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Midterm Practice

Frage 1 von 50

1

The rate of Ca+ diffusion across a membrane is dependent on -

Wähle eine der folgenden:

  • Permeability of the membrane on the solute

  • Concentration gradient

  • Existence of carriers and/or channels for the solute

  • All of these are true.

Erklärung

Frage 2 von 50

1

Na+ concentration on either side of a membrane plays a role in osmolarity, even if it is not permeable to the membrane.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 3 von 50

1

The rate of diffusion for a solute across a membrane is dependent on -

Wähle eine der folgenden:

  • Concentration gradient

  • Temperature

  • Viscosity of the fluid

  • All of these.

Erklärung

Frage 4 von 50

1

Homeostasis in physiological systems refers to the maintenance of a static or constant conditions in the internal environment.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 5 von 50

1

Influences on receptor-mediated channels refers to a protein

Wähle eine der folgenden:

  • Allowing other solutes to cross a membrane, after linking to a primary molecule.

  • Allowing other solutes to cross a membrane, after a voltage change to the inside of the cell.

  • Allowing other solutes to cross a membrane, after pressure changes to the inside of the cell.

  • All of these.

Erklärung

Frage 6 von 50

1

Osmotic pressure is the pressure necessary to allow the movement of water across a membrane.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 7 von 50

1

Secondary active co-transporter proteins in a cell membrane have which of the properties listed below?

Wähle eine der folgenden:

  • Selectiveity

  • Uses energy from solute concentration gradient (runs downhill)

  • Saturable

  • All of these.

Erklärung

Frage 8 von 50

1

Which statement below is NOT true?

Wähle eine der folgenden:

  • Voltage is "pressure" that moves electrons or ions through a circuit.

  • Current is the number of electron or ions moving per unit of time.

  • Resistance is not associated with the lipid membrane.

  • Conductance is the reciprocal of resistance.

Erklärung

Frage 9 von 50

1

Active transport differs from facilitated diffusion in that it uses energy to move a substance uphill against its concentration gradient.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 10 von 50

1

The equilibrium potential for a particular ion is the voltage in which that ions movement across a lipid membrane comes to a relative stop.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 11 von 50

1

Depolarizing the membrane of excitable cells by ~10mV will initiate -

Wähle eine der folgenden:

  • increases in Na+ conductance (ability to move across the membrane)

  • decreases Na+ in conductance (ability to move across the membrane)

  • closing of Na+ ions protein channels

  • cell death

Erklärung

Frage 12 von 50

1

The Nernst Equation is important for:

Wähle eine der folgenden:

  • Determining the absolute membrane potential

  • Determining the electrical potential difference, for a single ion, needed to counter the concentration difference.

  • Determining the concentration difference, for multiple ion, needed to counter the concentration difference.

  • None of these

Erklärung

Frage 13 von 50

1

When determining the "equilibrium potential" for Na+, we have to assume the membrane is permeable to Na+.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 14 von 50

1

Which channel is most responsible for the depolarization phase of an action potential across a cell membrane?

Wähle eine der folgenden:

  • Open Na+ channels

  • Open K+ channels

  • Open Ca++ chanels

  • All of these

Erklärung

Frage 15 von 50

1

Which process listed below is most responsible for maintaining the electrochemical gradient?

Wähle eine der folgenden:

  • Facilitated diffusion of Na+

  • Na+/K+ pump

  • Ca++ storage

  • Starbuck's Coffee and Krispy Cream.

Erklärung

Frage 16 von 50

1

What two factors make using the Goldman Equation more appropriate for determining the "Resting Membrane Potential", instead of using the Nertz Equation?

Wähle eine der folgenden:

  • The number of voltage-gated channels located in the membrane and concentration of ions inside the cell.

  • The relative ion concentration on either side of the membrane and the relative permeability of the membrane to the ions.

  • The amount of Krispy Cream donuts and Starbuck's coffee outside the cell.

  • The inclusion of the relative permeability of the ions.

Erklärung

Frage 17 von 50

1

Which ion is most responsible for the initial change (depolarization) in membrane potential during the action potential?

