Enoxaparin sodium

Frage	Antworten
Therapeutic class	Anticoagulant
Pharmaceutical class	Low molecular weight heparin
Indications	- Prevention of VTE in surgical or bed-bound med patients - treatment for DVT and PE - Treatment of acute STEMI and non-STEMI as well as unstable angina
Action	Inactivates clotting factors thrombonin and Xa by binding to antithrombonin III
Absorption	Well-absorbed subcut
Distribution	Does not cross the placenta or enter breast milk
Metabolism & excretion	Metabolised by the liver and excreted by the kidneys in urine
Half-life	4.5 hrs
Contraindications/precautions	- caution in renally impaired - Hepatic impairment - Elderly may require dose adjustment - Those at risk of bleeding
Adverse reactions	CVS: brusing and bleeding CNS: pain at the inject. site May cause hyperkalemia, HAEMO: can cause irreversible thrombocytopenia
Interactions	When used in conjunction with other anticoagulants can increase potency
Nursing assessment implications	- Liver & renal function - Electrolyte balance - Post administration clotting factor blood tests
Education	Ask patient to advise if they notice any unexplained bleeding or bruising May require self-admin education if prolonged post-discharge use is required

Zusammenfassung der Ressource

	Erstellt von Em J vor fast 6 Jahre