Idiopathic Osteosclerosis
(Enostosis, dense bone island)

Reported prevelance of idiopathic osteosclerosis

Condensing/sclerosing osteitis

Cherubism

Hypophosphatasia

Odontophosphatasia

Clinical features of hypophosphatasia

Paired incisive canals open into a single incisive foramen & transmit...

Nasopalatine duct cyst arieses from...

Nasaopalatine duct cyst differential diagnosis

Nasopalatine duct cyst management

Cyst of the incisive papilla

Surgical ciliated cyst

Epidemiology of Simple bone cysts

Gnathic Simple Bone Cyst

Differential diagnosis of Gnathic simple bone cyst

Central Giant Cell Granuloma (CGCG)

Aggressive CGCGs characterized by...

Management & Prognosis of CGCG

Recurrent CGCG lesions

Epidemiology of Aneurysmal Bone Cyst (ABC)

ABC clinical differential diagnosis

Management & Prognosis

Hematopoietic bone marrow defect

Myospherulosis

Cause of Myospherulosis

Presentation

Treatment

Osteonecrosis (avascular necrosis)

Medication related osteonecrosis of teh jaws (MRONJ)

What are bisphosphonates?

When are bisphosphonates administered?

IV bisphosphonates every 3-4 weeks for bone metastases
(zoledronate/zometa; pamidronate/aredia)

IV bisphosphonates once yearly for osteoporosis
(zoledronate/reclast)

Oral bisphosphonates taken daily/weekly/monthly for osteoporosis
(alendronate/fosamax; risedronate/actonel; ibandronate/bonvia)

What is denosumab?

When is denosumab administered?

Subcutaneous administration of denosumab every 6months for osteoporosis
(Prolia)

Subcutaneous administration of denosumab every 4 weeks for bone metastases
(Xgeva)

MRONJ Risk Factors: site

MRONJ Risk Factors: Duration of dose

MRONJ Risk Factors: Age

MRONJ: Other risk factors

Diagnosis of MRONJ

Stage 0 MRONJ

S

Stage 2 MRONJ

Stage 3 MRONJ

Treatment of MRONJ

MRONJ & dental considerations

Osteoradionecrosis

Osteoradionecrosis of the jaws

Majority of Osteoradionecrosis of the Jaws occur...

Management of Osteoradionecrosis of the jaws

Prevention represents best course of action (Osteoradionecrosis)

Spontaneous sequestration (osteonecrosis)

Other causes of osteonecrosis

Fibrous dysplasia

Fibrous dysplasia manifestation

Fibrous dysplasia variable phenotypic expressions
Monostotic FD (85-90%)

Fibrous dysplasia variable phenotypic expressions
Polyostotic FD (10-15%)

Fibrous dysplasia variable phenotypic expressions
McCune-Albright Syndrome (<5%)

Extent of disease (FD) correlates w

Radiographic appearance of FD

Craniofacial fibrous dysplasia

Fibrous dysplasia Diagnosis & Management

Cemento-ossifying fibroma

Cemento-ossifying fibroma Radiographic appearance

Aggressive (juvenile) ossifying fibromas
-Trabecular ossifying fibroma

Aggressive (juvenile) ossifying fibromas
-Psammomatoid ossifying fibroma

Gigantiform cementoma

Cemento-osseous dysplasia

Cemento-osseous dysplasia

Takes months/years to develop & radiographic appearance depends on maturity of lesion

Cemento-osseous dysplasia most frequently occurs in...

Periapical COD

Focal COD

Multifocal COD

Florid COD

Management of COD

Osteoma

Osteoma Diagnosis

Bones/areas affected by Osteoma

Osteoid osteoma & osteoblastoma

Osteoid Osteoma

Osteoblastoma

Osteosarcoma

Osteosarcoma survival

Osteosarcoma of Gnathic bones

What percent of mandibular and maxillary osteosarcomas recur

Radiographic appearance of Gnathic Osteosarcoma

Osteosarcoma, Codman triangle, & 'sunburst' appearance

Surface osteosarcomas

Periosteal osteosarcoma

Parosteal osteosarcoma

Chondrosarcoma

Chondrosarcoma statistics

Chondrosarcoma Precursor lesions

Low/intermediate grade Chondrosarcoma

High-grade chondrosarcoma

Mesenchymal chondrosarcoma

Metastases to gnathic bones

Radiographic appearance of metastatic disease

Synovial Chondromatosis

Synoviuim

Treatment of Synovial chondromatosis

Synovial Chondromatosis characteristics