Section A questions

how do we manipulate siRNA to make useful in theraputics

why are scientists interested in recombinant and DNA vaccines

why should we consider transplantation as gene therapy

what are the main issues when using stem cells for theraputics

what types of vectors are used in gene augmentation therapy?- usually use

what types of vectors are used in gene augmentation therapy?- can also use use

outline the types of molecules used in gene silencing

anti sense molecules

triple helices

ribozymes

what are the properties of vectors that are important in gene therapy

what is a cybrid?

cybrid

what are the problems associated with the use of theraputic recombinant proteins

outline the genetic modifications of transgenic pigs engineered for xenotransplantation

list with examples the types of molecular therapies available for the treatment of cancer (5)

differentiate between reproductive and theraputic stem cell therapy

list the problems associated with the use of monoclonal antibodies (5)

list problems associated w/production of mAB

what are the properties of vectors that are important in human gene therapy (8)

list the types of recombinant proteins that may be used in theraputic strategies + examples (6)

C/C two methods of producing transgenic animals- ES cells

C/C transgenic animal production-direct injection

list with examples the types of molecular therapies available for the treatment of inherited diseases (8)

briefly describe the types of vaccines used in humans

list the problems associated with production of a recombinant theraputic protein (9)

vectors for human gene therapy-viruses

vectors for human gene therapy- non viral

list the problems associated with using human organs for transplant

list the problems associated with using animal organs for transplant