NAFLD

Beschreibung

Mindmap am NAFLD, erstellt von mohammed mansour am 25/02/2018.
mohammed mansour
Mindmap von mohammed mansour, aktualisiert more than 1 year ago
mohammed mansour
Erstellt von mohammed mansour vor etwa 6 Jahre
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Zusammenfassung der Ressource

NAFLD
  1. Anatomy of the liver
    1. Histology of the liver
      1. Lipid Metabolism
        1. A. Transport of acetyl COA into cytosol B. Carboxylation of acetyl COA C. Assembly of FA chain
        2. Nonalcoholic fatty liver disease (NAFLD) is a condition in which excess fat is stored in the liver with the absence of significant alcohol intake.
          1. Risk factors
            1. Obesity, Diabetes Mellitus, Hypertriglyceridemia, Surgery (Jejunoileal Bypass), Medications (Corticosteroids, Estrogens, Amiodarone), Exposures to organic solvents.
            2. Signs & Symptoms
              1. Elevation of serum transaminases, fatigue, malaise, right upper quadrant discomfort.
                1. Most are asymptomatic
                2. Causes
                  1. Metabolic syndrome
                    1. defined as having at least two of the following: obesity, insulin resistance, dyslipidemia, and hypertension
                  2. Investigation
                    1. Waist to hip ratio (WHR)
                      1. Physical examination
                        1. Complete blood count
                          1. Lipid profile
                            1. AST and ALT enzymes
                              1. X-Ray of abdomen
                              2. Complications
                                1. cirrhosis, liver failure,  liver cancer, edema and ascites, hepatic encephalopathy, hepatorenal syndrome, hepatopulmonary syndrome, hypersplenism, bacterial peritonitis.
                                2. Management
                                  1. Pharmacological
                                    1. Orlista, Lorcaserin, phentermine-topiramate, Liraglutide.
                                    2. Bariatric surgery
                                    3. Affected by
                                      1. Types of Diets
                                        1. Atkins Diet
                                          1. Nutrisystem Diet
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