Basal Ganglia

Question 1 of 20

1

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Basal Ganglia:

STR:
GP:
STN:
SNr:

Explanation

Question 2 of 20

1

Basal ganglia

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Caudate nucleus

Putamen

Globus pallidus

Subthalamic nucleus

Substantia nigra

Caudate nucleus (sideways)

Putamen (sideways)

Explanation

Question 3 of 20

1

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Box and arrow model

Explanation

Question 4 of 20

1

Pathways

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Hyperdirect pathway

Direct pathway

Indirect pathway

Explanation

Question 5 of 20

1

Function:

Hyperdirect pathway: ❌
Direct pathway: ❌
Indirect pathway: ❌

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STOP (-)

GO (+)

NO-GO (-)

Explanation

Question 6 of 20

1

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The ( striatum, subthalamic nucleus, substantia nigra, globus pallidus ) is the main input region for the basal ganglia.

Explanation

Question 7 of 20

1

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Dorsal striatum: ( Caudate nucleus, subthalamic nucleus, substantia nigra pars reticulata ) + ( putamen, globus pallidus internal, substantia nigra pars compacta )
Ventral striatum: ( Nucleus accumbens, Caudate nucleus, Subthalamic nucleus ) + ( olfactory tubercle, putamen, globus pallidus external )

Explanation

Question 8 of 20

1

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Medium spiny neurons with D1 and D2 receptors can be found in the ( striatum, globus pallidus, subthalamic nucleus, substantia nigra ).

D1 neurons project to the ( direct, indirect, hyperdirect ) pathway.
D2 neurons project to the ( indirect, direct, hyperdirect ) pathway

Explanation

Question 9 of 20

1

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Medium spiny neurons in the striatum show a preference for the ( contralateral, ipsilateral ) side.

Explanation

Question 10 of 20

1

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In the classical model the globus pallidus is believed to be the ( relay, amplifier, supplier of feedback inhibition ) of the striatum.

Explanation

Question 11 of 20

1

Globus pallidus internal: ❌
Globus pallidus external: ❌

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medial

lateral

Explanation

Question 12 of 20

1

The subthalamic nucleus is part of the

Select one of the following:

indirect and the hyperdirect pathway
the direct pathway
the indirect pathway

Explanation

Question 13 of 20

1

The subthalamic nucleus

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has a motor part, an associative part and a limbic part.
is only involved in motor control.
is only involved in association.
is involved in association and the limbic system.

Explanation

Question 14 of 20

1

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The ( substantia nigra pars reticulata, substantia nigra pars compacta, subthalamic nucleus ) and the ( globus pallidus internal, globus pallidus external, striatum ) are the main output structures of the basal ganglia.

Output typically consists of ( GABAergic, dopaminergic ) projections to the ( thalamus, cerebellum, brain stem ).

Explanation

Question 15 of 20

1

Substantia nigra pars compacta:
- ❌
- ❌ergic

Substantia nigra pars reticulata:
- ❌
- ❌ergic

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Input

Output

dopamin

GABA

Explanation

Question 16 of 20

1

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The term "convergence of information" means that there are ( less, more ) neurons in regions further down the processing pathway.

Explanation

Question 17 of 20

1

Which one is true?

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Only humans and higher primates have basal ganglia.
All vertebrates have basal ganglia.

Explanation

Question 18 of 20

1

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Movement initiation:

There is a sharp ( increase, decrease ) in the firing rate of medium spiny neurons in the ( striatum, globus pallidus, subthalamic nucleus ).
This leads to a sharp ( decrease, increase ) in the firing of output neurons in the ( substantia nigra pars reticulata, substantia nigra pars compacta, subthalamic nucleus ).
This in turn releases inhibition in target neurons, e.g. the ( superior colliculus, thalamus, globus pallidus ) for eye movement.

Explanation

Question 19 of 20

1

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Parkinson's disease is characterized by the loss of ( dopaminergic, GABAergic ) neurons in the ( substantia nigra pars compacta, substantia nigra pars reticulata, striatum ).

This leads to a lack of ( excitation, inhibition ) of the direct pathway and a lack of ( inhibition, excitation ) on the indirect pathway, which results in ( slow, fast ) movements.
Another result is ( hyperactivity, hypoactivity ) in the subthalamic nucleus.

	Created by Lukas Paulun over 5 years ago

Master Neuroscience (From Membrane to Brain [Lecture]) Quiz on Basal Ganglia, created by Lukas Paulun on 30/11/2018.

Basal Ganglia

Question 1 of 20

Fill the blank spaces to complete the text.

Basal Ganglia: STR: GP: STN: SNr:

Explanation

Question 2 of 20

Basal ganglia

Drag an answer into the correct orange point.

Explanation

Question 3 of 20

Click on each orange point and write the correct answer.

Box and arrow model

Explanation

Question 4 of 20

Pathways

Drag an answer into the correct orange point.

Explanation

Question 5 of 20

Function: Hyperdirect pathway: ❌ Direct pathway: ❌ Indirect pathway: ❌

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Explanation

Question 6 of 20

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The striatum subthalamic nucleus substantia nigra globus pallidus( striatum, subthalamic nucleus, substantia nigra, globus pallidus ) is the main input region for the basal ganglia.

Explanation

Question 7 of 20

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Explanation

Question 8 of 20

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Explanation

Question 9 of 20

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Medium spiny neurons in the striatum show a preference for the contralateral ipsilateral( contralateral, ipsilateral ) side.

Explanation

Question 10 of 20

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In the classical model the globus pallidus is believed to be the relay amplifier supplier of feedback inhibition( relay, amplifier, supplier of feedback inhibition ) of the striatum.

Explanation

Question 11 of 20

Globus pallidus internal: ❌ Globus pallidus external: ❌

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Explanation

Question 12 of 20

The subthalamic nucleus is part of the

Select one of the following:

Explanation

Question 13 of 20

The subthalamic nucleus

Select one of the following:

Explanation

Question 14 of 20

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Explanation

Question 15 of 20

Substantia nigra pars compacta: - ❌ - ❌ergic Substantia nigra pars reticulata: - ❌ - ❌ergic

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Explanation

Question 16 of 20

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The term "convergence of information" means that there are less more( less, more ) neurons in regions further down the processing pathway.

Explanation

Question 17 of 20

Which one is true?

Select one of the following:

Explanation

Question 18 of 20

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Explanation

Question 19 of 20

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Explanation

Question 20 of 20

Fill the blank space to complete the text.

The is the only basal ganglia region with glutamatergic projections.

Explanation

Basal Ganglia:

STR:
GP:
STN:
SNr:

Function:

Hyperdirect pathway: ❌
Direct pathway: ❌
Indirect pathway: ❌

The ( striatum, subthalamic nucleus, substantia nigra, globus pallidus ) is the main input region for the basal ganglia.

Medium spiny neurons in the striatum show a preference for the ( contralateral, ipsilateral ) side.

In the classical model the globus pallidus is believed to be the ( relay, amplifier, supplier of feedback inhibition ) of the striatum.

Globus pallidus internal: ❌
Globus pallidus external: ❌

Substantia nigra pars compacta:
- ❌
- ❌ergic

Substantia nigra pars reticulata:
- ❌
- ❌ergic

The term "convergence of information" means that there are ( less, more ) neurons in regions further down the processing pathway.