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What are the function of the following salivary secretions?
1) Amylase
2) Lysozyme
3) Bicarbonate
4) Growth factors
5) Transcobalamin II
What are the functions of the following gastric luminal secretions?
1) Mucus
2) Acid
3) Proteases (pepsin and chymosin/rennin)
4) Lipase
5) Intrinsic factor
Where is intrinsic factor produced? Transcobalamin?
What are/what do the following secrete?
1) Mucous neck cells
2) Parietal cells
3) ECL cells
4) Chief cells
5) G cells
Describe the mechanism which facilitates acid secretion into the lumen.
How do the cells of the gastric pits vary between a quiescent state and digestion?
Describe the pH difference across the gastric mucus gel layer? What is present in the mucous layer? What can increase the solubility of the mucous?
What are the main mechanisms of feedback control of acid secretion?
Describe the effect of activation of the enteric nervous system on gastric secretions.
How do D cells modulate gastric secretions (note the type of signalling)?
How do G cells modulate gastric secretions?
What is Zollinger-Ellison syndrome (ZES)?
How do calcium and prostaglandins affect acid secretion?
Describe the neural control of gastric secretion in the cephalic phase?
What happens in the gastric phase? How is it regulated neuronaly?
How is the gastric phase terminated?
What two substances are responsible for bile production?
What are the actions of CCK and secretin?
What percentage of the world are infected with helicobacter pylori? When does it cause a problem? Where is the infection usually located?
How does H. pylori cause damage?
What are the diagnostic tests for detecting H. Pylori? What is the main treatment?
What are all the different treatments for treating peptic ulcer disease? (3)
How do proton pumps inhibitor drug names end?
What is reflux? What is GORD? How much of the population does it affect? What is it not?
What causes GORD?
How is GORD treated?
What is the surgical option for GORD?
What are the two major active components of gaviscon and what do they do?
