DNA In Protein Synthesis -The Genetic Code

Question 1 of 32

1

In stage one of the process by which the information of the gene is used to determine how the protein molecule is constructed, a copy of the code is made by building a molecule of mRNA which is catalysed by RNA polymerase, involving complementary base paring with the antisense strand as a template. The mRNA strand then leaves the nucleus through pores in the nuclear membrane and passes to the ribosomes in the cytoplasm to be 'read'.

Select one of the following:

True
False

Explanation

Question 2 of 32

1

The second stage of protein synthesis occurs in the ribosomes in the cytoplasm, and AAs are activated for protein synthesis by combining with short lengths of tRNA, with a different tRNA for each of the 20 AAs. One end of each tRNA molecule is a site where a particular AA can attach and at the other end there is an anticodon.

Select one of the following:

True
False

Explanation

Question 3 of 32

1

Anticodons are made up of a sequence of 3 bases which are complementary to the the codon of mRNA that codes for the specific AA.

Select one of the following:

True
False

Explanation

Question 4 of 32

1

Translation is stage 3 and occurs in the ribosomes in the cytoplasm, where a protein is assembled one AA residue at a time as a ribosome moves along the mRNA reading the codons.

Select one of the following:

True
False

Explanation

Question 5 of 32

1

Complementary anticodons of the AA-tRNA slot into place and are temporarily held in position by hydrogen bonds. While there the AAs of neighbour AA-tRNAs are joined by peptide linkages.

Select one of the following:

True
False

Explanation

Question 6 of 32

1

Genes function (are expressed) only in cells they relate to, when they are needed.

Select one of the following:

True
False

Explanation

Question 7 of 32

1

In eukaryotes, genes are only transcribed if an RNA polymerase enzyme binds to a region of DNA situated close to the gene known as a ___ .

Select one of the following:

promoter
expressor
transcriber

Explanation

Question 8 of 32

1

What are the special features of promoters in eukaryotic chromosomes?

Select one or more of the following:

some permit repeated, unrestricted binding of RNA polymerase, resulting in continuous expression of a gene
some require a regulatory protein to be present and bound, prior to binding of RNA polymerase & gene expression
some regulatory proteins must first be activated by reaction with a steroid hormone or some other metabolite, before binding of RNA polymerase & gene expression
some do not permit binding of RNA polymerase, resulting in no expression of specific genes.

Explanation

Question 9 of 32

1

The steps of the expression of a gene begin when the genetic informaiton in DNA is transcribed into a molecule of mRNA by complementary base paring. The RNA polymerase binds to a promoter region (the 'start' signal for transcription) located immediately before the gene.

Select one of the following:

True
False

Explanation

Question 10 of 32

1

Highlight the characteristics that apply to the sense strand and leave the once that apply to the antisense strand blank.

Select one or more of the following:

Carriers the promoter sequence of bases to which RNA polymerase binds and begins transcription.
Has the same base sequence as the mRNA.
Carries the terminator sequence of bases at the termination of each gene that causes RNA polymerase to stop transcription.
Is the template sequence for transcription by complementary base paring by RNA polymerase.
Has the same base sequence as the tRNA.
Is read in the '5 -> 3' direction and mRNA synthesis occurs in the opposite direction.

Explanation

Question 11 of 32

1

RNA polymerase draws on a pool of free nucleotides.

Select one of the following:

True
False

Explanation

Question 12 of 32

1

As the RNA trand is formed, it falls away from the antisense strand and hydrogen bonds re-form between the two DNA strands. The process continues until a base sequence known as the inhibitor is reached, causing both RNA polymerase and the completed mRNA strand to be freed from the site of the gene.

Select one of the following:

True
False

Explanation

Question 13 of 32

1

The sections of DNA that carry meaningful information are called introns and the intervening lengths f DNA are called exons.

Select one of the following:

True
False

Explanation

Question 14 of 32

1

When a split gene is transcribed into mRNA, the sequence of introns continues to exist exactly as it occurred in the DNA, and so an enzyme catalysed reaction known as ___ removes the introns to shorten the length of mRNA which is now described as mature before it moves out into the cytoplasm.

