E2. _Bioc_Lec1_ CarbMetaAndGlyc

Frage 1 von 50

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Hexose are ( 6, 5, 4, 7 ) Carbon ( Carbohydrates, Proteins, Nucleic Acids, Lipids ) and are typically used for energy metabolism. Examples include ( Glucose, Fructose, Mannose, and Galactos, RIbose, Deoxyribose, NADH, and Galactos )e.

Pentose are ( 5, 4, 6, 7 ) carbon carbohydrates and are typically used in ( larger molecules, energy metabolism, plants, not humans ). Examples include ( Ribose, Deoxyribose, and NADH, Glucose, Fructose, Mannose,and Galactose ).

The difference in deoxyribose and ribose is with the ( H/OH, OH/H, N/lackthereof, Lackthereof/N, COO/CO, CO/COO ) group at the ( 2', 1', 3', 4', 5', 6' ) location. ( DNA, RNA ) is more stable than ( RNA, DNA ).

Stereoisomers- ( Alpha, Beta, Gamma, Delta ) is when the ( 1', 2', 3', 4' ) OH group is ( below, above, on the same plane as ) the ring, while ( beta, alpha, gamma, delta ) is when the ( 1, 2, 3, 4 )' OH group is ( above, below, in the same plane as ) the ring. This difference has a ( profound, minimal, undocumented/unexplored ) impact on its biological uses and enzyme binding.

( D and L, A and B, X and Y, G and M, Q and R, R and L, C and D ) sugars are enantiomers, which means they are ( mirror, identical, completely different, 90 degrees rotated ) images of each other. Most mammal sugars are in the ( D, L ) configuration, while ( L, D ) sugars are typically found in plants and microorganisms.

Erklärung

Frage 2 von 50

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Polysaccharides can be used for _____________ in plants and animals

Wähle eine der folgenden:

storage
structure
all of the above
none of the above

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Frage 3 von 50

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Disaccharides are used for

Wähle eine der folgenden:

Storage
Structure
All of the above
None of the above

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Frage 4 von 50

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Beta Glucose linkage is typically seen in

Wähle eine der folgenden:

Glycogen
Starch
Chitin
Cellulose

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Frage 5 von 50

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Chitin uses ____ as its main building block

Wähle eine der folgenden:

Alpha linked glucose
Beta linked glucose
gamma linked glucose
N acetyl glucosamine (a linked)
N acetyl Glucosamine (beta linked)
N acetyl Glucosamine (gamma linked)

Erklärung

Frage 6 von 50

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Glycogen uses glucose in what kind of linkage?

Wähle eine der folgenden:

Alpha
Beta
Gamma
Delta
Reserve
CIS
Trans
Mirrored
Trick question, they arent linked

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Frage 7 von 50

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Disaccharides can enter the metabolic pathways with no prior modification or cleveage

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 8 von 50

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Glycolysis is the breakdown of glucose into Acetyl-CoA

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 9 von 50

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Fülle die Lücken, um den Text zu vervollständigen.

is converted into compounds, coupled with production.

Glycolysis occurs in cells of the body and the reaction occurs exclusively in the .

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Frage 10 von 50

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Glycolysis requires Oxygen to procede

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 11 von 50

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Fülle die Lücken, um den Text zu vervollständigen.

is a sequence of reactions that convert to . This requires an investment of but produces a net of . There is one step that converts NAD to NAD.

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Frage 12 von 50

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Glycolysis is a unique reaction chain that is not linked to other biochemical pathways

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 13 von 50

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glucose (6-C; Six Carbon) is broken into:

Wähle eine der folgenden:

2 3-C molecules
3 2-Cmolecules
1 4-C molecule and 1 2-Cmolecule
none of the above
1 5-C molecule and 1 CO2 (1-C) molecule

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Frage 14 von 50

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ALL of the enzymes used in the glycolysis pathway are unique to the forward reaction of glycolysis to pyruvate

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 15 von 50

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Phosofructokinase is NOT a rate limiting setp

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 16 von 50

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The Hexokinase reaction precedes the Glucokinase reaction

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 17 von 50

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GLUCOKINASE is ONLY found in the LIVER and PANCREAS
HEXOKINASE is found in ALL OTHER CELLS/TISSUES.

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 18 von 50

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Outside of location, the major difference between Hexokinase and Glucokinase is the fact Glucokinase has a lower affinity for Glucose.

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 19 von 50

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Hexokinase catalyzes the reaction of Glucose to Glucose 1 Phosphate

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 20 von 50

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Glucose gets converted to fructose as a part of glycolysis.

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 21 von 50

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Phospofructokinase catalyzes the reaction of Fructose 6 phosphate to Fructose 1,6 bisphosphate

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 22 von 50

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Fülle die Lücken, um den Text zu vervollständigen.

