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Blood MCQs

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  • Blood MCQs Physiology PMU 2nd Year

    Question 1 of 97

    1

    Blood clotting:

    Select one of the following:

    • requires Ca2+

    • is promoted by erythrocytes

    • defects usually prolong the bleeding time

    • is initiated by tissue tromboplastin in the intrinsic coagulation pathway

    • is decreased by platelets

    Question 2 of 97

    1

    B-lymphocytes:

    Select one of the following:

    • secrete circulating antibodies

    • carry antigen receptors on their surface

    • secrete antigens

    • secrete IGF-1

    • secrete fibrinogen

    Question 3 of 97

    1

    Red blood cells:

    Select one of the following:

    • measure 15 mm in diameter

    • do not contain mitochondria

    • have a life span in circulation of 30 days

    • are released from the bone marrow as mature cells

    • contain nucleus

    Question 4 of 97

    1

    The following is true about the ABO and Rh systems

    Select one of the following:

    • A person of group O is a universal recipient

    • A person who is group AB has anti-A and anti-B antibodies

    • The presence of D antigen means that the subject is Rh(+)

    • Rh antibodies occur naturally

    • The person of group A has anti-A antibodies

    Question 5 of 97

    1

    Which of the following helps in blood clotting?

    Select one of the following:

    • Vit. B1

    • Vit. B2

    • Vit. D

    • Vit. K

    • Vit. B6

    Question 6 of 97

    1

    The function of hemoglobin is:

    Select one of the following:

    • Transport of oxygen

    • Destruction of bacteria

    • Prevention of anaemia

    • Utilization of energy

    • Transport of CO

    Question 7 of 97

    1

    Which of the following substances is an anticoagulant?

    Select one of the following:

    • Ca2+

    • Heparin

    • Fibrinogen

    • Albumin

    • Gamma-Globulins

    Question 8 of 97

    1

    What are the agglutinins?

    Select one of the following:

    • antibodies

    • antigens

    • beta-globulins

    • amino acids

    • lipids

    Question 9 of 97

    1

    Which of the following substance influences indirectly blood clotting?

    Select one of the following:

    • calcium ions

    • vit. K and vit. C

    • vit. B6 and vit. K

    • mineralocorticoids

    • renin

    Question 10 of 97

    1

    For which of the following cells phagocytosis is not typical?

    Select one of the following:

    • neurotrophins

    • plasmocytes

    • monocytes

    • eosinophils

    • macrophages

    Question 11 of 97

    1

    Normal (physiological) hemolysis takes place:

    Select one of the following:

    • inside the heart

    • inside the spleen and liver

    • inside the kidneys

    • inside the big blood vessels

    • inside the bone marrow

    Question 12 of 97

    1

    Which of the following are functions of the blood?

    Select one of the following:

    • transport

    • regulation

    • protection

    • temperature regulation

    • all of the above

    Question 13 of 97

    1

    The blood volume of an average size male is:

    Select one of the following:

    • 3 to 4 liters

    • 4 to 5 liters

    • 5 to 6 liters

    • 6 to 7 liters

    • 7 to 9 liters

    Question 14 of 97

    1

    The blood volume is:

    Select one of the following:

    • 10-12% of body weight

    • 10l

    • 6-8% of body weight

    • 5l

    • 3-5% of body weight

    Question 15 of 97

    1

    The effects on plasma volume of 500 ml blood loss are neutralized within:

    Select one of the following:

    • 1-2 hours

    • 8-10 hours

    • 24 hours

    • one week

    • one month

    Question 16 of 97

    1

    Antithrombin III affects which coagulation factor?

