Cardiovascular System (Part 1 - Anatomy and Antithrombotics)

Question 1 of 63

1

Fill the blank spaces to complete the text.

The heart and blood vessels transport , , , and around the body rapidly

Explanation

Question 2 of 63

1

Fill the blank spaces to complete the text.

What are the four functions of the CV system?
1.
2.
3.
4.

Explanation

Question 3 of 63

1

Fill the blank space to complete the text.

What is the maximum distance diffusion can occur over? (in micrometers)

Explanation

Question 4 of 63

1

What is the rate at which blood is pumped around the body? (in cm per second)

Select one of the following:

10
5
15
3
8

Explanation

Question 5 of 63

1

Fill the blank spaces to complete the text.

The heart has two pumps. The right and left

Explanation

Question 6 of 63

1

Fill the blank space to complete the text.

The ventricles are filled from reservoirs, also known as the right and left .

Explanation

Question 7 of 63

1

The ❌ pumps ❌ blood through the ❌. ❌ ❌ veins return oxygenated blood from the lungs to the ❌ side of the heart. This is called ❌.

Drag and drop to complete the text.

right ventricle

left ventricle

right atrium

left atrium

deoxygenated

oxygenated

heart to the lungs

lungs to the heart

Four

Five

Three

Two

pulmonary

artery

lung

long

left

right

pulmonary circulation

systemic circulation

Explanation

Question 8 of 63

1

What is roughly the pressure at which blood is pumped from the heart to the lungs? (in mmHg)

Select one of the following:

20
15
65
80
25

Explanation

Question 9 of 63

1

What is roughly the pressure at which blood is pumped from the heart through the aorta? (in mmHg)

Select one of the following:

20
65
15
90
70

Explanation

Question 10 of 63

1

Fill the blank spaces to complete the text.

Blood is pumped to the body to tissues, and partly blood is returned to the heart via two veins. The and vena cava.

Explanation

Question 11 of 63

1

Fill the blank space to complete the text.

When blood returns to the heart via two veins, this is known as circulation.

Explanation

Question 12 of 63

1

The right ventricle has a greater muscle mass than the left ventricle because it pumps blood at a higher pressure (to all the body).

Select one of the following:

True
False

Explanation

Question 13 of 63

1

The ❌ are composed mainly of cardiac muscle, and fill with blood while the muscle is ❌.
Relaxation is known as ❌, and contraction is known as ❌.

Drag and drop to complete the text.

ventricles

atria

relaxed

contrated

diastole

pumping

systole

filling

stretching

Sistol

diastolic

systolic

Explanation

Question 14 of 63

1

Fill the blank space to complete the text.

If heart rate is between 60-75 bpm, and the stroke volume is 70-80ml... what will be the cardiac output? (in L/min)
L/min

Explanation

Question 15 of 63

1

❌ = ❌ x ❌

Drag and drop to complete the text.

Mean arterial pressure

Density of blood

Stroke volume

Height of fluid

Cardiac output

Blood volume

Total peripheral resistance

Resistance of vessel

Explanation

Question 16 of 63

1

Cardiac output can increase greatly in response to increased peripheral oxygen demand, rising 10 to 12 fold during strenuous human exercise.

Select one of the following:

True
False

Explanation

Question 17 of 63

3

Fill the blank spaces to complete the text.

Blood pressure definition = The exerted by on the walls of the .

Explanation

Question 18 of 63

1

Because blood pressure is different in different areas of the body, what type of blood pressure is stated?

Select one of the following:

convective
pulmonary vein
pulmonary artery
systemic venule
system arterial
systemic arterial
systemic

Explanation

Question 19 of 63

1

Fill the blank spaces to complete the text.

The circulation of blood is in a arrangement. This means it is divided into circuits, each supplying a specialised tissue/organ.

Explanation

Question 20 of 63

1

The ❌ branch from the heart is called ❌. This means blood is supplied to the heart itself.

Drag and drop to complete the text.

first

second

third

last

coronary circulation

pulmonary circulation

systemic circulation

blood pressure

myogenic circulation

myocyte

arteriole circulation

Explanation

Question 21 of 63

1

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The left ventricular output is distributed to the tissues of the body in proportion to their metabolic rate. The muscle takes 20% of O2 consumption at rest and receives 20% of the cardiac output.
This is different in the because its function requires a blood flow. This causes other tissues to receive less e.g. . To compensate, it extracts an unusually proportion of the O2 (~%), whereas normal = ~%. It is very at taking from blood.

Explanation

Question 22 of 63

1

Venules and small veins are more numerous than arterioles and arteries.

Select one of the following:

True
False

Explanation

Question 23 of 63

1

Because of their large number and size, veins and venules contain about a 1/2 of circulating blood.

Select one of the following:

True
False

Explanation

Question 24 of 63

1

Veins and venules are known as ______ vessels.

Select one of the following:

capacitance
large
resistance
returning
deoxygenated

Explanation

Question 25 of 63

1

Systemic arteries are known as resistance vessels

Select one of the following:

True
False

Explanation

Question 26 of 63

1

Fill the blank space to complete the text.

