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Quiz by Matthew Coulson, created more than 1 year ago

Intro To Haematology & Normal Red Cells 2 lectures in this one quiz

	Created by Matthew Coulson about 5 years ago

Intro To Haematology & Normal Red Cells

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Question 1 of 37

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Between months 3-7 of pregnancy, the foetus uses which organ to conduct haematopoiesis?
The

Explanation

Question 2 of 37

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A Multipotent Haematopoietic Stem Cell (Hemocystblast) can differentiate to form two types of common progenitor stem cells:
The Common Progenitor, which goes on to form such cells as neutrophils, basophils and erythrocytes.
The Common Progenitor, which goes on to form such cells as natural killer cells, B cells and T cells.

Explanation

Question 3 of 37

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An erythrocyte is another term for a .
Erythrocytes arise from Common Progenitor Cells

Explanation

Question 4 of 37

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During erythropoiesis, the late normoblast matures by losing which of its internal structures?
Its

Explanation

Question 5 of 37

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Immature, non-nucleated red blood cells are called

Explanation

Question 6 of 37

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A is a large bone marrow cell with a lobulated nucleus which is responsible for the production of platelets

Explanation

Question 7 of 37

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Megakaryocytes (and thus platelets) arise from common progenitor cells.

Explanation

Question 8 of 37

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Name the three types of granulocytes in alphabetical order

Explanation

Question 9 of 37

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( Neutrophils, Eosinophils, Basophils ) - Granulocytes with polymorphic (multiple) nuclei
( Eosinophils, Neutrophils, Basophils ) - Granulocytes with bi-lobed nucleus
( Basophils, Neutrophils, Eosinophils ) - Granulocytes with large deep purple granules obscuring the nucleus

Explanation

Question 10 of 37

Name the granulocytes.

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Neutrophil

Eosinophil

Basophil

Explanation

Question 11 of 37

Click on the orange point and write the correct answer.

What is this cell type? Hint: Note the vacuoles.

Explanation

Question 12 of 37

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Monocytes circulate in the blood for around a week before entering tissues to become

Explanation

Question 13 of 37

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Which bony aspect of the hip is the most common site for bone marrow aspiration?
The

Explanation

Question 14 of 37

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Which aspect of the iliac crests, anterior or posterior, is the most common site for bone marrow aspiration?
The Iliac Crests

Explanation

Question 15 of 37

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A bone marrow biopsy is also commonly called a biopsy due to the surgical instrument used to conduct the procedure, which has a cylindrical saw used for removing a disk of bone.

Explanation

Question 16 of 37

Red blood cells have large, single nuclei.

Select one of the following:

True
False

Explanation

Question 17 of 37

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Adult Haemoglobin consists of two ( alpha, delta ) chains and two ( beta, gamma ) chains

Explanation

Question 18 of 37

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Foetal Haemoglobin consists of two ( alpha, delta ) chains and two ( gamma, beta ) chains

Explanation

Question 19 of 37

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( Gamma, Alpha, Beta, Delta ) chains allow a higher affinity for oxygen as they do not interact as well with 2,3-DPG

Explanation

Question 20 of 37

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( Fe3+, Fe2+ ) = Oxidised form of iron
( Fe2+, Fe3+ ) = Reduced (non-oxidised) form of Iron

Explanation

Question 21 of 37

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The form of iron that exists in the Heme group is the ( non-oxidised, oxidised ) ( Fe2+, Fe3+ ) form

Explanation

Question 22 of 37

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Red Blood Cell destruction occurs in which organ?
The

Explanation

Question 23 of 37

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The heme group of the red blood cell is broken down by the spleen into Iron and

Explanation

Question 24 of 37

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Which organ conjugates bilirubin?
The

Explanation

Question 25 of 37

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Bilirubin is excreted within which substance, which gives colour to both urine and faeces?
The

Explanation

Question 26 of 37

Heme breakdown pathway:
Heme --> ❌ --> ❌ --> ❌

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Porphyrin

Biliverdin

Unconjugated Bilirubin

Explanation

Question 27 of 37

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Which hormone regulates the differentiation and proliferation of erythroid progenitor cells in the bone marrow to mature red blood cells?

Explanation

Question 28 of 37

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Erythropoietin is produced mainly in the

Explanation

Question 29 of 37

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Methemoglobin is the non-oxygen carrying type of haemoglobin in which the heme groups contains the ( oxidised, non-oxidised ) ( Fe3+, Fe2+ )

Explanation

Question 30 of 37

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Superoxide to Hydrogen Peroxide is regulated by which enzyme?

Explanation

Question 31 of 37

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Which antioxidant reacts with Hydrogen Peroxide to form water, in order to protect us against the free radical?

Explanation

Question 32 of 37

CO2 Transport:
10% ❌
30% ❌
60% ❌

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Travels as Bicarbonate

Bound directly to Hb

Dissolved in solution

Explanation

Question 33 of 37

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( Myoglobin, Haemoglobin ) follows Michaelis-Menten Kinetics
( Haemoglobin, Myoglobin ) DOES NOT follow Michaelis-Menten Kinetics

Explanation

Question 34 of 37

The product of the Rapapoport-Lubering Shunt is ...

Select one of the following:

2,3-DPG
Glutathione
Pentose Phosphate
Hexose Monophosphate
Glyceraldehyde-3-Phosphate

Explanation

Question 35 of 37

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As 2,3-DPG concentration increases, the rate of oxygen dissociation ( increases, decreases ) as the affinity of haemoglobin for oxygen ( decreases, increases ).