Wähle eine der folgenden:

  • Na+

  • K+

  • Ca++

  • Cl-

Erklärung

Frage 18 von 50

1

Ligand-gated channels are important for initiating an action potential at the neuromuscular junction.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 19 von 50

1

Slow, oxidative muscle fibers -

Wähle eine der folgenden:

  • Use mainting oxidative phosphorylation to generate ATP.

  • Have large amounts of mitochondria.

  • Have large blood supply.

  • All of these.

Erklärung

Frage 20 von 50

1

The sarcoplasmic reticulum stores __________ when a muscle is relaxed and releases it for binding to _______ during contraction.

Wähle eine der folgenden:

  • calcium; troponin

  • calcium; tropomyosin

  • sodium; tropomyosin

  • potassium; tropinin

Erklärung

Frage 21 von 50

1

Put in to the correct sequence the following events involved in muscle cell contraction.

1. Voltage-gated sodium channels open, allowing sodium to flow in.
2. Spreading action potential reaches T-Tubles activating a DHP molecule.
3. Acetylcholine binds to receptors on muscle cell membrane.
4. Ligand-gated receptors allow small amounts of sodium into the cell changing membrane potential 10mV(+).
5. If enough sodium moves into the muscle cell, an impulse (action potential) develops.

Wähle eine der folgenden:

  • 3,4,1,5,2

  • 2,1,3,4,5

  • 2,4,3,1,5

  • 3,4,5,1,2

Erklärung

Frage 22 von 50

1

Which molecule listed below is responsible for "physically" inhibiting the binding of the myosin head to the active binding site on actin?

Wähle eine der folgenden:

  • Troponin

  • Tropomyosin

  • G-actin

  • all of these

Erklärung

Frage 23 von 50

1

In order to allow discrete events to occur, calcium is rapidly removed from the cytoplasm by __________.

Wähle eine der folgenden:

  • dihydropyridime channels

  • calcium-sequestering proteins in the cytoplasm

  • calcium pumps in the sarcoplasmic reticulum

  • DHP receptor

Erklärung

Frage 24 von 50

1

When an action potential is generated within a motor unit -

Wähle eine der folgenden:

  • the muscle cells of the motor unit will occasionally contract.

  • only select muscle cells within the motor unit are stimulated to contract.

  • every muscle cell of the motor unit is stimulated to contract.

  • the muscle cells from the neighboring motor unit will contract.

Erklärung

Frage 25 von 50

1

The releasing of Ca++ inside the skeletal muscle cell (intracellular) is initiated by which protein receptor listed below?

Wähle eine der folgenden:

  • Actin

  • DHP

  • Myosin

  • Tropomyosin

Erklärung

Frage 26 von 50

1

The t-tubules are an extension of the cell membrane of the skeletal muscle cell.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 27 von 50

1

The t-tubule of cardiac muscle

Wähle eine der folgenden:

  • form the Z lines

  • stores K+

  • provides a means of rapidly transmitting action potential to the sarcoplasmic reticulum via the DHP molecule

  • are larger than those found in skeletal muscle.

Erklärung

Frage 28 von 50

1

The fusing of synaptic vesicles with the terminal button membrane is initiated by Ca++ influx into the cell.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 29 von 50

1

The plateau of the cardiac action potential results from opening of voltage-gated, slow _______ channels in the membrane of the cardiac cell.

Wähle eine der folgenden:

  • sodium

  • potasium

  • calcium

  • chloride

Erklärung

Frage 30 von 50

1

Heart muscle has long refractory period due to extended K+ channel opening.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 31 von 50

1

Increased activity within the parasympathetic nervous system will result in changes primarily within the

Wähle eine der folgenden:

  • sinoatrial node only

  • atrioventricular node only

  • ventricles only

  • sinoatrial node and atrioventricular node

  • sinoatrial node, atrioventricular node, and ventricles

Erklärung

Frage 32 von 50

1

Which of the following is NOT involved in triggering the normal coordinated contraction of cardiac muscle cells?

Wähle eine der folgenden:

  • release of a neurotransmitter.

  • change in membrane potential within individual cardiac muscle cells

  • initiation of an action potential

  • a pacemaker potential

  • the conduction system of the heart.

