period of cardiac muscle
14The most important pharmacologic action of drugs that suppress cardiac arrhythmias is
- Aa. Blockade of the vagus nerve
- Bb. Stimulation of cardiac ATP-ase activity
- Cc. Blockade of the Beta-adrenergic receptor
- Dd. Stimulation of the beta-adrenergic receptor
- Ee. Increased refractory period of cardiac muscle
15Lidocaine produces its antiarrhythmic effects by
- Aa. Increasing AV conduction
- Bb. Decreasing cardiac excitability
- Cc. Increasing cardiac conduction velocity
- Dd. Increasing spontaneous pacemaker activity
16When digitalis is used in atrial fibrillation, the therapeutic objective is to
- Aa. Abolish cardiac decompensation
- Bb. Inhibit vagal impulses to the heart
- Cc. Decrease the rate of A-V conduction
- Dd. Increase the rate of cardiac repolarization
- Ee. Produce a decrease in the rate of atrial contraction
17Nitroglycerin dilates the coronary arteries in angina pectoris by
- Aa. Decreasing the heart rate reflexly
- Bb. Increasing the metabolic work of the myocardium
- Cc. Direct action on smooth muscle in the vessel walls
- Dd. Increasing the effective refractory period in the atrium
- Ee. Blocking beta-adrenergic receptors
18Propranolol is of value in treating angina pectoris because it
- Aa. Has a direct action on vascular smooth muscle
- Bb. Blocks autoregulatory mechanisms in the heart
- Cc. Inhibits oxygen metabolism in cardiac cells
- Dd. Provides relief within seconds of an acute anginal attack
- Ee. Prevents chronotropic responses to endogenous epinephrine emotions and exercise
19Administration of angiotensin results in
- Aa. Anti-inflammatory effects
- Bb. Antihistaminic effects
- Cc. Increased blood pressure
- Dd. Increased heart rate
- Ee. A sedative effect
20The primary antihypertensive effect of captopril (Capoten) is due to accumulation of
- Aa. Serotonin
- Bb. Angiotensin I
- Cc. Angiotensin III
- Dd. Bradykinin metabolites
21Administration of angiotensin results in
- Aa. A sedative effect
- Bb. Increased heart rate
- Cc. Increased blood pressure
- Dd. Antihistaminic effects
- Ee. Anti-inflammatory effects
22Which of the following is NOT characteristic of the thiazide diuretics?
- Aa. Increase renal excretion of sodium and chloride
- Bb. Increase renal excretion of potassium
- Cc. Increase the toxicity of digitalis
- Dd. Exacerbate existing diabetes
- Ee. Cause hypokalemia
- Ff. Cause hypoglycemia
23The most useful diuretic drugs act by
- Aa. Increasing the glomerular filtration rate
- Bb. Decreasing the renal reabsorption of sodium
- Cc. Decreasing the renal excretion of chloride
- Dd. Increasing the renal reabsorption of potassium
- Ee. Increasing the secretion of antidiuretic hormone
24Which of the following drugs act by inhibiting renal reabsorption of sodium?
- Aa. Urea
- Bb. Chlorothiazide
- Cc. Theophylline
- Dd. digitalis glycosides
- Ee. Procainamide
25Digoxin exerts its positive inotropic effect by
- Aa. Activation of adenylcyclase
- Bb. Inhibition of phosphodiesterase
- Cc. An agonist effect of beta-receptors
- Dd. Inhibition of Na+, K+ ATPASE leading to increased calcium influx
- Ee. Decreasing the amount of calcium available for excitationcontraction coupling
26Digitoxin is effective in the treatment of cardiac failure because it
- Aa. Is primarily a diuretic
- Bb. Reduces the ventricular rate
- Cc. Decreases abnormal cardiac rhythms
- Dd. Produces peripheral vasoconstriction
- Ee. Has a positive cardiac inotropic action
27The primary action of therapeutic doses of digitalis on cardiac muscle is an increase in
- Aa. Force of contraction
- Bb. Ventricular excitability
- Cc. Refractory period of the atrial muscle
- Dd. Refractory period of the ventricular muscle
- Ee. Rate of conduction of impulse to the muscle
28The beneficial effects of digitalis in congestive heart failure result in part from the fact that digitalis causes
a. A decrease in end-diastolic volume
b. A decrease in end-diastolic pressure
c. An increase in stroke volume and cardiac output
d. A decrease in central venous pressure
e. A decrease in rate of the hear where tachycardia exists- Aa) (a), (b) and (c)
- Bb) (a) and (c) only
- Cc) (c) and (d)
- Dd) (e) only
- Ee) All of the above
29The cardiac glycosides will increase the concentration of which ion in an active heart muscle?
- Aa. Sodium
- Bb. Bromide
- Cc. Calcium
- Dd. Chloride
- Ee. Potassium
30Which of the following ions augments the inotropic effect of digitalis?
- Aa. Sodium
- Bb. Lithium
- Cc. Calcium
- Dd. Chloride
- Ee. Magnesium
31In the treatment of congestive heart failure, digitalis glycosides generally decrease all of the following EXCEPT
- Aa. Edema
- Bb. Urine flow
- Cc. Heart size
- Dd. Heart rate
- Ee. Residual diastolic volume
32The mechanism of action of prazosin, an antihypertensive agent is to
- Aa. Block beta-adrenergic receptors
- Bb. Inhibit formation of angiotensin II
- Cc. Inhibit nerve-induced release of norepinephrine
- Dd. Stimulate central inhibitory alpha-adrenergic receptors
- Ee. Inhibit the postsynaptic of norepinephrine on vascular smooth muscle
33Which of the following owes a significant amount of its antihypertensive effect to a central action?
- Aa. Methyldopa
- Bb. Metoprolol
- Cc. Hydralazine
- Dd. Propranolol
- Ee. Guanethidine
34Which of the following drugs is thought to reduce arterial blood pressure by activating alpha receptors in the vasomotor center of the medulla?
- Aa. Prazosin
- Bb. Clonidine
- Cc. Propranolol
- Dd. Guanethidine
- Ee. Chlorothiazide
35Propranolol (Inderal) can be useful in the treatment of hypertension because it blocks
- Aa) (a) and (b)
- Bb) (a) and (d)
- Cc) (b), (c) and (d)
- Dd) (c), (d) and (e)
- Ee) (c) and (e) only
36One of the proposed mechanisms of the antihypertensive effect of beta-adrenergic receptor blocking agents is
- Aa. Sedation
- Bb. A diuretic effect
- Cc. An antirenin effect
- Dd. A vagal blocking effect
- Ee. An increase in cardiac output
37Selective beta-1 adrenergic agonists will produce which of the following effects?
- Aa. Glycogenolysis
- Bb. Increased cardiac output
- Cc. Decreased diastolic pressure
- Dd. Decreased peripheral resistance
- Ee. Relaxation of bronchial smooth muscle
38Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
- Aa. Osmotic
- Bb. Thiazide
- Cc. Mercurial
- Dd. High-ceiling
39Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
- Aa. Osmotic
- Bb. Thiazide
- Cc. Mercurial
- Dd. High-ceiling
40Symptoms of digitalis toxicity include all of the following EXCEPT
- Aa. Extrasystoles
- Bb. Nausea and vomiting
- Cc. Yellow-green vision
- Dd. A-V conduction block
- Ed. Chlorothiazide
- Fe. Acetylsalicylic acid
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- Praxis Tests: Pharmacology Quiz on Pharmacology VI, created by ACAPUN INSTITUTE on 08/11/2021.
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