Sequence of bilirubin metabolism

Majority of RBCs degraded in?

Immature or defective RBC precursors degraded where?

Cytochromes degraded where?

Heme oxygenase

Biliverdin reductase

Why is UCB so stable?

UCB is transported to the liver via?

OATP

GST

UGT

CB

MRP2

Urobilinogen

Stercobilin

Excretion in stool

Reabsorption into enterohepatic circulation

Urinary excretion

Diazo reaction

TBIL

DBIL

IBIL

Hyperbilirubinemia values

Physiologic jaundice

Phototherapy

Kernicterus

Prehepatic jaundice

Hepatic Jaundice

Posthepatic jaundice

Prehepatic jaundice lab values

Hepatic jaundice

Posthepatic labs