    Select one of the following:

    • XIIa

    • Xa

    • IIa

    • IXa

    • all of the above

    Question 17 of 97

    1

    Vitamin K neutralizes:

    Select one of the following:

    • factor 5

    • heparin

    • antithrombin 3

    • plasminogen

    • none of the above

    Question 18 of 97

    1

    Platelet activation will not occur without:

    Select one of the following:

    • Ca2+

    • Vessel wall damage

    • Von Willebrand factor

    • Fibrinogen

    • Serotonin

    Question 19 of 97

    1

    Complement activation requires:

    Select one of the following:

    • antigen-antibody complex

    • opsonization of bacteria

    • helper T-Cells

    • previous exposure to antigen

    • plasma proteins

    Question 20 of 97

    1

    For a T-cell to recognize a foreign antigen:

    Select one of the following:

    • opsonization

    • the antigen presenting cell identifies the antigen

    • needs T-helper cells

    • prior exposure to antigen required

    • none of the above

    Question 21 of 97

    1

    Hemoglobin contains:

    Select one of the following:

    • one protoporphyrin ring and four ferrous ions

    • four protoporphyrin ring and one ferrous ion

    • four protoporphyrin rings and four ferrous ions

    • one protoporphyrin ring and one ferrous ion

    • none of the above

    Question 22 of 97

    1

    Which blood component plays the biggest role in maintaining the osmotic pressure of blood?

    Select one of the following:

    • albumin

    • carbon dioxide

    • white blood cells

    • fibrinogen

    • globulins

    Question 23 of 97

    1

    In a normal blood sample, which of the following cells will be the most abundant?

    Select one of the following:

    • neutrophils

    • basophiles

    • eosinophiles

    • monocytes

    • lymphocytes

    Question 24 of 97

    1

    An antigen:

    Select one of the following:

    • A chemical messenger that is released by virus infected cells

    • A lymphocyte responsible for cell-mediated immunity

    • Something that coats the inside of lungs, causing infection

    • A protein or other molecule that is recognized as non-self

    • A thick yellow-white fluid

    Question 25 of 97

    1

    Where is the site of maturation for a B-cell?

    Select one of the following:

    • thymus

    • bone marrow

    • pancreas

    • cortex

    • spleen

    Question 26 of 97

    1

    Nonspecific resistance is:

    Select one of the following:

    • the body's ability to ward off diseases

    • the body's defenses against any kind of pathogen

    • the body's defense against a particular pathogen

    • the lack of resistance

    • none of the above

    Question 27 of 97

    1

    Which gland shrinks in size during adulthood, and has hormones that function in the maturation of T-lymphocytes:

    Select one of the following:

    • lymph nodes

    • thymus

    • spleen

    • pineal gland

    • tonsils

    Question 28 of 97

    1

    The rate of erythrocyte sedimentation is increased when:

    Select one of the following:

    • the plasma albumin fraction is increased

    • fibrinogen in the blood is decreased

    • the plasma globulin fraction is decreased

    • the plasma globulin fraction is increased

    • lack of erythropoietin

    Question 29 of 97

    1

    Agglutinins are found in:

    Select one of the following:

    • the erythrocytes membrane

    • the leukocytes

    • the plasma

    • the platelets

    • all of the above

    Question 30 of 97

    1

    γ-globulins are related to:

    Select one of the following:

    • Humoral Immunity

    • Blood Coagulation

    • Transport of gases by the blood

    • Erythropoiesis

    • Cellular Immunity

    Question 31 of 97

    1

    Oxyhemoglobin is a compound of:

    Select one of the following:

    • hemoglobin and 02

    • hemoglobin and CO2

    • hemoglobin and Fe2+

    • hemoglobin and CO

    • hemoglobin and N

    Question 32 of 97

    1

    The amount of plasma proteins is:

    Select one of the following:

    • 135-145 mmol.1-1

    • 140-160 g.1-1

    • 55-85 g.1-1

    • 2.8-5.6 mmol.1-1

    • 0.40-0.50 1.1-1

    Question 33 of 97

    1

    The plasma of blood type AB contains:

    Select one of the following:

    • anti-A agglutinins

    • anti-B agglutinins

    • anti-A and anti-B agglutinins

    • no agglutinins

    • agglutinogens A and B

    Question 34 of 97

    1

    Osmotic hemolysis is due to:

    Select one of the following:

    • water hypotonic solution entering the erythrocytes

    • destruction of the erythrocyte membrane by chemicals

    • fibrinolysis

    • formation of carbaminohemoglobin

    • transformation of fibrinogen into fibrin

    Question 35 of 97

    1

    Hypervolemia is:

    Select one of the following:

    • increased blood volume

    • decreased blood volume

    • increased blood cholesterol

    • increased plasma proteins

    • increased blood pressure

    Question 36 of 97

    1

    Leucopenia is:

    Select one of the following:

    • increased number of leukocytes

    • increased number of platelets

    • decreased number of leucocytes

    • increased number of erythrocytes

    • decreased number of platelets

    Question 37 of 97

    1

    When AB(0) blood is transfused to a recipient of blood type 0 (anti-A, anti-B):

    Select one of the following:

    • the limit of the blood transfused is up to 300 ml

    • the transfused amount is unlimited

    • transfusion is forbidden

    • transfusion of plasma is the only possibility

    • possible only once in a lifetime

    Question 38 of 97

    1

    Sodium citrate stops coagulation by:

    Select one of the following:

    • blocking fibrinogen

    • reacting with Ca2+

    • massive fibrinolysis

    • destruction of platelets

    • blocking Vit. K

    Question 39 of 97

    1

    The normal erythrocyte count is:

    Select one of the following:

    • 140-160.10^9.1-1

    • 4-5.2.10^12.1-1

    • 4-11.10^9.1-1

    • 200-400.10^9.1-1

    • 0.40-0.50 1.1-1

    Question 40 of 97

    1

    Leucocytosis is:

    Select one of the following:

    • increased number of leukocytes

    • increased number of platelet

    • decreased number of leucocytes

    • increased number of erythrocytes

    • increased percentage of neutrophils

    Question 41 of 97

    1

    Platelets take part in:

    Select one of the following:

    • the immune defense

    • the transport of gases in blood

    • homeostasis

    • renin-angiotensin-aldosterone system

    • all of the above

    Question 42 of 97

    1

    The normal values of hemoglobin are:

    Select one of the following:

    • 4-5.5.10^12.1-1

    • 135-145 mmol.1-1

    • 140-160 g.1-1

    • 2.8-5.6 mmol.1-1

    • 140-160 g%

    Question 43 of 97

    1

    Of major significance for maintaining the blood oncotic pressure is:

    Select one of the following:

    • the number of erythrocytes

    • the plasma globulin fraction

    • the leukocyte count

    • the plasma albumin fraction

    • the plasmafibrinogen

    Question 44 of 97

    1

    The red color of blood is due to:

    Select one of the following:

    • The plasma cholesterol

    • The plasma albumin fraction

    • Ca2+ and K+ in plasma

    • The granules in the leucocytes

    • The hemoglobin in the erythrocytes

    Question 45 of 97

    1

    The normal blood platelet count is:

    Select one of the following:

    • 4-11.10^9.1-1

    • 4.4-5.2 10^12.1-1

    • 60-90.10^12.1-1

    • 200-400.10^9.1-1

    • 200-400.10^12.1-1

    Question 46 of 97

    1

    Fibrinolysis is:

    Select one of the following:

    • Formation of the white plug

    • Formation of the red plug

    • Fibrin clot destruction

    • Viscose metamorphosis of the platelets

    • Destruction of adrenal medulla

    Question 47 of 97

    1

    When blood is transfused from 0(anti-A, anti-B) donor to AB(0) recipient:

    Select one of the following:

    • the amount is up to 500 ml

    • the amount is unlimited

    • transfusion is impossible

    • only plasma may be transfused

    • only once in a lifetime

    Question 48 of 97

    1

    The osmotic fragility is determined by the use of:

    Select one of the following:

    • Hypotonic solution of NaCl

    • Hypertonic solution of NaCl

    • HCl

    • NaOH

    • Celloscope

    Question 49 of 97

    1

    Heparin is:

    Select one of the following:

    • a factor transforming prothrombin into thrombin

    • platelet factor 8

    • endogenic anticoagulant

    • exogenic anticoagulant

    • pancreatic enzyme

    Question 50 of 97

    1

    The plasma protein fraction of major significance for coagulation is:

    Select one of the following:

    • albumin

    • globulin

    • fibrinogen

    • γ-globulin

    • globulin and albumin

    Question 51 of 97

    1

    The normal range of the erythrocyte sedimentation rate (Westergren) is:

    Select one of the following:

