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Pharmacology VI

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Praxis Tests: Pharmacology Quiz on Pharmacology VI, created by ACAPUN INSTITUTE on 08/11/2021.
ACAPUN INSTITUTE
Quiz by ACAPUN INSTITUTE, updated more than 1 year ago
ACAPUN INSTITUTE
Created by ACAPUN INSTITUTE over 2 years ago
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Question 1

Question
Quinidine is principally used to treat
Answer
  • a. Hypertension
  • b. Angina pectoris
  • c. Congestive hear failure
  • d. Supraventricular tachyarrhythmias

Question 2

Question
Quinidine is used to treat
Answer
  • a. Hypertension
  • b. Angina pectoris
  • c. Atrial fibrillation
  • d. Ventricular fibrillation
  • e. Congestive hear failure

Question 3

Question
Verapamil is most efficacious in the treatment of
Answer
  • a. Atrial fibrillation
  • b. Atrial tachycardia
  • c. Ventricular tachycardia
  • d. Catecholamine-induced arrhythmias

Question 4

Question
Which of the following drugs is most useful in treating or preventing angina pectoris?
Answer
  • a. Digitalis
  • b. Quinidine
  • c. Propranolol
  • d. Procainamide
  • e. Pentobarbital

Question 5

Question
Each of the following drugs can be used in the prevention and treatment of angina pectoris EXCEPT
Answer
  • a. Digitalis
  • b. Propranolol
  • c. Nitroglycerin
  • d. Isosorbide dinitrate
  • e. Pentaerythritol tetranitrate

Question 6

Question
All of the following drugs are useful in the treatment of hypertension EXCEPT
Answer
  • a. Ephedrine
  • b. Reserpine
  • c. Methyldopa
  • d. Thiazide diuretics

Question 7

Question
Digitalis is useful in the treatment of which of the following conditions?
Answer
  • a. Atrial fibrillation
  • b. Congestive heart failure
  • c. Paroxysmal atrial tachycardia
  • d. All of the above

Question 8

Question
All of the following drugs are useful in the treatment of cardiac arrhythmias EXCEPT
Answer
  • a. Digitalis
  • b. Lidocaine
  • c. Phenytoin
  • d. Procainamide
  • e. Aminophylline

Question 9

Question
The drug of choice for initial therapy for mild hypertension is
Answer
  • a. Reserpine
  • b. Guanethidine
  • c. Phenobarbital
  • d. Chlorothiazide
  • e. Alpha-methyldopa

Question 10

Question
Which of the following antihypertensives are usually reserved for treatment of severe hypertension?
Answer
  • a. Sedatives and reserpine
  • b. Thiazide diuretics and reserpine
  • c. Sedatives and thiazide diuretics
  • d. Guanethidine and ganglionic blocking agents

Question 11

Question
Which of the following beta-adrenergic receptor blocking agents is thought to be cardioselective?
Answer
  • a. Nadolol
  • b. Timolol
  • c. Metoprolol
  • d. Propranolol

Question 12

Question
Antiarrhythmic drugs, such as quinidine, suppress certain cardiac arrhythmias by
Answer
  • a. Stimulating the beta-adrenergic receptor
  • b. Suppressing cardiac ATP-ase activity
  • c. Increasing ectopic pacemaker activity
  • d. Increasing the refractory period of cardiac muscle

Question 13

Question
Most drugs useful in the treatment of cardiac arrhythmias act primarily by
Answer
  • a. Blocking Purkinje fibers
  • b. Blocking the alpha-adrenergic receptor
  • c. Suppressing SA node impulse formation
  • d. Causing a positive inotropic effect
  • e. Increasing the refractory period of cardiac muscle

Question 14

Question
The most important pharmacologic action of drugs that suppress cardiac arrhythmias is
Answer
  • a. Blockade of the vagus nerve
  • b. Stimulation of cardiac ATP-ase activity
  • c. Blockade of the Beta-adrenergic receptor
  • d. Stimulation of the beta-adrenergic receptor
  • e. Increased refractory period of cardiac muscle

Question 15

Question
Lidocaine produces its antiarrhythmic effects by
Answer
  • a. Increasing AV conduction
  • b. Decreasing cardiac excitability
  • c. Increasing cardiac conduction velocity
  • d. Increasing spontaneous pacemaker activity

Question 16

Question
When digitalis is used in atrial fibrillation, the therapeutic objective is to
Answer
  • a. Abolish cardiac decompensation
  • b. Inhibit vagal impulses to the heart
  • c. Decrease the rate of A-V conduction
  • d. Increase the rate of cardiac repolarization
  • e. Produce a decrease in the rate of atrial contraction

Question 17

Question
Nitroglycerin dilates the coronary arteries in angina pectoris by
Answer
  • a. Decreasing the heart rate reflexly
  • b. Increasing the metabolic work of the myocardium
  • c. Direct action on smooth muscle in the vessel walls
  • d. Increasing the effective refractory period in the atrium
  • e. Blocking beta-adrenergic receptors

Question 18

Question
Propranolol is of value in treating angina pectoris because it
Answer
  • a. Has a direct action on vascular smooth muscle
  • b. Blocks autoregulatory mechanisms in the heart
  • c. Inhibits oxygen metabolism in cardiac cells
  • d. Provides relief within seconds of an acute anginal attack
  • e. Prevents chronotropic responses to endogenous epinephrine emotions and exercise

Question 19

Question
Administration of angiotensin results in
Answer
  • a. Anti-inflammatory effects
  • b. Antihistaminic effects
  • c. Increased blood pressure
  • d. Increased heart rate
  • e. A sedative effect

Question 20

Question
The primary antihypertensive effect of captopril (Capoten) is due to accumulation of
Answer
  • a. Serotonin
  • b. Angiotensin I
  • c. Angiotensin III
  • d. Bradykinin metabolites

