Liz Maas
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Liz Maas
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Development of the CNS and Related Birth Defects (CF9)

Frage 1 von 12

1

The three vesicle stage occurs at the 3rd week of gestation. The five vesicle stage occurs at the 5th week of gestation

Wähle eine der folgenden:

  • both true

  • first true second false

  • first false second true

  • both false

Erklärung

Frage 2 von 12

1

The Prechodal plate produces FGF to regulate midline structure development of the brain and face. The Anterior Neural Ridge produces SHH to regulate development of the telencephalon.

Wähle eine der folgenden:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both statements false

Erklärung

Frage 3 von 12

1

The prechodal plate is derived from?

Wähle eine der folgenden:

  • Ectoderm

  • Mesoderm

  • Endoderm

  • Dermis

Erklärung

Frage 4 von 12

1

The isthmus is between the forebrain and midbrain and regulates their development. It produces both FGF and WNT.

Wähle eine der folgenden:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false

Erklärung

Frage 5 von 12

1

Some neurons from the corpus striatum gives rise to part of the cerebral cortex. Most of the cerebral cortex comes from the pallium.

Wähle eine der folgenden:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false

Erklärung

Frage 6 von 12

1

Which of the following is a vertebral fusion defect where both the neural tissue and meninges protrude?

Wähle eine der folgenden:

  • spina bifida occulta

  • meningocele

  • meningomyelocele

  • myeloschisis

  • Arnold-Chiari malformation

Erklärung

Frage 7 von 12

1

Which of the following is incorrectly matched?

Wähle eine der folgenden:

  • Spina Bifida occulta: the bony defect is covered by skin, intact spinal cord

  • Spina Bifida Cystica: there is a protrusion of meninges and neural tissue (meningomyelocele)

  • Meningocele: only the meninges protrude

  • Anencephaly- open brain

  • Craniorachischisis: neural tube defect at the brain and spinal cord

Erklärung

Frage 8 von 12

1

In normal development, the spinal cord elongates faster than the vertebral column. In Spina Bifida Cystica, as the vertebral column elongates, the force stretches the spinal cord which causes the herniation of the cerebellum.

Wähle eine der folgenden:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false

Erklärung

Frage 9 von 12

1

The bone most frequently affected by neural tube defects is the occipital bone. Small defects can cause meningoencephalocele.

Wähle eine der folgenden:

  • Both true

  • First true, second false

  • First false, second true

  • Both false

Erklärung

Frage 10 von 12

1

Meningoencephalocele is protrusion of just the brain tissue and meninges. Meningohydroencephalocele involves protrusion of the meninges, brain tissue and ventricle.

Wähle eine der folgenden:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both statements false

Erklärung

Frage 11 von 12

1

Which of the following is correct?

Wähle eine der folgenden:

  • Lobar HPE- one telencephalic vesicle, one eye, one nasal chamber, other midline defects

  • Alobar HPE- one telencephalic vesicle, one eye, one nasal chamber, other midline defects

  • Smith-Lemli-Opitz involves EMX 2, is autosomal recessive, assorted defects of face, heart, brain, limbs

  • Schizencephaly- involves DHCR 7, causes large clefts in cerebral hemispheres

  • Microcephaly- caused by smaller cranial vault leading to less brain development

Erklärung

Frage 12 von 12

1

Hydrocephaly is often due to a blockage in the lateral and third ventricles. The accumulated fluid leads to thinner bones of skull and cerebral cortex and an enlarged head.

Wähle eine der folgenden:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false.

Erklärung

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