Zusammenfassung der Ressource
Environmental Toxicology 1-3
- focuses on synthetic
and natural pollutants on
ecosystems
- Silent Spring
- Chemical effects on ecosystems (DDT),
- North American environmental movement
- Paracelsus
- Dose makes the poison
- toxicon
- Environmental tragedies
(Safety)
- Minamata, Japan: MeHg
- Kiev, Ukraine: Radioactive dust
- Bhopal, India: Methyl Isocyanate (MIC)
- Toxic Substances
- Xenobiotic
- Poison
- Toxicant
- Toxin
- Efficacy (max)
- Potency (range of increase)
- Interactions
- Additive
- Synergistic
- Antagonistic
- Exposure Tests
- Acute
- Lethal dose
- PROS: estimate toxicity, target organs
- CONS: expensive, animal use, ethics
- Subacute
- Subchronic
- LOAEL and NOAEL
- Chronic
- Best LOAEL and NOAEL
- General Toxicity
- Threshold vs. non-Threshold
- Essential nutrients
- U-shaped (copper)
- Hormesis
- J-shaped (alcohol)
- Placebo
- Nocebo