Psychopharmacology A

Typical Anti-Psychotics

Atypical (second generation) Anti-Psychotics

Drug’s half-life

Elimination

(Half Life)

Clearance

(Half Life)

Volume of Distribution

(Half Life)

Steady State

(Half Life)

Time taken to reach steady state

Aripiprazole Half Life

Clozapine Half Life

Olanzapine Half Life

Risperidone Half Life

Quetiapine Half Life

Amisulpride Half Life

Olanzapine therapeutic dosage range

Schizophrenia

Risperidone Therapeutic Dosage Range

Schizophenia

Aripiprazole Therapeutic
Dosage Range

Clozapine Therapeutic
Dosage Range

reasons for blood monitoring in atypical anti-psychotics (generally)

Clozapine and the continued blood monitoring testing necessary when on medication and the reasons for this

Extrapyramidal Side-effects (EPS): Cause,
Types, Clinical features

Main brain region implicated for EPS

Sexual side-effects of anti-psychotics

Signs and symptoms of Neuroleptic Malignant Syndrome (NMS)

Anticholinergic (Antimuscarinic) medications used for control of EPS

Side effects of Anticholinergic (Antimuscarinic) medications

Tools that monitor side-effects of antipsychotic medication

Advantages of Atypical anti-psychotics over Typical antipsychotics

Concordance Definition

Concordance Process

Concordance Key Therapeutic Skills

Adherence

Non-Adherence

Non-Adherence Factors

Non-Adherence 5 main factors + summary

Interventions to enhance Adherence / Concordance

Concordance Tips for Practice

NMC (2010) Standards for Medicines Management:
Section 9 (Standard 24): Management of Adverse Events (1)

NMC (2010) Standards for Medicines Management:
Section 9 (Standard 24): Management of Adverse Events (2) (Process)

NMC (2010) Standards for Medicines Management:
Section 9 (Standard 25) Reporting Adverse Reactions

Yellow Card Scheme (Medicines and Healthcare Products Regulatory Agency-MHRA) – rationale, level of usage issues