Drugs that act on the blood are called drugs

Explanation

Question 27 of 63

1

There are three types of antithrombotic drugs. What are the classes called?

Select one or more of the following:

antiplatelet
coagulants
platelet drugs
anticoagulants
thrombolytic
antithrombolytic

Explanation

Question 28 of 63

1

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A is a blood clot that forms in a vessel and remains there.

Explanation

Question 29 of 63

1

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An is a clot that travels from the site where is formed to another in the body.

Explanation

Question 30 of 63

1

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Name three antiplatelet drugs.
1.
2.
3.

Explanation

Question 31 of 63

1

Fill the blank spaces to complete the text.

Name three anticoagulants.
1.
2.
3.

Explanation

Question 32 of 63

1

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Name two thrombolytic drugs.
1.
2.

Explanation

Question 33 of 63

1

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In terms of a cut, homeostasis is the and bleeding. This results in a and the bleeding .

Explanation

Question 34 of 63

1

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Blood clot formation.
Step 1 = - this is triggered by cells
Step 2 = - Platelets together and temporarily stop the blood flow. This is the stage where antiplatelets act on.
Step 3 = - Conversion of to ). The insoluble forms a around the platelet plug (causing platelets to to each other).

Explanation

Question 35 of 63

1

Antiplatelet drugs act on the venous system

Select one of the following:

True
False

Explanation

Question 36 of 63

1

Anticoagulant drugs act on the arteriole system

Select one of the following:

True
False

Explanation

Question 37 of 63

1

Anticoagulant drugs act on the venous system

Select one of the following:

True
False

Explanation

Question 38 of 63

1

Antiplatelet drugs can be used for what conditions?

Select one or more of the following:

Acute myocardial infarction
Unstable coronary syndromes
Transient ischaemic attacks
Atrial fibrillation
Secondary prevention of CV events
Angina
Blood clot
Primary prevention of CV events
Hypertension

Explanation

Question 39 of 63

1

Click on each orange point and write the correct answer.

Platelet formation

Explanation

Question 40 of 63

1

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and are which bind to collagen and (vWF), causing platelets to adhere to the of a damaged blood vessel.

Explanation

Question 41 of 63

1

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PAR1 and are receptors that respond to (IIa)

Explanation

Question 42 of 63

1

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and are receptors for ADP. When stimulated by , they activate GPIIa/IIIa and (COX-1) to promote platelet .

Explanation

Question 43 of 63

1

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is a major product of COX-1 involved in . It is involved in the feedback process. It signals to join and become .

Explanation

Question 44 of 63

3

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is synthesised by cells. It inhibits platelet activation. It is found naturally in the body, and is part of a feedback process of platelet aggregation - it slows the process down.

Explanation

Question 45 of 63

1

What three drugs are used to inhibit GPIIb/IIIa receptor?

Select one or more of the following:

Aspirin
Clopidogrel
Tirofiban
Eptifibadite
Warfarin
Cangelor
Abciximab

Explanation

Question 46 of 63

1

What four drugs are used to inhibit the GPIa/IIa receptor?

Select one or more of the following:

Cangelor
Clopidogrel
Aspirin
Tirofiban
Ticlopidine
Abciximab
Prasugrel

Explanation

Question 47 of 63

1

Fill the blank spaces to complete the text.

Aspirin is a inhibitor of receptors.

Explanation

Question 48 of 63

1

Warfarin is a vitamin K antagonist

Select one of the following:

True
False

Explanation

Question 49 of 63

1

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Warfarin works by the regeneration of the form of vitamin

Explanation

Question 50 of 63

1

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Vitamin is philic, and is required for the of certain blood . Vitamin K is essential for the synthesis of factors , , , and X.

Explanation

Question 51 of 63

1

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Warfarin the conversion of oxidised vitamin K into its form, Vitamin K .

Explanation

Question 52 of 63

1

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Heparin are a family of glycans.

Explanation

Question 53 of 63

1

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Heparin activates , and inactivates coagulant factors and .

Explanation

Question 54 of 63

1

Heparin is given orally.

Select one of the following:

True
False

Explanation

Question 55 of 63

1

What are the two types of heparin?

Select one or more of the following:

LMWH
Fractionated heparin
Dalteparin
Unfractionated heparin
LWMH
Thrombin Inhibitors

Explanation

Question 56 of 63

1

Give four examples of LMWH (Low Molecular Weight Heparin)

Select one or more of the following:

Bemiparin
Semiparin
Coxiparin
Dalteparin
Foxiparin
Enoxaparin
Tinzaparin

Explanation

Question 57 of 63

1

Fill the blank spaces to complete the text.

LMWH are than unfractionated heparin because they have a effect on platelet activation and a reported incidence of heparin induced - this is there is a deficiency of platelet in the blood which causes bleeding in the tissues and slow blood clotting.

Explanation

Question 58 of 63

1

Fill the blank spaces to complete the text.

Name three thrombin inhibitors.
1.
2.
3. Dabigatran

Explanation

Question 59 of 63

1

Anticoagulants are used for the prevention of:

Select one or more of the following:

DVT
Extension of established DVT
Transient ischaemic attack
Clotting during dialysis
Myocardial infarction (in unstable angina)
Myocardial infarction (in stable angina)
Atrial fibrillation
Pulmonary embolus

Explanation

Question 60 of 63

1

Fill the blank spaces to complete the text.

