What are electrolytes responsible for?
a. maintain homeostasis
b. maintain body fluid composition
c. maintain body fluid volume
d. carry electrical charges in fluid
e. all the above are correct
Which of the following is an anion?
a. potassium
b. calcium
c. magnesium
d. sodium
f. none of the above are correct
Which of the following activates carbohydrate and protein metabolism?
Potassium
Magnesium
Calcium
Sodium
Which of the following is almost all stored in bone?
Potasium
Which of the following, when administered in extremely high doses, can cause life-threatening hypotension?
Which acid-base imbalance has an excess of bicarbonate ions?
metabolic acidosis
metabolic alkalosis
Metabolic acidosis is treated with __________ drugs.
alkalinizing
acidifying
Alkylating drugs can work in any cell cycle-phase.
__________ alkylation drugs work by separating a base pair from its partner.
Bifuctional
Monofunctional
Anti-metabolite drugs resemble DNA base pairs.
Anti-metabolite drugs work in any cell cycle-phase.
An adverse effect of the anti-neoplastic drug Methotrexate is that it can suppress bone marrow.
Antibiotic anti-neoplastic drugs inhibit the cellular processes of both normal and malignant cells.
These drugs prevent androgens converting into estrogen in post-menopausal women.
aromatase inhibitors
anti-estrogens
anti-androgens
gonadotropin-releasing hormone analogues
androgens
These drugs prevent androgen binding.
These drugs increase luteinizing hormone that increases testosterone.
Anti-androgens
The natural anti-neoplastic Vinca alkaloids are cell cycle-specific for __________.
M phase (mitosis)
G2 and late S phases
Monoclonal antibodies cause tumor death by:
a. inducing programmed cell death
b. recruiting the immune system to attack tumor cells
c. delivering toxic chemotherapy drugs to the tumor site
d. all the above are correct
Topoisomerase I inhibitors:
a. mediate relaxation of supercoiled DNA
b. prevent DNA resealing
c. cause DNA strand breakage
d. impair DNA synthesis
Targeted anti-neoplastic therapies go after proteins associated with the growth of cancers and so can also cause fetal harm or death.