Select one of the following:

post-transcriptional modification
pre-transcriptional modification
post-prescribed modification

Explanation

Question 15 of 32

1

The AA activation process by ehich AA are combined with tRNA occurs in the cytoplasm and requires ATP.

Select one of the following:

True
False

Explanation

Question 16 of 32

1

It is this tRNA, once attached to its AA, which facilitates the translation of the three-base sequences of each codon of mRNA into a sequence of AAs in a protein.

Select one of the following:

True
False

Explanation

Question 17 of 32

1

The codon located on one end of the tRNA is complementary to the codon of mRNA that codes for that specific AA.

Select one of the following:

True
False

Explanation

Question 18 of 32

1

An AA is attached to its tRNA by enzyme action specific to that AA, which allows recognition by a specific tRNA activating enzyme which attaches a specific AA to the tRNA and ensure they'r ein the right sequence.

Select one of the following:

True
False

Explanation

Question 19 of 32

1

Translation occurs in the ribosomes which are organelles made up of a large and small subunit which are both composed of _ and protein. During translation, the mRNAs bind with the _ subunit where also occur the three sites where the tRNA's interact.

Select one of the following:

rRNA | small
mRNA | big
tRNA | small

Explanation

Question 20 of 32

1

At the 1st site, codons of the incoming tRNA bind to specific tRNA AAs through their anticodons by complementary base paring.

Select one of the following:

True
False

Explanation

Question 21 of 32

1

At the 2nd site, the tRNA leaves the ribosome following transfer of its AA to the growing protein chain.

Select one of the following:

True
False

Explanation

Question 22 of 32

1

At the 3rd site, the AA attached to its tRNA is condensed with the growing polypeptide chain by formation of a peptide linkage.

Select one of the following:

True
False

Explanation

Question 23 of 32

1

The structure of mRNA, ribosomes and their growing protein chain, is called a polyphosphome.

Select one of the following:

True
False

Explanation

Question 24 of 32

1

Other ribosomes that synthesis proteins to be excreted from the cell or packages in lysosomes are located where?

Select one of the following:

bound to the membranes of the rER.
bound to the membranes of the sER.

Explanation

Question 25 of 32

1

post-transcriptional modifications refer to processing steps that some proteins (inactive precursors) needs to go through in order to be activated.

Select one of the following:

True
False

Explanation

Question 26 of 32

1

post-transcriptional modifications refer to processing steps that some proteins (inactive precursors) needs to go through in order to be activated.

Select one of the following:

True
False

Explanation

Question 27 of 32

1

The central dogma of molecular biology refers to the one-way flow of coded information from the nucleus to the cytoplasm.

Select one of the following:

True
False

Explanation

Question 28 of 32

1

An exception to the central dogma of molecular biology is the enzyme secreted by the HIV nucleic acid -reverse transcriptase, which catalyses the copying of the RNA strand to form a DNA double helix which enters the host nucleus and becomes attached to a hsot chromosome.

Select one of the following:

True
False

Explanation

Question 29 of 32

1

Reverse-transcriptase can be extracted from retroviruses and used in genetic modification for the synthesis of a DNA strand, complementary to an existing RNA strand.

Select one of the following:

True
False

Explanation

Question 30 of 32

1

DNA ligase occurs with nucleic acid in the nucleus of all organisms and is used for..

Select one of the following:

joining together DNA molecules during replication of DNA.
breaking DNA into shorter lengths.

Explanation

Question 31 of 32

1

Polymerase occurs in the same place as ligase and is used for..

Select one of the following:

synthesising nucleic acid strands, guided by an antisense strand of nucleic acid.
synthesising DNA strands complementary to an existing RNA strand.

Explanation

Question 32 of 32

1

Restriction enzymes found in the cytoplasm of bacteria can be used for breaking DNA molecules into shorter lengths at specific nucleotide sequences.

