gina_evans0312
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Year 2 Quiz on PIP2 Pathway, created by gina_evans0312 on 11/04/2013.

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PIP2 Pathway

PIP2 Pathway

Question 1 of 8

1

Once tyrosine kinase is activated, which protein binds?

Select one of the following:

  • Phospholipase Cgamma

  • Phospholipase Cdelta

  • Phospholipase Calpha

Explanation

Question 2 of 8

1

How does tyrosine kinase activate phospholipase cX?

Select one of the following:

  • No, really, how'd you think? What else could it POSSIBLY BE

  • Phosphorylation

Explanation

Question 3 of 8

1

What is the function of Phospholipase Cgamma?

Select one of the following:

  • PIP3 breakdown

  • PIP2 breakdown

  • PIP breadown

Explanation

Question 4 of 8

1

What happens to phospholipase cX when it binds to T.K?

Select one of the following:

  • It is phosphorylated

  • It's dephosphorylated

Explanation

Question 5 of 8

1

Name the products of PIP breakdown

Select one or more of the following:

  • IP3

  • DAG

  • No seriously, how many times have we covered this protein family?

Explanation

Question 6 of 8

1

What subunit allows Phospholipase Cgamma to be recruited to the phosphorylated tyrosine kinase?

Select one of the following:

  • SH3

  • SH2

  • SH4

Explanation

Question 7 of 8

1

Most of the phospholipase cgamma's effects are the same as phospholipase Cbeta, which one is different?

Select one of the following:

  • PKC activation causes the activation of Na+/H+ pumps

  • PKC activation causes the activation of Na+/K+ pumps

  • PKC activation causes the activation of Na+/Cl- pumps

Explanation

Question 8 of 8

1

What is the effect of the membrane pump activation?

Select one or more of the following:

  • Cell becomes more alkaline

  • Cell becomes more acidic

  • Cell prepares for mitosis

Explanation

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