Stabilisation:

Cap, PolyA tail and PolyA binding proteins promote stabilisation
PolyA proteins bind to other proteins that bind to Cap= circulisation of mRNA which protects ends being chewed by enzymes
Leave nucleus into cytoplasm which needs stabilised mRNA

Involvement in export:

mRNA needs to be transported to cytoplasm to be translated
Proteins that do shuttling of RNAs out of nucleus recognise cap and polyA/(PABPs)

Involvement in translation:

Translation is initiated through cap binding proteins that recognise cap

	Created by Chloe Cavarretta over 7 years ago

MBBB L13