What makes up the 5' cap on mRNA?
CH3-G-PPP-
CH3-A-P
CH3-T-PP
What is the role of the Cap and the PolyA tale?
Attract an RNA subunit of the ribosomes to initiate translation
Attract miRNAs that cut up unwanted mRNA
Attract RNAses that cut up unwanted mRNA
IRES stands for Internal Ribosome Entry Site
In IRES Translation, how do the highly organised secondary structures form?
From the long UTRs with multiple AUG regions
From the long UTRs with multiple AGA regions
From the long UTRs with multiple UGC regions
What is the role of proteases in IRES dependent translation?
Cleave the CAP to prevent the other pathway
Cleave miRNAs that will break down viral RNA
The ribosome in IRES is attracted by the breakdown of the secondary structures
