Elisabeth Haasen
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cycle 1 Physiology Quiz on 2020 cycle 1 final corrective, created by Elisabeth Haasen on 10/11/2021.

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Elisabeth Haasen
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2020 cycle 1 final corrective

Question 1 of 29

1

Which of following statements properly describe characteristics of facilitated diffusion?

Select one or more of the following:

  • In facilitated diffusion, membrane carriers enable movement of molecules through the cellular membrane against concentration gradient

  • Particular membrane carrier is able to transfer one particular type of molecules soluble in water

  • Facilitated diffusion characterizes with finite rate of transfer of substance defined as maximum saturation

  • Water molecules pass from the cell of the collecting duct to its lumen through the system of facilitated diffusion called AQP2

Explanation

Question 2 of 29

1

Which of the following statements properly describe agglutination:

Select one or more of the following:

  • Administration of aspirin slows the process of agglutination

  • Agglutination is in vitro phenomenon resulting from an interaction between the agglutinogen and agglutinin

  • Gamma globulins of IgM class easily agglutinate erythrocytes in room temperature

  • Agglutination is slowed by albumin molecules

Explanation

Question 3 of 29

1

3. Which of following statement concerning active transport are true?

Select one or more of the following:

  • Na/K ATP-ase exchanges 2 sodium ions for 1 potassium ion. Each such exchange requires two ATP molecules

  • Co-transportation of glucose and sodium ions requires previous action of Na/K ATP-ase. Such the mechanism is an example of secondary active transport

  • Calcium ions are actively pumped into cellular cytosol by the calcium ATP-ase. This mechanism maintains higher concentration of calcium in cellular cytosol than in ECF

  • Active transport mechanisms are able to move substances against concentration gradient

Explanation

Question 4 of 29

1

4. Which of following statements properly describes beta-adrenergic receptors?

Select one or more of the following:

  • B-adrenergic receptor is a ligand-gated channels

  • Actively of some adrenergic receptors brings EPSP to the postsynaptic membranes

  • Beta-adrenergic receptors initiate transduction resulting with activation of adenylate cyclase

  • Activation of beta-adrenergic receptors up-regulates synthesis of cAMP

Explanation

Question 5 of 29

1

Which of following statements concerning thromboxane A2 (TxA2) are true?

Select one or more of the following:

  • It activates fibrinolysis

  • TxA2 activates platelets- it intensifies their degranulation (release of the content of granules).

  • It prevents aggregation of platelets

  • It mediates vascular contraction

Explanation

Question 6 of 29

1

Which of following statements properly concern eosinophils?

Select one or more of the following:

  • They migrate in large number into tissues infected by parasites where they release hydrolytic enzymes

  • They release heparin, histamine as well as small quantities of bradykinin and serotonin

  • They belong to the adaptive immune system. They are not able to phagocyte

  • They aggregate in tissues where allergic reactions occur, (peribronchial tissue in people with asthma).

  • They exhibit chemotaxis

Explanation

Question 7 of 29

1

Which of following statements concern G-protein coupled receptors?

Select one or more of the following:

  • G-protein coupled receptors hydrolyses GTP, transferred from G-protein to the binding site of the receptor

  • Muscarinic receptor is an example of G-protein coupled receptor

  • All adrenergic receptors belong to family of G-protein coupled receptors

  • G-protein coupled receptors are metabotropic, they initiate formation of second messengers: cAMP or IP3

Explanation

Question 8 of 29

1

Actions of Heparin are:

Select one or more of the following:

  • it inhibits activity of plasma coagulation factors I and IV.

  • it activates natural anticoagulant protein of plasma- antithrombin III

  • it inhibits activity of activated Stuart factor and thrombin (factors X and II)

  • It intensifies adhesion and degranulation of platelets

  • It intensifies proteolytic degradation of plasminogen

Explanation

Question 9 of 29

1

Which of following receptors are ionotropic receptor for cations?

