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What are the different types of anxiety disorders?
What are the two excitatory amino acid neurotransmitters?
What are the two inhibitory amino acid neurotransmitters?
Which is the GABA receptor that is metabotropic?
Is it GABA-A or GABA-B which mediates fast inhibitory transmission?
Which ion is GABA-A selective for?
How many subunits are in each GABA-A ion channel receptor?
What is the orthosteric site (for GABA-A R)?
What are the agonists and antagonists at the orthosteric site on the GABA-A receptor?
What is the allosteric site?
What are examples of allosteric agonists and antagonists for GABA-A receptors?
What is an inverse agonist for a GABA-A receptor?
Do orthosteric and allosteric agonists increase or decrease inhibitory neurotransmission in the brain?
Which type of G protein is the GABA-B (metabotropic) receptor coupled with?
What is an example of an agonist and antagonist at GABA-B receptors?
How do post-synaptic GABA-B receptors produce inhibition?
How do pre-synaptic GABA-B receptors produce inhibition?
What are the physiological effects of benzodiazepines?
How do benzodiazepines affect GABA-A receptors?
Do benzodiazepines have a high or low lipid solubility?
What are the pharmacokinetics of the benzodiazepine Zoipidem?
What are the pharmacokinetics of the benzodiazepine diazepam?
What are the pharmacokinetics of the benzodiazepine Clonazepam?
What is status epilepticus and which benzodiazepine is used?
What are the adverse effects of benzodiazepine agonists?
What are some examples of barbiturates?
How do barbituates affect the nervous system?
What can be non-genetic causes of epilepsy?
What is the main mutation that causes inherited/familial epilepsy?
What are the characteristics of epilepsy?
What different problems result during a seizure due to the affected areas of the brain?
What can be triggers for epilepsy?
What method is used to diagnose epilepsy?
What is a generalised (grand mal) epileptic seizure?
What is a generalised (petit mal) seizure?
What is a partial seizure?
In what ways can GABA transmission be increased?
How to uptake inhibitors help increase GABA (inhibitory) transmission?
What is GABA synthesised from? And what enzyme is required?
How is GABA metabolised?
How do anti-epileptic drugs work on excitatory synapses?
What are the typical symptoms of depression?
Is there a genetic component to depression?
What is Iproniazid?
What does Reserpine do?
What are the three main classes of antidepressants?
Is it MAOI type A or B which are good antidepressants?
Why can MAOIs cause problems?
What is the synthesis pathway involving dopamine, NA and adrenaline?
What is the 'cheese effect' in relation to MAOIs?
What population of neurones is the main area of serotonin release?
What are the functions of serotonin?
How does BDNF relate to depression?
What approaches/treatments are taken for bipolar disorder/depression?
Electroconvulsive shock therapy (ECT)
What does dopamine do?
What are the dopaminergic pathways in the CNS? And what are they involved in?
What is the cellular pathway of D1 type (D1 and D5) dopamine neurones?
What is the cellular pathway of D2 type (D2, D3 and D4) dopamine neurones?
How do amphetamines and cocaine affect dopamine transmission?
How do amphetamines affect DA?
What are amphetamine-like drugs used to treat?
What is the prevalence of schizophrenia?
What are the negative symptoms of schizophrenia?
What are the positive symptoms of schizophrenia?
How is schizophrenia observed in animal models?
What are some of the structural differences between schizophrenic and normal brains?
What is a side effect of antipsychotic drugs?
What are the signalling pathways associated with the D2 receptor?
What is the schizophrenia Dopamine Hypothesis?
What is the relation between dopamine and Parkinson's disease?