Aldose catalyzes the reaction of into

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Frage 23 von 50

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Aldose cleave Glucose 1,6 bisphosphate into dihydroxyacetone phosphate and glyceraldehyde 3 phosphate

Wähle eins der folgenden:

WAHR
FALSCH

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Frage 24 von 50

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Dihydroxyacetone phosphate gets directly converted to 1,3 bisphosphoglycerate

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 25 von 50

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NADH is produced by which enzyme, which also requires Mg as a cofactor

Wähle eine der folgenden:

Hexokinase
Phospohexokinase Isomerase
Aldoase
glyceraldehyde 3 phosphate dehydrogenase

Erklärung

Frage 26 von 50

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Which of the following enzymes (or their associated rxns) require Mg?

Wähle eine oder mehr der folgenden:

Hexokinase
Phosphoglucose isomerase
phosphofructosekinase
aldoase
Triosephosphate isomerase
glyceraldehyde 3 phosphate dehydrogenase
phosphoglycerate kinase
phosphoglycerate mutase
Enolase
Pyruvate Kinase

Erklärung

Frage 27 von 50

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In Anaerobic conditions NADH is used with pyruvate to generate lactate

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 28 von 50

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It is better to rest completely when fatigued (high lactate levels) from exercise

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 29 von 50

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Fülle die Lücke, um den Text zu vervollständigen

1,3 bisphosphoglycerate to 3 phosphoglycerate produces ATP via

Erklärung

Frage 30 von 50

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The major regulatory points are which of the following enzymes

Wähle eine oder mehr der folgenden:

phosphofructosekinase
hexokinase (glucokinase)
pyruvate kinase
phosphoglucose isomerase
aldolase
Triosephosphate isomerase

Erklärung

Frage 31 von 50

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The major regulatory points are all reversible reactions using the same enzyme.

Wähle eins der folgenden:

WAHR
FALSCH

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Frage 32 von 50

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Pyruvate kinase catalyze the forward and reverse reaction from phosphoenolpyruvate to pyruvate, and also generates one atp molecule

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 33 von 50

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Which enzyme is the RATE LIMITING STEP

Wähle eine der folgenden:

Phosphofructokinase
Hexokinase/Glucokinase
Pyruvate Kinase

Erklärung

Frage 34 von 50

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Phosphofructokinase responds to

Wähle eine oder mehr der folgenden:

energy state (ATP as a positive regulator)
H+ concentration (lactate is a positive regulator)
Citrate s a positive regulator
Citrate as a negative regulator
energy state (ATP as a negative regulator)
H+ concentration (lactate is a negative regulator)
Insulin to glucagon ratio in blood (Fructose 2 6bisphosphate is a positive regulator)
Insulin to glucagon ratio in blood (Fructose 2 6bisphosphate is a negative regulator)

Erklärung

Frage 35 von 50

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What is the effect of F-2,6-BP on phosphofructokinase activity on the graph [Velocity (Y) vs concentration of F6P (x)]

Wähle eine der folgenden:

Shifts Graph Left, It is an activator
Shifts Graph Right, It is an activator
Shifts Graph Left, It is an inhibitor
Shifts Graph Right, It is an inhibitor

Erklärung

Frage 36 von 50

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Fructose 2, 6 Bis Phosphate is produced by Glycolysis

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 37 von 50

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Pyruvate Kinase is phosphorylated to make it more active

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 38 von 50

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Phosphorlyation of PK is downregulated by low blood glucose levels.

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 39 von 50

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Fülle die Lücken, um den Text zu vervollständigen.

Pyruvate is upregulated by and downregulated by and

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Frage 40 von 50

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Summary Slide!

is the conversion of to with and NAD production.

Glycolysis is critical for brain and erythrocyte and muscles.

, , and catalyze key steps in glycolysis.

catalyzed the and is by levels of .

is a site of secondary . it undergoes to make it .

Under conditions NAD is regenerated by conversion of to .

Erklärung

Frage 41 von 50

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Fülle die Lücken, um den Text zu vervollständigen.

According to the video from slide 16, Glycolysis can be thought of in 3 different phases.

1) Energy (steps to )
2). Glucose (steps to )
3). Energy (steps to )

Erklärung

Frage 42 von 50

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Fülle die Lücken, um den Text zu vervollständigen.

sensing is conducted by the . They require glucose via the transport protein, and its via the pathway.

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Frage 43 von 50

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The pancreas uses hexokinase not glucokinase

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 44 von 50

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To sense the levels of glucose in the blood, Pancreatic Beta cells uptake glucose via GLUT2, where it is then processed into ATP (VIa glycolysis, the TCA and Phos Ox). The ATP levels rise and open and K channel which allows an influx of K, triggering membrane depolarization. This then triggers a Voltage dependent Calcium channel to close allowing an influx of Ca into the cell which triggers the release (exocytosis) of insulin filled vesicles.

