When does lysosomal storage disease occur?

True or false: most lysosomal storage diseases are autosomal dominant.

Define heterophagy and state three ways in which it may occur.

Define autophagy.

What is the structure of a lysosome? What do they contain and what is their pH?

What are the enzymes found in lysosomes?

Where are the enzymes sythesised and activated?

How is the lysosome protected from degradation?

What is I cell disease?

What is the function of phagocytosis? Name three occasions it is used by cells.

Explain the 5 steps of phagocytosis.

Name a pathogen that inhibits phagosome from fusing with lysosome.

Name a pathogen where bacteria are resistant to lysosomal enzymes and acid.

Name a pathogen where the pathogen damages the lysosome membrane and escapes back into cytosol.

What is the function of receptor-mediated endocytosis?

What are the four things involved in receptor mediated endocytosis?

how is a ligand-receptor complex internalised in receptor mediated endocytosis?

True or false: a clathrin lattice covers the cytosolic face of the coated pit.

What is the function of Adaptin in receptor mediated endocytosis?

What is the main function of clathrin in receptor mediated endocytosis?

What is the function of dynamin in Receptor mediated endocytosis?

What is the function of chaperones in receptor mediated endocytosis?

Give two examples of receptor mediated endocytosis.

What is an early endosome?

What is the function of the early endosome?

What difference is there in the action of endosomes in iron transport?

True or false: viruses exploit receptor mediated endocytosis.

What is taken in during pinocytosis?

What is cell rejuvination?

When is autophagy upregulated?

Steps in autophagy. Go.

What is autolysis?

How does extracellular digestion occur? Give an example.

What is Tay-Sachs disease a deficiency in?

What is the normal function of B-N-acetylhexosaminidase? What is the result of this?