Biological screening

Biological assays

Methods of developing new drugs

Reasons for modification of chemical structure of existing drugs

Types of screening

Simple screening

Blind screening

Blind screening tests

Primary screening vs. secondary screening

Neuropharmacological tests

Neuropharmacological tests : Behavioural responses

Behavioural responses: Awareness

Awareness : Consciousness

Awareness : Visual placing (Righting reflex)

Awareness : Stereotypy

Awareness : Passivity

Behavioural responses : Mood

Mood : Grooming

Mood : Vocalization

Mood : Restlessness

Behavioural responses : Motor activity

Motor activity : Spontaneous activity

Motor activity: Reactivity

Motor activity : Touch responses

Motor activity : Pain response

Neuropharmacological tests : Neurological responses

Neuropharmacological tests : Autonomic responses

Autonomic responses : Optical signs

Autonomic responses : Secretory signs

Autonomic responses : General signs