Physiological Homeostasis

1

What is the idea of hierarchy of importance in terms of homeostasis?

1

An example of the hierarchy of importance in homeostasis is a high salt intake. This increases of the blood. Thus, more moves into the blood. This balances osmolarity but increases . Thus, MABP increases which causes in the long term. Whilst hypertension is undesirable for the body, the more immediate high osmolarity in the blood caused by excessive salt intake must be dealt with in this way.

1

What is the correct name of the mechanism in which:
A variable is regulated about set point
A change in that variable is compared against that point
Deviation from that point leads to a response
The response moves the variable back to the set point
And turns the response off

1

❌ - detect changes in the physiological variable
❌ - carries signals from sensors to integrating centre
❌ - compares inputs from sensors against physiological set point and elicits a response
❌ - carries signals from integrating centre to effectors
❌ - produces a response to bring the physiological variable back to the set point

Sensors

Afferent pathway

Integrating centre

Efferent pathway

Effector

Receptors

Medulla oblongata

Efferent path

Integrating centres

Organising centre

Central nervous system

Afferent path

Efferent nerves

Responder

Peripheral nervous system

1

Which of these structures are examples of neuronal integrating centres in the brain?

1

In homeostatic negative feedback mechanisms, what must there be to allow fine-tuning of variables?

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This diagram shows the two systems involved in thermoregulation. Label it.

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This diagram shows the endocrine systems in the body. Label it.

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All hypothalamic/pituitary hormones are peptides, polypeptides or glycoproteins

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This diagram shows the endocrine hormone negative feedback arc controlling blood glucose. Label it.

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What is a local homeostatic control mechanism?

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One example of a local negative feedback mechanism is in skeletal muscle. When skeletal muscle is contracting at a fast rate, there is increased and concentration in the blood. This is sensed in the which stimulates them to . This increases blood flow to the muscles. This removes and from the tissue and thus their concentrations return to normal.

1

What is the correct name of the mechanism in which:
A change in a variable is anticipated
A response to that change is brought about before that change is even actually detected

1

The fight or flight response is an example of a feed-forward control mechanism.
When a threat is perceived, the nervous system anticipates physical exertion whereby the individual will need to fight the threat or flee from it.
The sympathetic nervous system activates the release of noradrenaline and to increase heart and blood flow in the . This prepares the body for increased demand.

1

Feed-forward mechanisms can be the result of learned behaviour. For example...
'Cues' can be associated with an incoming meal. Therefore, this cue will trigger anticipation of .
The nervous system stimulates the secretion of and .
This prepares the body for digestion before food is even ingested.

1

What is the correct name of the mechanism in which:
A change in a variable triggers a response
That response furthers the change in that variable
The variable is therefore amplified, not normalised

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One example of a positive feedback mechanism is parturition.
When the head of the foetus begins to push against the cervix, are transmitted to the brain. The gland is stimulated to secrete . This is carried in the to the uterus. It then stimulates uterine which push the baby towards the cervix. Therefore, the will be stimulated even more so more will be secreted. The mechanism is terminated when the baby is born.

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Hormones are derived from steroids only

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Select all the properties that apply to peptide/protein/glycoprotein hormones.

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Select all the properties that apply to steroid and thyroid hormones

Principles of Physiology and Pharmacology Quiz on Physiological Homeostasis, created by Charlotte Jakes on 24/11/2019.