Erklärung

Frage 33 von 50

1

The long refractory period of cardiac muscle prevents tetanic contraction of the heart.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 34 von 50

1

The sinoatrial node requires external stimulation in order to generate an action potential.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 35 von 50

1

Which of the following EKG events represents the depolarization of the ventricle?

Wähle eine der folgenden:

  • P wave

  • QRS complex

  • PR interval

  • T wave

Erklärung

Frage 36 von 50

1

The spontaneous action potential generated by the Sino-Atrial Node, Atrio-ventricular Node, and Purkinje Fibers is due to K+ leaking across the cardiac muscle cell membrane.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 37 von 50

1

The depolarization of the atria (by the Sino-Atrial Node) will be communicated (sent) to the ventricles (Purkinje fibers) by the _________.

Wähle eine der folgenden:

  • Sarcoplasmic reticulum

  • DHP molecule

  • A-V bundle (bundle of His)

  • Actin and myosin filaments.

Erklärung

Frage 38 von 50

1

Diastolic pressure generated by the right ventricle must overcome pressure in the aorta to get blood flow out to the rest of the body.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 39 von 50

1

The Frank-Starling mechanism of heart contraction state that as more blood enters the heart, the heart will respond by contracting with greater force. Which is the statements below helps explain how this works?

Wähle eine der folgenden:

  • The pacemaker mechanism of the heart is stimulated by increased input of blood to the left ventricle.

  • Parasympathetic inhibition of contraction will allow more force to be generated.

  • Stretched cardiac muscle has better actin/myosin filament alignment.

  • All of these.

Erklärung

Frage 40 von 50

1

Contraction of motor units is a(n) ____________ manner allows a muscle to maintain a level of force for a duration of time without fatiguing.

Wähle eine der folgenden:

  • Synchronous

  • Asymmetrical

  • Asynchronous

  • Random

Erklärung

Frage 41 von 50

1

Skeletal muscle fibers operate at near-optimal sarcomere length in the normal individual.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 42 von 50

1

The speed at which the action potential travels through different parts of the heart conduction system is dependent on -

Wähle eine der folgenden:

  • blood flow through the heart

  • functioning of the Atrio-ventricular valve.

  • resistance to the spread of the action potential

  • phases of the moon.

Erklärung

Frage 43 von 50

1

The influx of calcium into the axon terminal of a chemical synapse is responsible for the ____________.

Wähle eine der folgenden:

  • initiation of the action potential

  • termination of an action potential

  • fusion of the vesicles to the membrane and their exocytosis

  • movement of calcium through gap junctions

Erklärung

Frage 44 von 50

1

Which substance below could be used to treat 'flaccid paralysis'?

Wähle eine der folgenden:

  • Curare

  • Botulinum Toxin

  • Tetanus Toxin

  • Diisoprophyl fluorophosphate

Erklärung

Frage 45 von 50

1

Pressure in the right atria of the heart is ~0

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 46 von 50

1

Ventricular cardiac muscle cells demonstrate a stable resting membrane potential with no evidence of the slow depolarization of the specialized cardiac pacemaker cells.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 47 von 50

1

Which specialized muscle tissues of the heart can generate the greatest number of action potentials in a minute?

Wähle eine der folgenden:

  • Sino-Atrial Node

  • Atrio-Ventricular Node

  • Purkinje fibers

  • All of the these.

Erklärung

Frage 48 von 50

1

An ion's overall electrochemical gradient will tend to force that ion across the membrane in a direction that will cause membrane potential to move toward that ion's equilibrium potential.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 49 von 50

1

The electrical potential of a membrane at rest is closest to potassium's equilibrium potential because ___________.

Wähle eine der folgenden:

  • more sodium channels are open, allowing more sodium to move into the cell.

  • more potassium channels are open, allowing more potassium to move in or out of the cell.

  • more sodium channels are closed, allowing less sodium to move in or out of the cell.

  • all of the above.

Erklärung

Frage 50 von 50

1

As a consequence of Frank-Starling's Law of the heart, _________________________.

Wähle eine der folgenden:

  • an increase in end-systolic volume will increase stroke volume.

  • a decrease in end-diastolic volume will increase stroke volume.

  • an increase in end-diastolic volume will increase stroke volume.

  • stroke volume is unaffected by end-diastolic volume.

Erklärung