Mak Sch
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Biologie Quiz on Neurodeg5HD, created by Mak Sch on 01/12/2017.

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Mak Sch
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Neurodeg5HD

Question 1 of 11

1

Main clinical cognitive features of Huntington’s disease include the following except:

Select one of the following:

  • B. Memory difficulties

  • A. Mental slowing

  • C. Language severe problems

  • D. Language well preserved

Explanation

Question 2 of 11

1

Question 2
Characteristics in Early stages of Huntington’s disease:
(multiple answers possible)

Select one or more of the following:

  • A. Chorea

  • B. Agitated /mood swings

  • C. Distractable

  • D. Demented

Explanation

Question 3 of 11

1

Characteristics in Late stages of Huntington’s disease except: (multiple answers possible)

Select one of the following:

  • B. Dystonia/bradykinetic

  • C. Mood swings

  • D. Demented

  • A. Abulic

Explanation

Question 4 of 11

1

Question 7
The gene related to Huntington’s disease is Huntingtin (htt) and in order to become pathogenic it should have:

Select one of the following:

  • B. >36 insertions

  • C. >36 deletions

  • D. >36 GAC repeats

  • A. >36 CAG repeats

Explanation

Question 5 of 11

1

Main clinical psychiatric features of Huntington’s disease include:
(multiple answers possible)

Select one or more of the following:

  • A. Irritability

  • B. Stable mood

  • D. Compulsive behaviour

  • C. Social withdrawal

Explanation

Question 6 of 11

1

The brain structures which are mainly affected by Huntington’s disease are:
(multiple answers possible)

Select one or more of the following:

  • A. Sustantia Nigra

  • B. Cerebral cortex

  • C. Hippocampus

  • D. Striatum

Explanation

Question 7 of 11

1

Main clinical motor features of Huntington’s disease include:
(multiple answers possible)

Select one or more of the following:

  • A. Chorea

  • B. Evolution from hyperkinetic to hypokinetic

  • C. Evolution from hypokinetic to hyperkinetic

  • D. Gait abnormalities

Explanation

Question 8 of 11

1

Question 8
Other features frequently found in patients with Huntington’s disease are the following except:



Select one of the following:

  • A. Metabolic abnormalities

  • B. Weight gain

  • C. Circadian rhythm disturbances

  • D. Autonomic abnormalities

Explanation

Question 9 of 11

1

Question 9
Huntington’s disease is an inherited disorder, it is a _____ condition.

Select one of the following:

  • Aut Dom

  • Aut Rec

  • X Dom

  • X Rec

Explanation

Question 10 of 11

1

Question 10
Mutated Huntingtin lead to:
(multiple answers possible)

Select one or more of the following:

  • A. Transcription interference

  • B. Formation of inclusions

  • C. Cellular dysfunction

  • D. Cell death

Explanation

Question 11 of 11

1

The gene defect Huntington’s disease is known to be on Chromosome

Select one of the following:

  • 2

  • 4

  • 9

  • 11

Explanation

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