Cholesterol Synthesis

What enzyme is used to make mevalonate from acetoacetyl CoA and acetyl CoA?

What is the committed, rate determining step in cholesterol synthesis?

What electron carrier molecule is required in the first step of cholesterol synthesis?

What are the four ways in which the first step of cholesterol synthesis can be regulated?

What is the transcription factor that binds to HMG CoA Reductase if cholesterol levels are low?

If there is low cholesterol does mRNA translation increase or decrease?

True or false: if there is lots of cholesterol in the body then there is less proteolysis of HMG CoA Reductase (breakdown)?

What causes the enzyme HMG CoA Reductase to become inactivated?

Why is it that high AMP levels cause less phosphorylation of the enzyme HMG CoA reductase?

What kind of reaction is the first step in cholesterol synthesis? What indicates this?

What kind of reaction is the second reaction in cholesterol synthesis? How many ATP are used and how many times does it occur?

What is the final step in cholesterol synthesis (that we need to know)? What is the product?