undergrad Immunology Flashcards on MHC molecules, created by tanitia.dooley on 22/05/2013.
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Created by tanitia.dooley
almost 11 years ago
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Created by tanitia.dooley
almost 11 years ago
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What blocks MHC class II presentation?
Describe the difference between immature and mature dendritic cells
What cytokine is responsible for the conversion into mature dendritic cell?
What do MHC class I recognise?
What cells are MHC class I expressed on?
Describe the structure of the proteosome
How does the proteosome degrade antigens into peptides?
In the MHC class I pathway, how do peptides get from the cytosol into the ER?
How does MHC class I bind the peptide?
Where is the peptide binding groove on MHC class I?
IN MHC class I processing how many AA do proteosomes generate/ TAP recognise/ MHC bind?
Where are peptides trimmed down in the MHC class I pathway?
What is the source of protein for MHC class I?
What is cross presentation?
How does a proteosome change into an immunoproteosome?
where do antigens come from in the MHC class II pathway?
Describe the MHC class II processing pathway of antigens into peptides?
Name two lysosomal/endosomal proteases involved in MHC class II processing?
What is MHC class II complexed with in the ER and what is it role?
What is the role of HLA-DM? Describe its structure
Describe CD4 molecules, MHC class II, helper T cells and TCR interactions
What is the MHC class II genes encoded by?
Describe the difference between TH1 and TH2 cells?
