Intrauterine asphyxia

Asphyxia

Perinatal asphyxia

Hypoxia

Hypoxemia

Ischemia

4 criteria for asphyxia

Prenatal/Maternal
Risk Factors for Asphyxia

Fetal
Risk Factors for Asphyxia

Intrapartum
Risk Factors for Asphyxia

Mechanisms of Asphyxia

ultimate death of the cell is from a combination of all of these effects

Fetal Response to Hypoxia/Ischemia:
Early

Fetal Response to Hypoxia/Ischemia:
Intermediate

Fetal Response to Hypoxia/Ischemia:
Late

Fetal Response to Hypoxia/Ischemia:
Physiologic adaptation

Clinical Presentation/Recognition of Asphyxiated Infant

Complications of Asphyxia:
Cardiovascular

Complications of Asphyxia:
Pulmonary

Complications of Asphyxia:
Renal

Complications of Asphyxia:
Metabolic

Complications of Asphyxia:
Gastrointestinal

Complications of Asphyxia:
Hepatic

Complications of Asphyxia:
Hematology

Complications of Asphyxia:
Central Nervous System:
Seizures

Complications of Asphyxia:
Central Nervous System:
Cerebral edema

Complications of Asphyxia:
Central Nervous System:
Selective neuronal necrosis

Complications of Asphyxia:
Central Nervous System:
Parasagittal neuropathy

Complications of Asphyxia:
Central Nervous System:
Status marmoratus of basal ganglia or thalamus

Complications of Asphyxia:
Central Nervous System:
Focal or multifocal necrosis

Complications of Asphyxia:
Central Nervous System:
Periventricular leukomalacia

Management and Therapies:
General

Management and Therapies:
Cardiovascular

Management and Therapies:
Pulmonary

Management and Therapies:
Pulmonary
cont'd

Management and Therapies:
Renal

Management and Therapies:
Metabolic

Management and Therapies:
Gastrointestinal and Hepatic

Management and Therapies:
Hematology

Management and Therapies:
Central Nervous System

Experimental Agents