Question 21

Question
Administration of angiotensin results in
Answer
  • a. A sedative effect
  • b. Increased heart rate
  • c. Increased blood pressure
  • d. Antihistaminic effects
  • e. Anti-inflammatory effects

Question 22

Question
Which of the following is NOT characteristic of the thiazide diuretics?
Answer
  • a. Increase renal excretion of sodium and chloride
  • b. Increase renal excretion of potassium
  • c. Increase the toxicity of digitalis
  • d. Exacerbate existing diabetes
  • e. Cause hypokalemia
  • f. Cause hypoglycemia

Question 23

Question
The most useful diuretic drugs act by
Answer
  • a. Increasing the glomerular filtration rate
  • b. Decreasing the renal reabsorption of sodium
  • c. Decreasing the renal excretion of chloride
  • d. Increasing the renal reabsorption of potassium
  • e. Increasing the secretion of antidiuretic hormone

Question 24

Question
Which of the following drugs act by inhibiting renal reabsorption of sodium?
Answer
  • a. Urea
  • b. Chlorothiazide
  • c. Theophylline
  • d. digitalis glycosides
  • e. Procainamide

Question 25

Question
Digoxin exerts its positive inotropic effect by
Answer
  • a. Activation of adenylcyclase
  • b. Inhibition of phosphodiesterase
  • c. An agonist effect of beta-receptors
  • d. Inhibition of Na+, K+ ATPASE leading to increased calcium influx
  • e. Decreasing the amount of calcium available for excitationcontraction coupling

Question 26

Question
Digitoxin is effective in the treatment of cardiac failure because it
Answer
  • a. Is primarily a diuretic
  • b. Reduces the ventricular rate
  • c. Decreases abnormal cardiac rhythms
  • d. Produces peripheral vasoconstriction
  • e. Has a positive cardiac inotropic action

Question 27

Question
The primary action of therapeutic doses of digitalis on cardiac muscle is an increase in
Answer
  • a. Force of contraction
  • b. Ventricular excitability
  • c. Refractory period of the atrial muscle
  • d. Refractory period of the ventricular muscle
  • e. Rate of conduction of impulse to the muscle

Question 28

Question
The beneficial effects of digitalis in congestive heart failure result in part from the fact that digitalis causes a. A decrease in end-diastolic volume b. A decrease in end-diastolic pressure c. An increase in stroke volume and cardiac output d. A decrease in central venous pressure e. A decrease in rate of the hear where tachycardia exists
Answer
  • a) (a), (b) and (c)
  • b) (a) and (c) only
  • c) (c) and (d)
  • d) (e) only
  • e) All of the above

Question 29

Question
The cardiac glycosides will increase the concentration of which ion in an active heart muscle?
Answer
  • a. Sodium
  • b. Bromide
  • c. Calcium
  • d. Chloride
  • e. Potassium

Question 30

Question
Which of the following ions augments the inotropic effect of digitalis?
Answer
  • a. Sodium
  • b. Lithium
  • c. Calcium
  • d. Chloride
  • e. Magnesium

Question 31

Question
In the treatment of congestive heart failure, digitalis glycosides generally decrease all of the following EXCEPT
Answer
  • a. Edema
  • b. Urine flow
  • c. Heart size
  • d. Heart rate
  • e. Residual diastolic volume

Question 32

Question
The mechanism of action of prazosin, an antihypertensive agent is to
Answer
  • a. Block beta-adrenergic receptors
  • b. Inhibit formation of angiotensin II
  • c. Inhibit nerve-induced release of norepinephrine
  • d. Stimulate central inhibitory alpha-adrenergic receptors
  • e. Inhibit the postsynaptic of norepinephrine on vascular smooth muscle

Question 33

Question
Which of the following owes a significant amount of its antihypertensive effect to a central action?
Answer
  • a. Methyldopa
  • b. Metoprolol
  • c. Hydralazine
  • d. Propranolol
  • e. Guanethidine

Question 34

Question
Which of the following drugs is thought to reduce arterial blood pressure by activating alpha receptors in the vasomotor center of the medulla?
Answer
  • a. Prazosin
  • b. Clonidine
  • c. Propranolol
  • d. Guanethidine
  • e. Chlorothiazide

Question 35

Question
Propranolol (Inderal) can be useful in the treatment of hypertension because it blocks
Answer
  • a) (a) and (b)
  • b) (a) and (d)
  • c) (b), (c) and (d)
  • d) (c), (d) and (e)
  • e) (c) and (e) only

Question 36

Question
One of the proposed mechanisms of the antihypertensive effect of beta-adrenergic receptor blocking agents is
Answer
  • a. Sedation
  • b. A diuretic effect
  • c. An antirenin effect
  • d. A vagal blocking effect
  • e. An increase in cardiac output

Question 37

Question
Selective beta-1 adrenergic agonists will produce which of the following effects?
Answer
  • a. Glycogenolysis
  • b. Increased cardiac output
  • c. Decreased diastolic pressure
  • d. Decreased peripheral resistance
  • e. Relaxation of bronchial smooth muscle

Question 38

Question
Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
Answer
  • a. Osmotic
  • b. Thiazide
  • c. Mercurial
  • d. High-ceiling

Question 39

Question
Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
Answer
  • a. Osmotic
  • b. Thiazide
  • c. Mercurial
  • d. High-ceiling

Question 40

Question
Symptoms of digitalis toxicity include all of the following EXCEPT
Answer
  • a. Extrasystoles
  • b. Nausea and vomiting
  • c. Yellow-green vision
  • d. A-V conduction block
  • d. Chlorothiazide
  • e. Acetylsalicylic acid
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