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 45 von 50

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A defect in the gene coding for which enzyme of glycolysis has been linked to early onset diabetes (T-2)

Wähle eine der folgenden:

Hexokinase (II)
Glucokinase
Phospofructokinase
Aldolase
Pyruvate Kinase
Phosphoglycerate kinase

Erklärung

Frage 46 von 50

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Just seeing food can trigger the release of insulin via the parasympathetic nervous system

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 47 von 50

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Which cycle converts converts lactate back into glucose via glucoenogensis?

Wähle eine der folgenden:

Cori Cycle
Krebs Cycle
Alanine Cycle
Kori Cycle
Phenlyalanine Cycle
Calvin Cycle

Erklärung

Frage 48 von 50

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The alanine cycle recyles alanine produced by glucose metabolism to pyruvate and alanine. This cycle occurs exclusively in muscle cells and converts alanine back into glucose via pyruvate and gluconeogensis.

Wähle eins der folgenden:

WAHR
FALSCH

Erklärung

Frage 49 von 50

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DISEASE QUESTION PLACEHOLDER

Wähle eine der folgenden:

This one
not this one

Erklärung

Frage 50 von 50

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Label the substrates/products, enzymes, and net reaction. Use Tags labeled with the prefix "R: " for the net reaction box in the bottom right. If the molecule is used multiple times, is the lowest suffix (ie_1) first.

{"1.95877_9.47368":[{"id":11204392,"answer":"Pyruvate","x":1.95877,"y":9.47368}],"11.6775_12.8521":[{"id":11204391,"answer":"Pyruvate Kinase","x":11.6775,"y":12.8521}],"7.47783_28.2456":[{"id":11204393,"answer":"Phosphoenolpyruvate","x":7.47783,"y":28.2456}],"22.8523_21.0526":[{"id":11204394,"answer":"Enolase","x":22.8523,"y":21.0526}],"32.5764_16.1404":[{"id":11204405,"answer":"Glucose","x":32.5764,"y":16.1404}],"20.7498_32.6316":[{"id":11204395,"answer":"2phosphoglycerate","x":20.7498,"y":32.6316}],"43.2203_9.12281":[{"id":11204406,"answer":"Hexokinase/Glucokinase","x":43.2203,"y":9.12281}],"37.307_25.0877":[{"id":11204396,"answer":"Twice","x":37.307,"y":25.0877}],"38.8839_33.1579":[{"id":11204397,"answer":"Phosphoglycerate mutase","x":38.8839,"y":33.1579}],"51.7617_17.7193":[{"id":11204407,"answer":"Glucose 6 phosphate","x":51.7617,"y":17.7193}],"39.4095_44.5614":[{"id":11204398,"answer":"3 phosphoglycerate","x":39.4095,"y":44.5614}],"61.8799_12.1053":[{"id":11204408,"answer":"phosphoglucose isomerase","x":61.8799,"y":12.1053}],"61.0915_23.8596":[{"id":11204409,"answer":"Fructose 6 phosphate","x":61.0915,"y":23.8596}],"55.5724_42.9825":[{"id":11204399,"answer":"Phosphoglycerate Kinase","x":55.5724,"y":42.9825}],"52.4187_58.0702":[{"id":11204400,"answer":"1,3 Bisphosphoglycerate","x":52.4187,"y":58.0702}],"73.8379_35.7895":[{"id":11204413,"answer":"fructose 1,6 Bisphosphate","x":73.8379,"y":35.7895}],"67.1362_47.7193":[{"id":11204401,"answer":"Glyceraldehyde 3 phosphate dehydrogenase","x":67.1362,"y":47.7193}],"81.328_23.1579":[{"id":11204411,"answer":"Phosphofructose kinase","x":81.328,"y":23.1579}],"42.5632_73.1579":[{"id":11204417,"answer":"R: Glucose","x":42.5632,"y":73.1579}],"74.4949_44.2105":[{"id":11204402,"answer":"Glyceraldehyde 3 phosphate","x":74.4949,"y":44.2105}],"41.3806_83.8596":[{"id":11204420,"answer":"R: ATP_1","x":41.3806,"y":83.8596}],"60.9601_72.6316":[{"id":11204418,"answer":"R: Pyruvate","x":60.9601,"y":72.6316}],"83.5619_51.0526":[{"id":11204404,"answer":"triosephosphate isomerase","x":83.5619,"y":51.0526}],"92.1033_42.807":[{"id":11204415,"answer":"Aldolase (FructoseBisphosphateAldolase)","x":92.1033,"y":42.807}],"58.7262_84.7368":[{"id":11204419,"answer":"R: ATP_2","x":58.7262,"y":84.7368}],"42.4318_96.1404":[{"id":11204422,"answer":"NAD+","x":42.4318,"y":96.1404}],"86.4529_60.1754":[{"id":11204403,"answer":"Dihydroxyacetone phosphate","x":86.4529,"y":60.1754}],"49.5278_95.4386":[{"id":11204423,"answer":"E-","x":49.5278,"y":95.4386}],"73.3123_95.2632":[{"id":11204424,"answer":"NADH","x":73.3123,"y":95.2632}],"86.4529_84.7368":[{"id":11204421,"answer":"R: ATP_3","x":86.4529,"y":84.7368}]}

Ziehe eine Antwort zum richtigen orangen Punkt.

