Hormones involved with body mass

Hormones involved with Linear growth

Where is GH secreted from?

What are the forms of GH?

Hormones homologous to GH?

Where is GHRH released from?

General GH Pathway

When is GH secretion increased?

When is GH secretion downregulated?

Maturation of GH protein

GH Secretion pattern?

GH signals by which pathway?

Effects of GH on target tissue

Effect of GH on the bones

Ghrelin and GH

Somatostatin

IGF interplay with GH

Indirect effects of IGF-1

IGF-1 is similar to what hormone in terms of receptor structure/activation?

IGF release in Aging

IGF-2

When is IGF-2 more predominant?

Describe Insulin, IGF-1, and IGF-2 receptors

Insulin Signaling Path

IGF-1 Signaling pathway

IGF-2 signaling

De-regulation or imbalance of IGF binding proteins leads to what?

Macrosomy

Leprochaunism

Factors that decrease growth

Factors increasing GH

Decreases in HGH

Dwarfism

Gigantism

Acromegaly

How does replacement therapy with GH affect the body?

Signs of GH deficiency?

Clinical manifestations of GH Deficiency