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What are the 7 steps in the modern drug discovery process?
Name 3 methods for identifying drug targets
What are isosteres?
Name 2 tests that are used to detect genotoxicity of a new drug
What is meant by lead discovery in drug discovery process?
What is the Easson-Stedman Hypothesis?
What is combinatorial synthesis?
Name 4 drug related factors that affect the transport of drugs across biological membranes
According to Lipinkski's rule of five, what 4 factors affect drug absorption?
What is the most commonly encountered reason for using pro-drugs for the delivery of therapeutic agents?
What does QSAR stand for?
What is a prodrug?
Name 4 types of drug degradation
What 5 factors will the particle size of a drug affect?
What are the 3 basic rules of formulation design?
What 3 factors determine if a drug should be formulated as a SVP or a LVP?
What are the 8 components of a Target Product Profile?
What is Pharmacoeconomics?
What two properties do class 2 drugs in the biopharmaceutical classification system have?
What characteristics of a drug has the greatest effect on the rate of passage through a biological membrane via passive diffusion?
What is the role of propylene glycol in a transdermal formulation?
A drug molecule has high aqueous solubility and low permeability. What class in the biopharmaceutical classification system would it belong to?
What is a pharmacophore?
What is the most commonly used measurement of lipophilicity?
What is the most common type of drug target?