Select one or more of the following:

  • IP3 receptor

  • Ryanodine receptor

  • Glycine receptors

  • GABAA receptor

  • Nicotinic receptor

Explanation

Question 10 of 29

1

10. Put following cations of the extracellular fluid ECF in proper order;
Being from the most concentrated;
Select one;

Select one or more of the following:

  • Magnesium-sodium-calcium

  • Potassium-sodium-calcium-magnesium

  • Potassium-calcium-magnesium-sodium

  • Sodium- potassium-calcium-magnesium

  • Sodium -calcium- potassium- magnesium

Explanation

Question 11 of 29

1

Which of following sentences are true?

Select one or more of the following:

  • immunoglobulins against antigen D of Rhesus system develop in childhood

  • Immediately after birth the quantify of agglutins in the plasma of the newborn is almost zero

  • Immunoglobulins against ABO blood type is produced by the fetus before their birth

  • Agglutinins in ABO system are produced in effect of immunization against antigens A and B commonly present in environment

Explanation

Question 12 of 29

1

Muraminidase: = Lysozyme

Select one or more of the following:

  • it is a part of innate immune response

  • It activates complement cascade

  • It is an enzyme that performs bacterial lysis

  • It is present in plasmocytes

Explanation

Question 13 of 29

1

Find right sentences concerning transportation of CO2 in blood;

Select one or more of the following:

  • 5-7% of all the CO2 is transported physically dissolved in blood

  • 50% of C02 is converted to bicarbonate. Process is catalyzed angiotensin converting enzyme.

  • All the bicarbonate produced in erythrocytes and exchanged for chloride. It is called Hamburger’s phenomenon.

  • Part of CO2 is reversibly bound to hemoglobin, forming carboxyhemoglobin

Explanation

Question 14 of 29

1

In Rhesus system of blood;

Select one or more of the following:

  • D antigen the oligosaccharide bound to the cellular membrane

  • D antigen is the most immunogenic (the strongest component of the system

  • All antigens of the Rhesus system are proteins located only on membranes of erythrocytes

  • Agglutinins are synthesized in RhD-negative individuals after exposure to RhD- positive blood

Explanation

Question 15 of 29

1

Which of following events DO NOT match the signal transduction of G protein coupled receptor.

Select one or more of the following:

  • Autophosphorylation of tyrosine residues of B-subunit of the receptor B-subunit phosphorylates other proteins

  • Binding of the ligand to its native receptor, receptor activates

  • Receptor interacts with G protein to promote a conformational change and the exchange of GDP to GTP

  • Subunits of G protein interact with their appropriate enzymes, activating various second messenger pathways and other effector proteins

Explanation

Question 16 of 29

1

16. Which of following results of blood tests may suggest improperly low activity/ concentration of thrombin?

Select one or more of the following:

  • prolonged time of the clotting time test

  • prolonged prothrombin time

  • prolonged time of bleeding time test

  • prolonged time of Rumpel-Leede test

Explanation

Question 17 of 29

1

Oxytocin

Select one or more of the following:

  • it produces contraction of cells of the deferent duct

  • it upregulates synthesis IP3 in smooth muscle cells of the uterus

  • It is responsible for milk ejection due to contraction of myoepithelial cells

  • It has galactopoietic activity- it stimulates production of milk

Explanation

Question 18 of 29

1

Action of glucocorticoids (cortisol) are;

Select one or more of the following:

  • rise of liberation of histamine from mast cells

  • rise of gluconeogenesis

  • rise of plasma concentration free fatty acids

  • intensification of catecholamine dependant bronchodilation

Explanation

Question 19 of 29

1

Which of following statements concerning coagulation are proper:

Select one or more of the following:

  • Thrombin dependent factors are factors I, II, X and XII

  • Thrombin is a proteolytic enzyme catalyzing conversion of fibrinogen into fibrin.

  • Vitamin K is necessary in process of post-translatory modification of prothrombin in liver.

  • Exposition of thrombin to fibrin degradation products accelerate coagulation

Explanation

Question 20 of 29

1

Hemoglobin-oxygen dissociation curve shifts to the left due to: left = increased affinity

Select one or more of the following:

  • Decline of the temperature.

