Schließen
The majority of drug targets (receptors) are proteins coded for in the genome
How to clone a receptor gene
Uses for gene code
Amino acid sequence of drugs
How is the muscarinic Ach receptor different from the nicotinic Ach receptor?
Components of a muscarinic Ach receptor (g-protein coupled receptor)
Components of a nicotinic Ach receptor (ion channel)
Function:
How muscarinic receptors work (G-proteins)
Function:
How nicotinic receptors work
Identification of protein families (similar proteins)
Classification of receptors
How knowing the structure of the ligand binding site may help rational drug design
EG the family of G-protein coupled receptors
Pharmacogeonomics
Example of pharmacogeonomics:
succinylcholine
Genetic adverse effects of drugs:
example of halothene
Solutions to adverse effects of halothene
personalised medicine
Gene therapy