INR = () to the power of

Explanation

Question 61 of 63

1

Fill the blank spaces to complete the text.

is the breakdown of fibrin once it has already formed.
is the factor that breaks down fibrin.
Endothelial cells secrete tissue activator (t-PA) at sites of injury. t-PA binds to and converts to , which digests fibrin. activator inhibitors- and - (PAI-, PAI-) inactivate t-PA; α2-antiplasmin (α2-AP) inactivates plasmin.

Explanation

Question 62 of 63

1

Streptokinase is a protein derived from streptococci which inactivates plasminogen

Select one of the following:

True
False

Explanation

Question 63 of 63

1

What are the uses of fibrinolytics?

Select one or more of the following:

Acute myocardial infarction (within 12 hours of onset)
Chronic myocardial infarction
Acute myocardial infarction (within 24 hours)
Acute myocardial infarction
Acute thrombotic stroke
Atrial fibrillation
DVT
Acute arterial thromboembolism
Pulmonary embolism
Hypertension

	Created by sbpharmacy about 8 years ago

Aimed at Pharmacy students

Cardiovascular System (Part 1 - Anatomy and Antithrombotics)

Question 1 of 63

Fill the blank spaces to complete the text.

The heart and blood vessels transport , , , and around the body rapidly

Explanation

Question 2 of 63

Fill the blank spaces to complete the text.

What are the four functions of the CV system? 1. 2. 3. 4.

Explanation

Question 3 of 63

Fill the blank space to complete the text.

What is the maximum distance diffusion can occur over? (in micrometers)

Explanation

Question 4 of 63

What is the rate at which blood is pumped around the body? (in cm per second)

Select one of the following:

Explanation

Question 5 of 63

Fill the blank spaces to complete the text.

The heart has two pumps. The right and left

Explanation

Question 6 of 63

Fill the blank space to complete the text.

The ventricles are filled from reservoirs, also known as the right and left .

Explanation

Question 7 of 63

The ❌ pumps ❌ blood through the ❌. ❌ ❌ veins return oxygenated blood from the lungs to the ❌ side of the heart. This is called ❌.

Drag and drop to complete the text.

Explanation

Question 8 of 63

What is roughly the pressure at which blood is pumped from the heart to the lungs? (in mmHg)

Select one of the following:

Explanation

Question 9 of 63

What is roughly the pressure at which blood is pumped from the heart through the aorta? (in mmHg)

Select one of the following:

Explanation

Question 10 of 63

Fill the blank spaces to complete the text.

Blood is pumped to the body to tissues, and partly blood is returned to the heart via two veins. The and vena cava.

Explanation

Question 11 of 63

Fill the blank space to complete the text.

When blood returns to the heart via two veins, this is known as circulation.

Explanation

Question 12 of 63

The right ventricle has a greater muscle mass than the left ventricle because it pumps blood at a higher pressure (to all the body).

Select one of the following:

Explanation

Question 13 of 63

The ❌ are composed mainly of cardiac muscle, and fill with blood while the muscle is ❌. Relaxation is known as ❌, and contraction is known as ❌.

Drag and drop to complete the text.

Explanation

Question 14 of 63

Fill the blank space to complete the text.

If heart rate is between 60-75 bpm, and the stroke volume is 70-80ml... what will be the cardiac output? (in L/min) L/min

Explanation

Question 15 of 63

❌ = ❌ x ❌

Drag and drop to complete the text.

Explanation

Question 16 of 63

Cardiac output can increase greatly in response to increased peripheral oxygen demand, rising 10 to 12 fold during strenuous human exercise.

Select one of the following:

Explanation

Question 17 of 63

Fill the blank spaces to complete the text.

Blood pressure definition = The exerted by on the walls of the .

Explanation

Question 18 of 63

Because blood pressure is different in different areas of the body, what type of blood pressure is stated?

Select one of the following:

Explanation

Question 19 of 63

Fill the blank spaces to complete the text.

The circulation of blood is in a arrangement. This means it is divided into circuits, each supplying a specialised tissue/organ.

Explanation

Question 20 of 63

The ❌ branch from the heart is called ❌. This means blood is supplied to the heart itself.

What are the four functions of the CV system?
1.
2.
3.
4.

The ❌ are composed mainly of cardiac muscle, and fill with blood while the muscle is ❌.
Relaxation is known as ❌, and contraction is known as ❌.

If heart rate is between 60-75 bpm, and the stroke volume is 70-80ml... what will be the cardiac output? (in L/min)
L/min

Name three antiplatelet drugs.
1.
2.
3.

Name three anticoagulants.
1.
2.
3.

Name two thrombolytic drugs.
1.
2.

Blood clot formation.
Step 1 = - this is triggered by cells
Step 2 = - Platelets together and temporarily stop the blood flow. This is the stage where antiplatelets act on.
Step 3 = - Conversion of to ). The insoluble forms a around the platelet plug (causing platelets to to each other).