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| Frage | Antworten |
| There are three categories of genes that may be involved in the causation of cancer | Oncogenes; Tumour suppressor genes; Modifying genes |
| oncogenes | growth stimulating genes |
| Tumour suppressor genes | are growth inhibitory genes |
| Modifying genes | broad spectrum of functions, alleles of which can modify the individual predisposition to cancer |
| suicide gene therapy | toxic substances incorporated into DNA during synthesis leading to fragmentation |
| Oncolytic viruses | Viruses that replicate selectively in cancer cells vs normal cells Cancer cells inactivate interferon pathway or mutate tumour suppressor genes, enabling viral replication to proceed When they replicate, they lyse host cells |
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