  • Rise of 2,3 BPG.

  • Impulses from carotid bodies.

  • Rise of pH.

  • Hypercapnia (rise of pCO2)

Explanation

Question 21 of 29

1

Actions of heparin are:

Select one or more of the following:

  • It inhibits activity of plasma coagulation factors I and IV.

  • It activates natural anticoagulant protein of plasma – antithrombin III.

  • It inhibits activity of activated Stuart factor and thrombin (factors X and II).

  • It intensifies adhesion and degranulation of platelets.

  • It intensifies proteolytic degradation of plasminogen.

Explanation

Question 22 of 29

1

Find true statements concerning vasopressin:

Select one or more of the following:

  • It increase water reabsorption from the collecting duct via AQP2 up-regulated after hormone binds to VP1 receptor

  • In smooth musculature of vessels, it up-regulates synthesis of IP3 in smooth muscle cells, eliciting contraction.

  • It’s plasma level rises in effect of decreasing osmotic pressure of blood and cerebrospinal fluid.

  • Decompression of baroreceptors of the carotid sinus and aortic arch increases liberation of that hormone.

  • It inhibits complex of thirst.

Explanation

Question 23 of 29

1

Which of following sentences are true?

Select one or more of the following:

  • 5-7 % of all the CO2 is transported physically dissolved in blood.

  • 40 % of CO2 is converted to bicarbonate. Process is catalyzed carbonic anhydrase

  • Part of CO2 is reversibly bound to hemoglobin, such a molecule is called carbaminohemoglobin.-

  • All the bicarbonate produced in erythrocytes is exchanged for phosphate. It’s called Hamburger’s phenomenon

Explanation

Question 24 of 29

1

Which of following statements properly describe characteristics of facilitated diffusion?

Select one or more of the following:

  • in facilitated diffusion, membrane carriers enable movement of molecules through the cellular membrane against concentration gradient

  • Particular membrane carrier is able to transfer one particular type of molecules soluble in water.

  • Facilitated diffusion characterizes with finite rate of transfer of substance defined as maximum saturation.

  • Water molecules pass from the cell of the collecting duct to its lumen through the system of facilitated diffusion called AQP2

Explanation

Question 25 of 29

1

Lactoferrin:

Select one or more of the following:

  • It is a part of innate immune response.

  • It activates complement cascade.

  • It is an enzyme of saliva binding iron necessary for proliferation of microbs.

  • It is an enzyme of saliva reducing Fe2+ toFe3+.

Explanation

Question 26 of 29

1

Which of following receptors are intracellular ionotropic receptor for cations?

Select one or more of the following:

  • P3 receptor.

  • Ryanodine receptor.

  • Glycine receptors.

  • GABAA receptor

  • Nicotinic receptors.

Explanation

Question 27 of 29

1

Action of glucocorticoids (cortisol) are:

Select one or more of the following:

  • It up-regulates liberation of histamine from mast cells.

  • It intensifies gluconeogenesis in liver.

  • It down-regulates number of lymphocytes and eosinophils.

  • It intensifies catecholamine-dependent bronchoconstriction

  • It increases GFR

Explanation

Question 28 of 29

1

Which of following statements properly describes beta-adrenergic (β-adrenergic) receptors?

Select one or more of the following:

  • β-adrenergic receptor is a ligand-gated channels.

  • Activity of some adrenergic receptors brings fEPSP to the postsynaptic membranes.

  • Beta-adrenergic receptors initiate transduction resulting with activation of adenylate cyclase.

  • Activation of beta -adrenergic receptors up-regulates synthesis of cAMP.

Explanation

Question 29 of 29

1

Put following cations of the extracellular fluid (ECF) in proper order. Begin from the least concentrated:

Select one or more of the following:

  • Sodium-potassium-calcium- magnesium

  • Sodium- calcium - potassium - magnesium

  • Potassium-sodium-calcium- magnesium

  • Magnesium-calcium-potassium-sodium

Explanation