PHSI3012 09-1 Atherothrombosis

Quiz by Michael Jardine, created more than 1 year ago

PHSI3012 09-1 Atherothrombosis (T2L7) Outline: - Atherothrombosis and its clinical manifestations - Platelet biology and blood clot development - Antithrombotic strategies to combat atherothrombosis

	Created by Michael Jardine over 6 years ago

PHSI3012 09-1 Atherothrombosis (T2L7) Outline: - Atherothrombosis and its clinical manifestations - Platelet biology and blood clot development - Antithrombotic strategies to combat atherothrombosis

PHSI3012 09-1 Atherothrombosis

Question 1 of 19

What’s the most common type of heart disease, and leading cause of death?

Select one of the following:

Explanation

Question 2 of 19

There are two major categories of stroke. 80% are which one?

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Explanation

Question 3 of 19

Platelets are disc-shaped fragments produced by __________.

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Explanation

Question 4 of 19

Average platelet count is:

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Explanation

Question 5 of 19

Which of the following are functional responses of platelets?

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Explanation

Question 6 of 19

Shape change is a crucial functional response of platelets to …something. They change shape from ❌ to ❌

Drag and drop to complete the text.

Explanation

Question 7 of 19

Click on each orange point and select the correct answer.

Which receptor/ligand interactions occur during which bit?

Explanation

Question 8 of 19

Select from the dropdown list to complete the text.

Explanation

Question 9 of 19

Platelet-mediated fibrin clot retraction shrinks the size of the blood clot. Thought to be important for stabilising the clot against shear forces of blood flow. This requires:

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Explanation

Question 10 of 19

Select from the dropdown lists to complete the text.

Explanation

Question 11 of 19

Does Aspirin prevent initial platelet adhesion?

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Explanation

Question 12 of 19

Does Aspirin prolong skin bleeding time?

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Explanation

Question 13 of 19

What’s the efficacy of Aspirin?

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Explanation

Question 14 of 19

Does Aspirin inhibit prostacyclin synthesis?

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Explanation

Question 15 of 19

Does Aspirin stimulate prostacyclin synthesis?

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Explanation

Question 16 of 19

Does Aspirin suppress the release of thrombogenic factors from platelets?

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Explanation

Question 17 of 19

Integrin αIibβ3 (GPIIbIIIa) inhibitors are:

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Explanation

Question 18 of 19

Which of the following are CURRENT (not further potential) antithrombotic treatments:

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Explanation

Question 19 of 19

PAR antagonists are under development as a potential novel antithrombotic. What’s PAR?

Select one of the following:

Explanation