Christina Wilson
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Anemia lecture; Sickle Cell Anemia lecture

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Christina Wilson
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Anemia

Question 1 of 22

1

How long is the complete maturation process for a RBC?

Select one of the following:

  • 120 days

  • 16-20 days

  • 7 days

  • 90 days

Explanation

Question 2 of 22

1

Erythropoeitin (EPO) initiates and stimulates production of RBCs

Select one of the following:

  • True
  • False

Explanation

Question 3 of 22

1

Which lab test shows the actual volume of RBCs in a unit of whole blood

Select one of the following:

  • Hct

  • Hgb

  • RBC count

  • MCV

Explanation

Question 4 of 22

1

Which lab test is useful in distinguishing between microcytosis anemia and hypochromia anemia?

Select one of the following:

  • MCV

  • MCH

  • Reticulocyte count

  • MCHC

Explanation

Question 5 of 22

1

Select from the dropdown lists to complete the text.

When classifying anemia, first you look at the ( MCH, MCV ) test. If the result is high, then you have a ( macrocytic, normocytic, microcytic ) anemia and need to look at the ( Reticulocyte count, Vitamin B12 and folate levels, Serum ferritin levels ) to determine if the anemia is ( Vitamin B12 deficiency, Anemia of Chronic Disease ) or ( Folic acid deficiency, Iron-deficiency anemia ).

Explanation

Question 6 of 22

1

Microcytic anemias are caused by impaired Hct synthesis.

Select one of the following:

  • True
  • False

Explanation

Question 7 of 22

1

TIBC is decreased in iron deficiency.

Select one of the following:

  • True
  • False

Explanation

Question 8 of 22

1

Which lab test is the best indicator of iron deficiency or iron overload?

Select one of the following:

  • TIBC

  • Serum iron level

  • Ferritin

  • % Transferrin Saturation

Explanation

Question 9 of 22

1

Iron is best absorbed on an empty stomach.

Select one of the following:

  • True
  • False

Explanation

Question 10 of 22

1

Body does not store much vitamin B12 so it is easy and quick to become vitamin B12 deficient.

Select one of the following:

  • True
  • False

Explanation

Question 11 of 22

1

Which of the following lab values are low in vitamin B12 deficiency?

Select one or more of the following:

  • MCV

  • Vitamin B12

  • Reticulocyte count

  • Hct

Explanation

Question 12 of 22

1

What types of foods have high folate levels?

Select one of the following:

  • Meats

  • Fresh green leafy vegetables

  • Cooked green leafy vegetables

Explanation

Question 13 of 22

1

Which anemia includes neurological manifestations?

Select one of the following:

  • Folate deficiency

  • Vitamin B12 deficiency

  • Iron-deficiency

  • Anemia of Chronic Disease

Explanation

Question 14 of 22

1

How long are patients given folate for treatment of Folic Acid deficiency anemia?

Select one of the following:

  • 1 week

  • 2 months

  • 4 months

  • 1 year

Explanation

Question 15 of 22

1

Which of the following is a hemoglobin variant that causes manifestations of sickle cell disease when paired with HbS but does not when paired with itself?

Select one of the following:

  • HbA

  • HbC

  • HbS

  • HbF

Explanation

Question 16 of 22

1

At what age are people screened for sickle cell anemia

Select one of the following:

  • Before 18 years old

  • Before 4 years old

  • Before 2 years old

  • Before 2 months old

Explanation

Question 17 of 22

1

How does hydroxyurea work?

Select one of the following:

  • Destroys HbS

  • Stimulates production of HbF. HbF decreases polymer formation of HbS due to its high oxygen affinity

  • Stimulates production of HbF. HbF decreases polymer formation of HbS due to its low oxygen affinity.

  • Increases levels of HbA so there is a lower percentage of HbS in circulation

Explanation

Question 18 of 22

1

What should always be given with hydroyurea?

Select one or more of the following:

  • Vitamin B12

  • Folic acid

  • Iron

  • Normal RBCs

Explanation

Question 19 of 22

1

AJ is s 25 yo African American female who has sickle cell anemia and has had 2 severe pain crises in the past year. She is a good candidate for hydroxyurea.

Select one of the following:

  • True
  • False

Explanation

Question 20 of 22

1

If toxicity from hydroxyurea occurs, hydroxyurea should be D/C forever.

Select one of the following:

  • True
  • False

Explanation

Question 21 of 22

1

What is the only therapy that can cure sickle cell disease and should it be used for everyone?

Select one of the following:

  • Hydroxyurea; yes

  • Hydroxyurea; no

  • HSCT; yes

  • HSCT; no

Explanation

Question 22 of 22

1

Which of the following sickle cell complications result in an acute decrease in Hgb with decreased reticulocyte count and transient suppression of RBC production in response to bacterial or viral infection?

Select one of the following:

  • Aplastic crisis

  • Acute splenic sequestration crisis

  • Vasooclusive pain crisis

  • Acute chest syndrome

Explanation

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