Pyruvate Kinase

Pyruvate

Phosphoenolpyruvate

Enolase

2phosphoglycerate

Twice

Phosphoglycerate mutase

3 phosphoglycerate

Phosphoglycerate Kinase

1,3 Bisphosphoglycerate

Glyceraldehyde 3 phosphate dehydrogenase

Glyceraldehyde 3 phosphate

Dihydroxyacetone phosphate

triosephosphate isomerase

Glucose

Hexokinase/Glucokinase

Glucose 6 phosphate

phosphoglucose isomerase

Fructose 6 phosphate

Phosphofructose kinase

fructose 1,6 Bisphosphate

Aldolase (FructoseBisphosphateAldolase)

R: Glucose

R: Pyruvate

R: ATP_2

R: ATP_1

R: ATP_3

NAD+

E-

NADH

	Erstellt von Sahil Bharwani vor etwa 10 Jahre

Biochem E2L1, GLYCOLYSIS. 49 is a palceholder till slides are released/

E2. _Bioc_Lec1_ CarbMetaAndGlyc

Frage 1 von 50

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

Erklärung

Frage 2 von 50

Polysaccharides can be used for _____________ in plants and animals

Wähle eine der folgenden:

Erklärung

Frage 3 von 50

Disaccharides are used for

Wähle eine der folgenden:

Erklärung

Frage 4 von 50

Beta Glucose linkage is typically seen in

Wähle eine der folgenden:

Erklärung

Frage 5 von 50

Chitin uses ____ as its main building block

Wähle eine der folgenden:

Erklärung

Frage 6 von 50

Glycogen uses glucose in what kind of linkage?

Wähle eine der folgenden:

Erklärung

Frage 7 von 50

Disaccharides can enter the metabolic pathways with no prior modification or cleveage

Wähle eins der folgenden:

Erklärung

Frage 8 von 50

Glycolysis is the breakdown of glucose into Acetyl-CoA

Wähle eins der folgenden:

Erklärung

Frage 9 von 50

Fülle die Lücken, um den Text zu vervollständigen.

is converted into compounds, coupled with production. Glycolysis occurs in cells of the body and the reaction occurs exclusively in the .

Erklärung

Frage 10 von 50

Glycolysis requires Oxygen to procede

Wähle eins der folgenden:

Erklärung

Frage 11 von 50

Fülle die Lücken, um den Text zu vervollständigen.

is a sequence of reactions that convert to . This requires an investment of but produces a net of . There is one step that converts NAD to NAD.

Erklärung

Frage 12 von 50

Glycolysis is a unique reaction chain that is not linked to other biochemical pathways

Wähle eins der folgenden:

Erklärung

Frage 13 von 50

glucose (6-C; Six Carbon) is broken into:

Wähle eine der folgenden:

Erklärung

Frage 14 von 50

ALL of the enzymes used in the glycolysis pathway are unique to the forward reaction of glycolysis to pyruvate

Wähle eins der folgenden:

Erklärung

Frage 15 von 50

Phosofructokinase is NOT a rate limiting setp

Wähle eins der folgenden:

Erklärung

Frage 16 von 50

The Hexokinase reaction precedes the Glucokinase reaction

Wähle eins der folgenden:

Erklärung

Frage 17 von 50

GLUCOKINASE is ONLY found in the LIVER and PANCREAS HEXOKINASE is found in ALL OTHER CELLS/TISSUES.

Wähle eins der folgenden:

Erklärung

Frage 18 von 50

Outside of location, the major difference between Hexokinase and Glucokinase is the fact Glucokinase has a lower affinity for Glucose.

Wähle eins der folgenden:

Erklärung

Frage 19 von 50

Hexokinase catalyzes the reaction of Glucose to Glucose 1 Phosphate

Wähle eins der folgenden:

Erklärung

Frage 20 von 50

Glucose gets converted to fructose as a part of glycolysis.

Wähle eins der folgenden:

is converted into compounds, coupled with production.

Glycolysis occurs in cells of the body and the reaction occurs exclusively in the .

GLUCOKINASE is ONLY found in the LIVER and PANCREAS
HEXOKINASE is found in ALL OTHER CELLS/TISSUES.