Intracellular [Ca2+]?

Extracellular [Ca]?

Reason for low [Ca]?

Reason for high extracellular [Ca]?

Bone morphology?

Describe the change in Ca balance throughout life.

Bone function?

Bone = ? % BW

Order of 3 bone cells from outside in.

Which bone cell is related to macrophages?

Osteogenic cells

Are osteogenic cells responsible for formation of osteoclasts?

What is an osteoid

What is the mineral component of bone matrix?

Role of hydroxyapatite?

Osteoid mineralisation is dependant on?

What happens in Vit D3 deficiency for children? for adults?

Osteomalacia

Where is Alkaline Phospatase expressed?

What are Alk Phos biomarkers of?

Action of Alk Phos?

Why does pyrophosphate hydrolysis lead to bone formation?

Osteoclast formation occurs by?

Characteristic of activated osteoclasts?

How do osteoclasts resorb bone?

How do Osteoclast precursors become activated to become mature osteoclasts?

Osteopetrosis

4 steps of bone remodelling cycle

How often are skeleton renewed?

Where are calcitonin produced?

Role of PTH (Ca absorption)

Role of PTH

Why does PTH induce loss of phosphate?

Why does PTH induce loss of bicarbonate?