What is missing in a virus like particle?
Viral envelope
Viral capsule
Viral genome
VLPs are used because they produce Igs, but have no risk of infection
Which of the following protects against more forms of HPV?
Cervarix
Gardasil
cLIAs are Fluorescent Immunoassays that cause reduced fluorescence if the Ig present
What is produced by B cells on exposure to HPV?
Anti-L1
Anti-L3
Anti-L5
Which vaccine is most effective in men?
Cervarex
The efficiency of Gardasil is
98-100%
50-58%
70-78%
Cervarex lasts how long?
At least 3 years
At least 12 years
At least 7 years
Which of the following types of HPV virus can have a high or low risk of cancer?
Cutaneous
Mucosal
Which classifcation of E6/E7 levels has the highest risk of carcinogenic genetic changes?
1
3
What is altered in the epression of E7 at level 3?
Also has telomerase activity
Associates differently with Rb genes
Degredates p53 more efficiently
Anal cancer is more common in men than women
Anal cancer is associated with HPV in what % of cases?
97%
45%
83%
In all types of HPV, being immunocompromised increases the risk of developing cancer
What proportion o cervical cancers is HPV assoicated with?
99.2%
99.5%
99.7%
