In these situations, antibiotic therapy should be started on admission to hospital for labour or rupture of membranes, ideally at least 4 hours before delivery, and continued until the neonate is delivered.

Recommended intra-partum antibiotic therapy:

· IV benzylpenicillin 3 g dose followed by 1.8g 4 hourly until delivery

OR If penicillin hypersensitivity (excluding immediate hypersensitivity), IV cephazolin 2 g dose 8 hourly until delivery
OR If immediate penicillin hypersensitivity and GBS isolate known to be susceptible to clindamycin, IV clindamycin 600 mg 8-hourly until delivery
OR If immediate penicillin hypersensitivity and GBS isolate resistant to clindamycin or results of susceptibility testing are not available, IV vancomycin

	Erstellt von Abhijit Das vor mehr als 10 Jahre

Fellowship Obstetrics Notiz am Antibiotics in obstetrics, erstellt von Abhijit Das am 12/07/2016.