Lecture 2: Properties of solids

True or False:
crystalline solids are made up of repeating lattice units called unit cells

Amorphous solids have a regular repeating arrangement of molecules in their structure
True or False?

What does crystal habit describe?

What effects that are important to pharmaceutics can crystal habit have?

What do we mean by polymorphism of a drug

What is one technique we can use to detect polymorphism of a drug?

What effect can polymorphism of a drug have?

In general, if you have a hydrate form of a drug and an anhydrous form (anhydrate) which will be more soluble?

If you had a crystalline form of drug and an amorphous form of the same drug, which would usually be more soluble?

True or False
co-crystals are two crystals of same drug joined together

True or False
A polymer consists of repeating units of small molecules called monomers

Properties of polymers will vary with MW e.g. PEG 400 is liquid and PEG3350 is a solid

Why would a drug be prepared as a solid dispersion?

Explain what happens when we have a simple eutectic mixture

Give an example of a eutectic mixture