Explanation

Question 36 of 37

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The causes of a right shift to the Oxygen–hemoglobin dissociation curve:
( Increase, Decrease ) in CO2 concentration
( Decrease, Increase ) in pH
( Increase, Decrease ) in 2,3-DPG concentration
( Increase, Decrease ) in Exercise
( Increase, Decrease ) in Temperature

Explanation

Question 37 of 37

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Glutathione is replenished by which chemical? Hint: It is a normal part of glycolysis

Explanation

Intro To Haematology & Normal Red Cells 2 lectures in this one quiz

Intro To Haematology & Normal Red Cells

Intro To Haematology & Normal Red Cells

Question 1 of 37

Fill the blank space to complete the text.

Between months 3-7 of pregnancy, the foetus uses which organ to conduct haematopoiesis? The

Explanation

Question 2 of 37

Fill the blank spaces to complete the text.

Explanation

Question 3 of 37

Fill the blank spaces to complete the text.

An erythrocyte is another term for a . Erythrocytes arise from Common Progenitor Cells

Explanation

Question 4 of 37

Fill the blank space to complete the text.

During erythropoiesis, the late normoblast matures by losing which of its internal structures? Its

Explanation

Question 5 of 37

Fill the blank space to complete the text.

Immature, non-nucleated red blood cells are called

Explanation

Question 6 of 37

Fill the blank space to complete the text.

A is a large bone marrow cell with a lobulated nucleus which is responsible for the production of platelets

Explanation

Question 7 of 37

Fill the blank space to complete the text.

Megakaryocytes (and thus platelets) arise from common progenitor cells.

Explanation

Question 8 of 37

Fill the blank spaces to complete the text.

Name the three types of granulocytes in alphabetical order

Explanation

Question 9 of 37

Select from the dropdown lists to complete the text.

Explanation

Question 10 of 37

Name the granulocytes.

Drag an answer into the correct orange point.

Explanation

Question 11 of 37

Click on the orange point and write the correct answer.

What is this cell type? Hint: Note the vacuoles.

Explanation

Question 12 of 37

Fill the blank space to complete the text.

Monocytes circulate in the blood for around a week before entering tissues to become

Explanation

Question 13 of 37

Fill the blank space to complete the text.

Which bony aspect of the hip is the most common site for bone marrow aspiration? The

Explanation

Question 14 of 37

Fill the blank space to complete the text.

Which aspect of the iliac crests, anterior or posterior, is the most common site for bone marrow aspiration? The Iliac Crests

Explanation

Question 15 of 37

Fill the blank space to complete the text.

A bone marrow biopsy is also commonly called a biopsy due to the surgical instrument used to conduct the procedure, which has a cylindrical saw used for removing a disk of bone.

Explanation

Question 16 of 37

Red blood cells have large, single nuclei.

Select one of the following:

Explanation

Question 17 of 37

Select from the dropdown lists to complete the text.

Adult Haemoglobin consists of two alpha delta( alpha, delta ) chains and two beta gamma( beta, gamma ) chains

Explanation

Question 18 of 37

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Foetal Haemoglobin consists of two alpha delta( alpha, delta ) chains and two gamma beta( gamma, beta ) chains

Explanation

Question 19 of 37

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Gamma Alpha Beta Delta( Gamma, Alpha, Beta, Delta ) chains allow a higher affinity for oxygen as they do not interact as well with 2,3-DPG

Explanation

Question 20 of 37

Select from the dropdown lists to complete the text.

Fe3+ Fe2+( Fe3+, Fe2+ ) = Oxidised form of iron Fe2+ Fe3+( Fe2+, Fe3+ ) = Reduced (non-oxidised) form of Iron

Between months 3-7 of pregnancy, the foetus uses which organ to conduct haematopoiesis?
The

An erythrocyte is another term for a .
Erythrocytes arise from Common Progenitor Cells

During erythropoiesis, the late normoblast matures by losing which of its internal structures?
Its

Which bony aspect of the hip is the most common site for bone marrow aspiration?
The

Which aspect of the iliac crests, anterior or posterior, is the most common site for bone marrow aspiration?
The Iliac Crests

Adult Haemoglobin consists of two ( alpha, delta ) chains and two ( beta, gamma ) chains

Foetal Haemoglobin consists of two ( alpha, delta ) chains and two ( gamma, beta ) chains

( Gamma, Alpha, Beta, Delta ) chains allow a higher affinity for oxygen as they do not interact as well with 2,3-DPG

( Fe3+, Fe2+ ) = Oxidised form of iron
( Fe2+, Fe3+ ) = Reduced (non-oxidised) form of Iron

The form of iron that exists in the Heme group is the ( non-oxidised, oxidised ) ( Fe2+, Fe3+ ) form

Red Blood Cell destruction occurs in which organ?
The

Which organ conjugates bilirubin?
The

Bilirubin is excreted within which substance, which gives colour to both urine and faeces?
The

Heme breakdown pathway:
Heme --> ❌ --> ❌ --> ❌

Methemoglobin is the non-oxygen carrying type of haemoglobin in which the heme groups contains the ( oxidised, non-oxidised ) ( Fe3+, Fe2+ )

CO2 Transport:
10% ❌
30% ❌
60% ❌

( Myoglobin, Haemoglobin ) follows Michaelis-Menten Kinetics
( Haemoglobin, Myoglobin ) DOES NOT follow Michaelis-Menten Kinetics

As 2,3-DPG concentration increases, the rate of oxygen dissociation ( increases, decreases ) as the affinity of haemoglobin for oxygen ( decreases, increases ).