Most drugs mimic or block cell function through these three things

Chemotherapeutic agents act on what?

How does lipid solubility impact absorption of a drug?
What else impacts absorption?

Agonists ... the target when bound
Antagonists ... the target bound

What is the difference between a drug with high affinity and efficacy?

What does KD measure? On a graph, where is KD?

What does EC50 measure?

Reversible antagonist drugs can be overcome by what?
How do they impact the agonist-response curve?

Irreversible antagonists impact the graph by

Concentration of drug plotted against %of receptor occupied produces a graph with a ... shape
While log[D] produces a .... shape

What 3 factors increase drug potency?

Pharmacokinetics measures what ... does to ....
While Pharmacodynamics measures what ... does to ....

How can drugs interact with each other?

Where does metabolism of drugs occur? What are the two phases?

Where do drugs get excreted? What is t1/2?

Which type of drugs are excreted more slowly?

What are the 4 phases of clinical trials a drug must undergo?

What is a physiological antagonist?

What does the agonist response curve measure? What is on the X and Y and what shape?