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Pain and Some Neurological Disorders- Clinical Pharmacology 5th Year PMU

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Pain and Some Neurological Disorders- Clinical Pharmacology 5th Year PMU

Question 1 of 16

1

Opioid analgesics are suitable for treatment of

Select one or more of the following:

  • traumatic shock

  • acute myocardial infarction

  • malignant pain

  • neuropathic pain

Explanation

Question 2 of 16

1

Pethidine is indicated for

Select one or more of the following:

  • strong acute pain as some crisis

  • chronic pain in cancer patients

  • toothache

  • headache

Explanation

Question 3 of 16

1

Point out the correct statement for opioid analgesics

Select one or more of the following:

  • binds to specific opioid receptors

  • cause dependence and abuse

  • in high doses suppress the respiratory center

  • showed withdrawal in long term therapy

Explanation

Question 4 of 16

1

Which are the therapeutic effects of NSAIDs

Select one or more of the following:

  • analgesic

  • antipyretic

  • anti-inflammatory

  • cough suppressants

Explanation

Question 5 of 16

1

The main mechanism of action of NSAIDs is

Select one of the following:

  • inhibition of COX enzymes

  • inhibition of phosphodiesterase

  • bind to dopamine receptors

  • bind to opioid receptors

Explanation

Question 6 of 16

1

Which are the indications for prescribing NSAIDs

Select one or more of the following:

  • arthritis

  • toothache

  • radiculitis

  • neuropathic pain

Explanation

Question 7 of 16

1

Which are ADRs of NSAIDs

Select one or more of the following:

  • ulceration of gastric mucosa

  • asthma

  • agranulocytosis

  • liver damage in high doses

Explanation

Question 8 of 16

1

Which are contraindications for NSAIDs non-selective COX inhibitors

Select one or more of the following:

  • asthma

  • peptic ulcer

  • liver insufficiency

  • kidney insufficiency

Explanation

Question 9 of 16

1

In which cases step-wise pain killing approach is used

Select one of the following:

  • patients with cancer pain

  • patients with crisis

  • patients with toothache

  • patients with headache

Explanation

Question 10 of 16

1

Which are the ADRs of NSAIDs the selective COX-2 inhibitors

Select one or more of the following:

  • cardio-toxicity

  • epidermal necrolysis

  • peptic ulcer

  • depressed fertility

Explanation

Question 11 of 16

1

Typical for mixed type of insomnia are the following features

Select one or more of the following:

  • difficulty to fall asleep

  • easy fall asleep

  • awakening during the night

  • early awaking

Explanation

Question 12 of 16

1

The benzodiazepines and some barbiturates exert the following ADRs

Select one or more of the following:

  • hypertension

  • drug tolerance and dependence

  • slowed reflex time and myorelaxation

  • morning sleepiness for the drugs which form active metabolites

Explanation

Question 13 of 16

1

Triptans are used for treatment of

Select one of the following:

  • acute migraine

  • prevention of migraine

  • cancer pain

  • allergies

Explanation

Question 14 of 16

1

Adverse drug reactions of triptans are

Select one or more of the following:

  • sleepiness

  • fatigue and dizziness

  • hyperglycemia

  • paresthesias

Explanation

Question 15 of 16

1

Which of the following drugs are used to treat headache

Select one or more of the following:

  • Beta-blockers

  • Triptans

  • Opioid analgesics

  • NSAIDs

Explanation

Question 16 of 16

1

The rational drug combinations for treatment of headache are between the following drugs

Select one or more of the following:

  • NSAIDs and spasmolytics

  • NSAIDs and coffein

  • Opioid analgesics and NSAIDs

  • Analgesics and calcium channel antagonists

Explanation

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