Matthew Coulson
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Anxiety lecture given on Monday + Pharmacology of Anxiolytic Drugs given on Friday - both of week 2

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Matthew Coulson
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Anxiety & The Pharmacology of Anxiolytic Drugs (2 lectures)

Question 1 of 26

1

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The ( Amygdala, Central Nucleus, Mammillary Body, Putamen, Lenticular Nucleus ) acts as the emotional filter of the brain. Located in the medial temporal lobe, it helps to decide whether a stimulus requires a stress or fear response.

Explanation

Question 2 of 26

1

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Generalised anxiety tends to only be diagnosed when symptoms have been going on most days for at least ( 6 months, 3 months, 1 year )

Explanation

Question 3 of 26

1

Females are more likely than males to develop generalised anxiety disorder

Select one of the following:

  • True
  • False

Explanation

Question 4 of 26

1

SSRIs can be used in the treatment of generalised anxiety disorder

Select one of the following:

  • True
  • False

Explanation

Question 5 of 26

1

Which Gabapentinoid is typically used in the treatment of generalised anxiety disorder?

Select one of the following:

  • Pregabalin

  • Gabapentin

  • Citalopram

  • Fluvoxamine

Explanation

Question 6 of 26

1

Which 3 of the following are known common symptoms of anxiety?

Select one or more of the following:

  • Palpitations

  • Chest pain

  • Depersonalisation

  • Visual disturbance

  • Hallucinations

  • Cough

Explanation

Question 7 of 26

1

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disorder is defined as recurrent attacks of severe anxiety which are not restricted to any particular situation or set of circumstances and are therefore unpredictable

Explanation

Question 8 of 26

1

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Over 50% of patients with panic disorder have ( Agoraphobia, Acrophobia, Atychiphobia, Aphenphosmphobia, Anthropophobia ), a type of anxiety in which you fear and avoid places or situations that might cause you to panic and make you feel trapped

Explanation

Question 9 of 26

1

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It has been discussed that one of the potential causes for sporadic panic attacks is the buildup of acid in acid-sensitive fear pathways.

Explanation

Question 10 of 26

1

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Which benzodiazepine, listed in the World Health Organization’s Essential Drug List, can be used to treat anxiety disorders such as GAD and Panic Disorder?

Explanation

Question 11 of 26

1

A persistent fear of one or more social or performance situations in which the person is exposed to unfamiliar people or to possible scrutiny by others is known as ...

Select one of the following:

  • Social Anxiety Disorder

  • Social Depressive Disorder

  • Crowd Paralysis Disorder

  • Crowd Anxiety Disorder

  • Social Paralysis Disorder

Explanation

Question 12 of 26

1

Treatment of Social Anxiety Disorder tends to be treated, in the initial stages, via which of the following therapies?

Select one of the following:

  • Cognitive Behavioural Therapy

  • SSRIs/SNRIs

  • Benzodiazepines (such as Diazepam)

Explanation

Question 13 of 26

1

Fill the blank space to complete the text.

A patient 17 year old boy presents to his GP complaining of an incessant need to to tidy his room, so much so that his things are completely perfectly arranged. This has been going on for around 2 months now. He describes this obsessive cleaning as unenjoyable and claims he only does it to 'neutralise' his irresistible urges.
What condition is this person likely suffering from?
Disorder

Explanation

Question 14 of 26

1

OCD incidence:
Peak incidence in males is between
Peak incidence for females is between

Drag and drop to complete the text.

    13-15
    24-25
    44-47

Explanation

Question 15 of 26

1

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60-90% of patients with OCD will experience at least 1 major ( depressive, manic ) episode

Explanation

Question 16 of 26

1

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The most common therapy for Obsessive Compulsive Disorder is ( Cognitive Behavioural Therapy, SSRIs, Benzodiazepines (e.g. Diazepam) )

Explanation

Question 17 of 26

1

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Benzodiazepines act as agonists of a ( GABA, Glutamate, Dopamine, Noradrenaline ) receptor, thus promoting relaxation and anticonvulsant effects.

Explanation

Question 18 of 26

1

Combining Benzodiazepines with Alcohol is not recommended, however does not generally cause any negative effects.

Select one of the following:

  • True
  • False

Explanation

Question 19 of 26

1

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The GABA receptors are ( ionotropic, metabotropic ) receptors on ( chloride, potassium, sodium ) channels

Explanation

Question 20 of 26

1

Which of the following benzodiazepines is the mainstay of the alcohol withdrawal program at ninewells?

Select one of the following:

  • Diazepam

  • Lorazepam

  • Chlordiazepoxide

  • Clorazepate

  • Temazepam

Explanation

Question 21 of 26

1

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Benzodiazepines + alcohol typically leads to ( respiratory depression, heart failure, syncope, cerebral ischaemia )

Explanation

Question 22 of 26

1

Benzodiazepines should not be immediately withdrawn. They should instead be phased out to allow the body to restore its natural mechanisms of producing and reacting to GABA.

Select one of the following:

  • True
  • False

Explanation

Question 23 of 26

1

Immediate withdrawal of benzodiazepines from a patient's treatment plan could cause which 2 of the following symptoms?

Select one or more of the following:

  • Anxiety

  • Convulsions

  • Depression

  • GI Upset

  • Respiratory Depression

Explanation

Question 24 of 26

1

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( Serotonin, Noradrenaline, Dopamine ) is the key neurotransmitter in the Amygdala

Explanation

Question 25 of 26

1

In a patient with Generalised Anxiety Disorder who has not responded positively to CBT, what should be the first line pharmacological treatment?

Select one of the following:

  • Sertraline

  • Fluoxetine

  • Duloxetine

  • Mirtazapine

  • Pregabalin

  • Gabapentin

Explanation

Question 26 of 26

1

In a patient in which SSRIs have not worked or are contraindicated, what is the next step in the drug treatment of a generalised anxiety patient?

Select one of the following:

  • Mirtazapine

  • Duloxetine

  • Carbamazepine

  • Amitriptyline

  • Pregabalin

Explanation

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