    • 2.4-2.6 mmol.1-1

    • 140-160 g.1-1

    • 1st hour: men- 3-8 mm; women- 5-10 mm

    • 0.55-1.48 g.1-1

    • 0.40-0.50 1.1-1

    Question 52 of 97

    1

    Of major significance for the erythrocyte sedimentation rate is:

    Select one of the following:

    • the leukocyte count

    • the albumin/globulin ratio

    • total blood cholesterol

    • the platelet count

    • the leukocytes ratio (%)

    Question 53 of 97

    1

    The normal leukocyte count is:

    Select one of the following:

    • 200-400.10^9.1-1

    • 4.0-11.10^9.1-1

    • 4.5-5.2.10^12.1-1

    • 60-90.10^9.1-1

    • 20-40% of all blood cells

    Question 54 of 97

    1

    Fe2+ ions are necessary for:

    Select one of the following:

    • the production of fibrinogen

    • erythropoiesis

    • the formation of leukocytes

    • the formation of platelets

    • the synthesis of thyreocalcitonin

    Question 55 of 97

    1

    The percentage of Rh(+) people is:

    Select one of the following:

    • 15%

    • 85%

    • 50%

    • 30%

    • 15% of pregnant women

    Question 56 of 97

    1

    The normal hematocrit range in men is:

    Select one of the following:

    • 0.40-0.50 1.1-1

    • 2.4-2.6 mnol.1-1

    • 0.55-1.48 mmol.1-1

    • 140 - 160 g.1-1

    • 4.5-5.5.10^12.1-1

    Question 57 of 97

    1

    Hematocrit measures the percentage of:

    Select one of the following:

    • white blood cells

    • plasma

    • platelets

    • red blood cells

    • serum proteins

    Question 58 of 97

    1

    To prevent blood loss after a tissue injury, blood vessels first:

    Select one of the following:

    • form a platelet plug

    • form a clot

    • initiate the coagulation cascade

    • constrict and form barriers

    • dilate

    Question 59 of 97

    1

    A foreign substance, usually a protein, that stimulates the immune system to react by producing antibodies is called:

    Select one of the following:

    • allergen

    • antigen

    • histamine

    • mast cell

    • interferon

    Question 60 of 97

    1

    When neutrophils and macrophages squeeze out of capillaries to fight off infection, it is called:

    Select one of the following:

    • phagocytosis

    • hemolysis

    • interleukin

    • diapedesis

    • folliculitis

    Question 61 of 97

    1

    Each of the following is a component of plasma except:

    Select one of the following:

    • water

    • proteins

    • formed elements

    • nutrients

    • salts

    Question 62 of 97

    1

    Extracellular fluid in adults differs from intracellular fluid in that its:

    Select one of the following:

    • volume is greater

    • tonicity is lower

    • Na+ concentration is lower

    • sodium: potassium molar ratio is higher

    • pH is lower

    Question 63 of 97

    1

    Total body water, expressed as a percentage of body weight:

    Select one of the following:

    • can be measured with an indicator dilution technique to deuterium oxide

    • is smaller on average in women than in men

    • rises following injection of posterior pituitary extracts

    • is less than 80 per cent in young adults

    • all of the above

    Question 64 of 97

    1

    Breakdown of erythrocytes in the body:

    Select one of the following:

    • occurs when they are 6-8 weeks old

    • is named erythropoiesis

    • yields iron, most of which is excreted in the urine

    • yields bilirubin which is carried by plasma protein to the liver

    • is required for the synthesis of bile salts

    Question 65 of 97

    1

    A person with group A blood

    Select one of the following:

    • has anti-A antibody in the plasma

    • may have the genotype AB

    • may have a parent with group O blood

    • may have children with group A or group O blood only

    • whose partner is also A can only have children of group A

    Question 66 of 97

    1

    Blood platelets are:

    Select one of the following:

    • releasing factors promoting blood clotting

    • adhering together to form plugs when exposed to collagen

    • 200-400.10^9.1^-1

    • releasing factors causing vasoconstriction

    • all of the above

    Question 67 of 97

    1

    Plasma bilirubin:

    Select one of the following:

