Ifeoma Okekearu
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Schizophrenia

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Ifeoma Okekearu
Created by Ifeoma Okekearu over 8 years ago
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Neuro Pharmacology - Schizophrenia

Neuro Pharmacology - Schizophrenia

Question 1 of 13

1

What are the criteria for a schizophrenia diagnosis?

Select one of the following:

  • Positive Schizophrenic Symptoms

  • Disorganized Speech/ Thoughts

  • Negative Schizophrenic Symptoms

  • Symptoms lasting > 6 months

  • All of the choices are correct

Explanation

Question 2 of 13

1

Most cognitive symptoms in schizophrenia are correlated with dysfunctions of the mesolimbic system.

Select one of the following:

  • True
  • False

Explanation

Question 3 of 13

1

Which of the following are structural abnormalites are found in the brians of schizophrenic patients.

Select one or more of the following:

  • Lateral and Third Ventricular Enlargement

  • Volume Increases of the Prefrontal and Oribitofrontal Cortex

  • Abnormalities of the Basal Ganglia

  • Volume Reduction of the Temporal Lobe

Explanation

Question 4 of 13

1

NMDA Glutamate receptor activation will produce "schizophrenia-like" symptoms in healthy adults.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 13

1

Select all of the statements that are prodromal signs/symptoms of schizophrenia.

Select one or more of the following:

  • Sudden development of interest in abstract ideas.

  • Decline is occupational and interpersonal functioning.

  • Quiet, passive, introverted personality

  • Delusions and Hallucinations

Explanation

Question 6 of 13

1

Schizophrenia is sa neurodegenerative disorder

Select one of the following:

  • True
  • False

Explanation

Question 7 of 13

1

Architectural changes are often involved in certain regions of the brains of schizophrenic patients. These same regions become vey active during episodes of hallucination. Which regions below would an MRI show activity during a hallucination?

Select one or more of the following:

  • Temporal Lobe

  • Prefrontal Cortex

  • Occipital Lobe

  • Parietal Lobe

  • Hippocampus

Explanation

Question 8 of 13

1

Select the statement(s) below that is/are involved in the manifestations of schizophrenic symptoms.

Select one of the following:

  • Schizophrenia patients usually have over-activity of the dopamine D2 receptors.

  • 5-HT2A Receptors are involved in the pathogenesis of schizophrenia

  • Blockage of NMDA glutamate mimic all schizophrenic symptoms suggesting schizophrenic patients have a deficiency in these receptors.

  • All of the above

  • None of the above

Explanation

Question 9 of 13

1

NMDA receptors require multiple stimuli to converge in order for them to become activated.

Select one of the following:

  • True
  • False

Explanation

Question 10 of 13

1

Which statement about the glutaminergic hypothesis of schizophrenia is true?

Select one of the following:

  • There is hyperactivity of the mesolimbic system and hypoactivity of the mesocortical system.

  • There is hypoactivity of the mesolimbic system and hypoactivity of the mesocortical system.

  • There is hyperactivity of the mesolimbic system and hyper activity of the mesocortical system.

  • There is hypoactivity of the mesolimbic system and hyperactivity of the mesocortical system.

Explanation

Question 11 of 13

1

What effect would blockage of the dopamine D2 receptors in the CTZ have on a patient?

Select one of the following:

  • Parkinsonism

  • Tardive Dyskinesia

  • Anti-Emetic

  • Hypothermia

  • None of the above

Explanation

Question 12 of 13

1

Which option below would NOT be a side effect of the use anticholinergics?

Select one or more of the following:

  • Nausea

  • Tachycardia

  • Constipation

  • Blurry Vision

Explanation

Question 13 of 13

1

What is the course of action for the treatment of a psychotic patient that develops the rare Neuroleptic Malignant Syndrome

Select one or more of the following:

  • Stop Anti-Psychotic drug, IV Dantrolene, IV Normal Saline, & Bromocriptine

  • Increase Anti-Psychotic drug, PO Dantrolene, Heating Pads, Diphenhydramine

  • Stop Antipsychotic, Injected Diazepam, IV Fluids, Inject Bromocriptine

Explanation

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