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How much of the total ECF does plasma make up? What are the two major components of blood?
What are the components of plasma?
How much do each of the three classes of protein contribute to the total amount of protein in the plasma? What is the function of each?
What are the different plasma ions? What are their functions? (2)
What is the carbonic buffer equation in the blood? What is the point of this? How does haemoglobin bind hydrogen?
How are nutrients vs. waste products carried in the plasma? What else is carried in the plasma?
Describe the hematopoiesis cascade
What is the function of erythrocytes? What do they contain/not contain? Average lifespan? How many are made per hour? What (mainly) controls RBC production? What does this mean in terms of pathology?
Describe the structure of haemoglobin. What happens when O2 binds? What is the Bohr effect and what triggers it?
How many people does anaemia affect worldwide? What are the haemoglobin levels associated with men in anaemia? Women?
What is anaemia? What is the bodies response to anaemia?
What are the symptoms of anaemia?
What are the signs of anaemia?
What are the three different classes of anaemia?
What are the underlying causes of microcytic anaemia?
What causes normocytic anaemia?
What can cause macrocytic anaemia?
What are the common underlying causes of iron deficiency anaemia (microcytic cells, hypochromic)?
How big are platelets? What is there lifespan? How many are produced every second?
What are the two components which contribute to the formation of a thrombus? What happens as a result of too low levels of either of these?
Which is the most common WBC? Describe its structure. What is its half life? How many are produced per second? What is its function?
When is there an increase in the concentration of neutrophils? What causes a deficiency (neutropenia)?
What is this? Describe its features. When does its concentration increase?
What is this? Describe its characteristics.
What is this? Describe its characteristics. What is its primary function? When does it increase?
What is this? Describe its characteristics. What can it become (and what are the function of those cells). When do these increase? Lifespance?
What can bone marrow failure lead to? What can cause bone marrow failure? What tends to actually kill people with bone marrow failure?
What are the different counts which can be done to detect haematological disorders?
What is used to prepare a blood film? What is the purpose of a blood film? What is the final blood test which could be used?