    • is a steroid pigment

    • is converted to biliverdin in the liver

    • does not normally cross cerebral capillary walls

    • is freely filtered in the renal glomerulus

    • has red colour

    Question 68 of 97

    1

    Monocytes:

    Select one of the following:

    • originate from precursor cells in lymph nodes

    • can Increase in number when their parent cells are stimulated by factors released from activated lymphocytes

    • unlike granulocytes, do not migrate across capillary walls

    • take part in homeostasis

    • manufacture immunoglobulin M

    Question 69 of 97

    1

    Erythrocytes:

    Select one of the following:

    • are responsible for the major part of blood viscosity

    • contain the enzyme carbonic anhydrase

    • metabolize glucose to produce CO2 and H2O

    • carry 02 and CO2

    • all of the above

    Question 70 of 97

    1

    Human plasma albumin:

    Select one of the following:

    • contributes more to plasma colloid osmotic pressure than globulin

    • can not filter freely at the glomerulus

    • is negatively charged at the normal pH of blood

    • carries sex hormones in blood

    • all of the above

    Question 71 of 97

    1

    Neutrophil granulocytes:

    Select one of the following:

    • are the most common leukocyte in normal blood

    • contain proteolytic enzymes

    • contain actin and myosin microfilaments

    • are present in high concentration in pus

    • all of the above

    Question 72 of 97

    1

    Bleeding from a small cut in the skin:

    Select one of the following:

    • is normally diminished by local vascular spasm

    • ceases within about five minutes in normal people

    • is greater from warm skin than from cold skin

    • is reduced if the affected limb is elevated

    • all of the above

    Question 73 of 97

    1

    Circulating red blood cells:

    Select one of the following:

    • are about 1 per cent nucleated

    • take part in immunity

    • are distributed evenly across the blood stream in large blood vessels

    • deform as they pass through the capillaries

    • travel at slower velocity in venules than in capillaries

    Question 74 of 97

    1

    Lymphocytes:

    Select one of the following:

    • are motile

    • can transform into plasma cells

    • increase in number during infection

    • decrease in number during immunosuppressive drug therapy

    • all of the above

    Question 75 of 97

    1

    Blood:

    Select one of the following:

    • makes up about 3% of body weight

    • forms a higher percentage of body weight in fat than in thin people

    • squeezes out serum when it clots

    • volume can be calculated by multiplying plasma volume by the haematocrit (expressed as a percentage)

    • volume rises after diuretic is taken

    Question 76 of 97

    1

    The pH:

    Select one of the following:

    • of arterial blood normally ranges from 7.2 to 7.6

    • units express [H+] in moles/litre

    • of blood is directly proportional to the pCO2

    • of blood is directly proportional to [HCO3-]

    • of arterial blood is lower than venous blood

    Question 77 of 97

    1

    Blood eosinophils:

    Select one of the following:

    • have agranular cytoplasm

    • are about a quarter of all leukocytes

    • are relatively abundant in the mucosa of the respiratory, urinary and alimentary tracts

    • are 50-70% of all leukocytes

    • increase in number in viral infections

    Question 78 of 97

    1

    Lymph:

    Select one of the following:

    • doesn't contain plasma proteins

    • vessels are involved in the absorption of amino acids from the intestine

    • production decreases during muscular activity

    • does not normally contain cells

    • flow is aided by contraction of adjacent skeletal muscles

    Question 79 of 97

    1

    Blood platelets:

    Select one of the following:

    • are formed in the bone marrow

    • are normally more numerous than white cells

    • increase in number after injury and surgery

    • alter shape when in contact with collagen

    • all of the above

    Question 80 of 97

    1

    An appropriate dilution indicator for measuring:

    Select one of the following:

    • total body water is sucrose

    • plasma volume is radioactive sodium

    • extracellular fluid volume is inulin

    • intracellular fluid volume directly is heavy water (deuterium oxide)

    • total body water is radioactive iodine

    Question 81 of 97

    1

    Excessive tissue fluid (oedema) in the legs may:

    Select one of the following:

    • be associated with a raised extracellular fluid volume

    • result from hepatic disease

    • result from blockage of pelvic lymphatics

    • increase local interstitial thud pressure

    • all of the above

    Question 82 of 97

    1

    Haemolytic disease of the new born:

