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Metabolism of cholesterol test

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LESSON 28: METABOLISM OF CHOLESTEROL

Question 1 of 11

1

Cholesterol is the precursor of...?

Select one of the following:

  • 1.) Bile acids

  • 2.) Hormones

  • 3.) Vitamine D

  • Only 1.) and 2.) are true

  • All are true

Explanation

Question 2 of 11

1

Cholesterol can not be degraded

Select one of the following:

  • True
  • False

Explanation

Question 3 of 11

1

Which of these is not true?

Select one of the following:

  • The substrates for the synthesis of cholesterol are AcetylCoA, ATP and NADPH

  • 30 reactions occur in cholesterol synthesis

  • The regulation of the synthesis takes place in the first step

  • Synthesis of cholesterol happens in a fasting state

  • Synthesis of cholesterol will take place in liver in the cytosol

Explanation

Question 4 of 11

1

Which enzyme can be blocked using statins leading to a regulation in the production of mevalonic acid?

Select one of the following:

  • Thiolase

  • HMG-CoA synthase

  • HMG-CoA reductase

  • Squalene synthase

  • Prenyl transferase

Explanation

Question 5 of 11

1

Which molecule or molecules is/are inhibitors of the synthesis of cholesterol?

Select one of the following:

  • Cholesterol

  • Glucagon

  • NADPH

  • ATP

  • Glucagon and cholesterol

Explanation

Question 6 of 11

1

What is found in the surface of a lipoprotein?

Select one of the following:

  • Cholesterol esters and triglycerides

  • Proteins, phospholipids (the head) and the hydroxyl group of cholesterol

  • The hydroxyl group of cholesterol

  • Proteins and triglycerides

  • Cholesterol esters, triglycerides and proteins

Explanation

Question 7 of 11

1

Which is the biggest lipoprotein?

Select one of the following:

  • Chylomicrons

  • VLDL's

  • IDL's

  • LDL's

  • HDL's

Explanation

Question 8 of 11

1

Which lipoprotein transport phospholipids?

Select one of the following:

  • Chylomicrons

  • VLDL's

  • IDL's

  • LDL's

  • HDL's

Explanation

Question 9 of 11

1

If the levels of HDL cholesterol are higher that the levels of LDL this means that you have more bad cholesterol and you are deporting more cholesterol from liver to the tissues than the cholesterol that is transported from the tissues to the liver

Select one of the following:

  • True
  • False

Explanation

Question 10 of 11

1

Which of these statements is true?

Select one of the following:

  • Any of these

  • Lipoprotein lipase is responsible for the transformation of Fatty Acids and glycerol into TG

  • Lipoprotein lipase is responsible for the transformation of TG and glycerol into Fatty Acids

  • Lipoprotein lipase is responsible for the transformation of Fatty Acids into TG and glycerol

  • Lipoprotein lipase is responsible for the transformation of Glycerol into Fatty Acids and TG

Explanation

Question 11 of 11

1

What could happen if you find high levels of chylomicrons in a clinical analysis?

Select one of the following:

  • The patient is in a fasting state

  • The patient is in a fed state

  • The patient could have a disorder due to the endogenous pathway

  • The patient could have a disorder due to the reverse transport of cholesterol

  • Any of these

Explanation