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Pharm II-Exam I Quiz II

Pharm II-Exam I Quiz II

Question 1 of 15

1

Which of the following is not an adverse effect of isoniazid

Select one of the following:

  • Hepatitis

  • Loss of appetite

  • N/V

  • Jaundice

  • Orange color to all body secretions

Explanation

Question 2 of 15

1

Which of the following anticancer drugs is an alkylating agent

Select one of the following:

  • Chlorabucil

  • Methotrexate

  • 5-FU

  • Asparaginase

Explanation

Question 3 of 15

1

This anticancer drug is an enzyme preparation isolated for E. Coli that hydrolyzes circulation L-asparagine to aspartic acid and ammonia. AE include include hypersensitivity rxn s/a rash, fever, chills, urticaria and bronchospasm.

Select one of the following:

  • Asparaginase

  • Chlorabucil

  • Methotrexate

  • 5-fluorouracil

Explanation

Question 4 of 15

1

Mindy is a 45 y/o female who comes in to your office due to stinging and burning down below. When asked about her social history she says that she has recently been divorced and been loving the single life and hitting up single events and has had several new sexual adventures. Pt notes that since she is in menopause she hasn't really been using that much protection. On exam you note several tender vesicular lesions on her labia. Which of the following would be your choice for tx of this patient?

Select one of the following:

  • Acyclovir

  • Methotrexate

  • Amoxicillin

  • Penicillin G

Explanation

Question 5 of 15

1

Bob is a 72 y/o male who is brought into your clinic due to confusion. Pt's daughter says he has experienced these sx before when the had a UTI. Urinalysis confirms this diagnosis. Which of the following drugs is contra-indicated to treat this pt.

Select one of the following:

  • Ciprofloxacin

  • Cephalexin

  • Cefazolin

  • Co-trimoxazole

Explanation

Question 6 of 15

1

This drug acts by binding to peptidoglycan strand of cell wall and prevents further growth of the cell wall. It is not absorbed from the GI tract and is excreted unchanged via the kidneys. What is this drug?

Select one of the following:

  • Vancomycin

  • Bacitracin

  • Ampicillin

  • Doxycycline

Explanation

Question 7 of 15

1

Which of the following is NOT a beta lactam?

Select one of the following:

  • Pipericillin

  • Cephalexin

  • Cluvanic acid

  • Polymixins

Explanation

Question 8 of 15

1

Which of the following antiretroviral drugs is not safe during pregnancy?

Select one of the following:

  • Tenofovir

  • Emtricitabine

  • Efaviren

  • Raltegravir

Explanation

Question 9 of 15

1

Which anticancer drug is a/w vitamin A toxicity which can be a/w HA, fever, and dry skin?

Select one of the following:

  • Retinoic Acid

  • Asparaginase

  • Chlorabucil

  • Cyclophosphamide

Explanation

Question 10 of 15

1

Which antifungal is indicated for onychomycoses tinea corporis and tinea cruris

Select one of the following:

  • Terbinafine

  • Grisoulvin

  • Imidazole

  • Itraconazole

Explanation

Question 11 of 15

1

Which antifungal class inhibits the enzyme 14-alpha-demethylase?

Select one of the following:

  • Azole antifungals

  • Echinocandins

  • Fluoroquinolones

  • Nystatin

Explanation

Question 12 of 15

1

This class of antiretroviral drugs act by binding to reverse transcriptase, inhibits DNA polymerase (do not resemble ACTG)?

Select one of the following:

  • Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

  • Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

  • Protease Inhibitors (PIs) (-navir)

  • Integrase Inhibitors

Explanation

Question 13 of 15

1

Which of the following conditions put patients at risk of hemolysis when being treated w/ chloroquine for malaria?

Select one of the following:

  • G6PD

  • Sickle Cell Anemia

  • HTN

  • Lupus

Explanation

Question 14 of 15

1

This group of antibiotics acts by inhibiting bacterial DNA gyrase [DNA gyrase converts closed circular DNA into supercoiled configuration] preventing supercoiling and stops DNA replication

Select one of the following:

  • Fluoroquinolones

  • Sulfonamides

  • Trimethoprim

  • Riframpin

Explanation

Question 15 of 15

1

Red man syndrome, a possible AE effect of vancomycin, is d/t which of the following mechanisms?

Select one of the following:

  • Mast breakdown, leading to histamine release and subcutaneous vasodilation

  • Subcutaneous thrombocytopenia due to abnormal production of clotting factors

  • Psych disorder where patients will paint their skin red and think they are the devil.

  • None of the answers are correct.

Explanation

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