    Select one of the following:

    • can be prevented by injecting the mother with anti-D agglutinins just after delivery

    • affects mainly babies of Rh-positive mothers

    • occurs mainly in babies who lack D agglutinogen

    • causes jaundice which clears rapidly alter birth

    • can be treated by transfusing the affected baby with Rh-positive blood

    Question 83 of 97

    1

    Patients with moderate to severe anaemia have a reduced:

    Select one of the following:

    • cardiac output

    • incidence of vascular bruits

    • 2:3-diphosphoglycerate blood level

    • arterial pO2

    • capacity to raise oxygen consumption in exercise

    Question 84 of 97

    1

    Iron deficiency:

    Select one of the following:

    • frequently follows persistent loss of blood from the body

    • is more common in men than in women

    • may cause anaemia by inhibiting the rate of multiplication of RBC stem cells

    • may cause large pale erythrocytes to appear in peripheral blood

    • anaemia should normally be treated by injections of iron

    Question 85 of 97

    1

    Severe reactions are likely after transfusion of blood group:

    Select one of the following:

    • A to a group B person

    • O to a group AB person

    • O to a group A person

    • A to a group AB person

    • O Rh- negative to a group AB Rh-positive person

    Question 86 of 97

    1

    The haematocrit (packed cell volume):

    Select one of the following:

    • may be obtained by centrifugation of blood donation

    • may be calculated by multiplying the mean cell volume by the red cell count

    • rises in a patient who sustains widespread burns

    • rises following vomiting

    • all of the above

    Question 87 of 97

    1

    Red cell formation is increased:

    Select one of the following:

    • in blood donors one week after a blood donation

    • in patients with haemolytic anaemia

    • by giving injections of erythropoietin to nephrectomized patients

    • in patients who have a raised blood reticulocyte count

    • all of the above

    Question 88 of 97

    1

    Respiratory alkalosis differs from metabolic alkalosis in that the:

    Select one of the following:

    • patient has hyperventilation

    • arterial blood [HCO3-] is normal or low

    • arterial blood pCO2 is reduced

    • reduction in cerebral blood flow is greater

    • all of the above

    Question 89 of 97

    1

    Red blood cells would swell in which type of solution?

    Select one of the following:

    • hypotonic

    • isotonic

    • hypertonic

    • hydrophilic

    • lipophilic

    Question 90 of 97

    1

    The most abundant type of protein in plasma is:

    Select one of the following:

    • insulin

    • globulin

    • albumin

    • glycogen

    • fibrinogen

    Question 91 of 97

    1

    The number of oxygen molecules carried by one Hb molecule:

    Select one of the following:

    • 1

    • 2

    • 4

    • 8

    • 3

    Question 92 of 97

    1

    Majority of clotting factors are produced in:

    Select one of the following:

    • liver

    • kidney

    • heart

    • brain

    • muscle

    Question 93 of 97

    1

    Cellular immunity is due to:

    Select one of the following:

    • B lymphocytes

    • T lymphocytes

    • neutrophils

    • eosinophils

    • erythrocytes

    Question 94 of 97

    1

    Action of plasmin is:

    Select one of the following:

    • to remove calcium

    • antithrombin action

    • to stimulate heparin

    • to degenerate fibrin

    • to produce plug

    Question 95 of 97

    1

    Which is the most rare blood group:

    Select one of the following:

    • A Rh+

    • AB Rh+

    • AB Rh-

    • B Rh-

    • O Rh+

    Question 96 of 97

    1

    Hematocrit of 45% means that in the sample of blood analysed:

    Select one of the following:

    • 45% Hb is in the plasma

    • 45% of total blood volume is made up of plasma

    • 45% of Hb is in the RBC

    • 45% of the total blood volume is made up of RBC's and WBC's

    • 45% of blood volume is made of Tr

    Question 97 of 97

    1

    Which of the following statements concerning the monocyte is incorrect:

    Select one of the following:

    • more common in blood than eosinophils and basophils

    • produced in the adult by the bone marrow and lymph nodes

    • unlike neutrophil does not accumulate outside circulation in area of inflammation

    • not classified as a granulocyte

    • 28% of differential blood count