Select one of the following:

True
False

	Created by cloud.berry almost 10 years ago

IBD Biology (Unit 8 : Nucleic Acids & Proteins) Quiz on DNA In Protein Synthesis -The Genetic Code, created by cloud.berry on 07/05/2014.

DNA In Protein Synthesis -The Genetic Code

Question 1 of 32

Select one of the following:

Explanation

Question 2 of 32

Select one of the following:

Explanation

Question 3 of 32

Anticodons are made up of a sequence of 3 bases which are complementary to the the codon of mRNA that codes for the specific AA.

Select one of the following:

Explanation

Question 4 of 32

Translation is stage 3 and occurs in the ribosomes in the cytoplasm, where a protein is assembled one AA residue at a time as a ribosome moves along the mRNA reading the codons.

Select one of the following:

Explanation

Question 5 of 32

Complementary anticodons of the AA-tRNA slot into place and are temporarily held in position by hydrogen bonds. While there the AAs of neighbour AA-tRNAs are joined by peptide linkages.

Select one of the following:

Explanation

Question 6 of 32

Genes function (are expressed) only in cells they relate to, when they are needed.

Select one of the following:

Explanation

Question 7 of 32

In eukaryotes, genes are only transcribed if an RNA polymerase enzyme binds to a region of DNA situated close to the gene known as a ___ .

Select one of the following:

Explanation

Question 8 of 32

What are the special features of promoters in eukaryotic chromosomes?

Select one or more of the following:

Explanation

Question 9 of 32

The steps of the expression of a gene begin when the genetic informaiton in DNA is transcribed into a molecule of mRNA by complementary base paring. The RNA polymerase binds to a promoter region (the 'start' signal for transcription) located immediately before the gene.

Select one of the following:

Explanation

Question 10 of 32

Highlight the characteristics that apply to the sense strand and leave the once that apply to the antisense strand blank.

Select one or more of the following:

Explanation

Question 11 of 32

RNA polymerase draws on a pool of free nucleotides.

Select one of the following:

Explanation

Question 12 of 32

As the RNA trand is formed, it falls away from the antisense strand and hydrogen bonds re-form between the two DNA strands. The process continues until a base sequence known as the inhibitor is reached, causing both RNA polymerase and the completed mRNA strand to be freed from the site of the gene.

Select one of the following:

Explanation

Question 13 of 32

The sections of DNA that carry meaningful information are called introns and the intervening lengths f DNA are called exons.

Select one of the following:

Explanation

Question 14 of 32

When a split gene is transcribed into mRNA, the sequence of introns continues to exist exactly as it occurred in the DNA, and so an enzyme catalysed reaction known as ___ removes the introns to shorten the length of mRNA which is now described as mature before it moves out into the cytoplasm.

Select one of the following:

Explanation

Question 15 of 32

The AA activation process by ehich AA are combined with tRNA occurs in the cytoplasm and requires ATP.

Select one of the following:

Explanation

Question 16 of 32

It is this tRNA, once attached to its AA, which facilitates the translation of the three-base sequences of each codon of mRNA into a sequence of AAs in a protein.

Select one of the following:

Explanation

Question 17 of 32

The codon located on one end of the tRNA is complementary to the codon of mRNA that codes for that specific AA.

Select one of the following:

Explanation

Question 18 of 32

An AA is attached to its tRNA by enzyme action specific to that AA, which allows recognition by a specific tRNA activating enzyme which attaches a specific AA to the tRNA and ensure they'r ein the right sequence.

Select one of the following:

Explanation

Question 19 of 32

Translation occurs in the ribosomes which are organelles made up of a large and small subunit which are both composed of ___ and protein. During translation, the mRNAs bind with the ___ subunit where also occur the three sites where the tRNA's interact.

Select one of the following:

Explanation

Question 20 of 32

At the 1st site, codons of the incoming tRNA bind to specific tRNA AAs through their anticodons by complementary base paring.

Select one of the following:

Explanation

Translation occurs in the ribosomes which are organelles made up of a large and small subunit which are both composed of _ and protein. During translation, the mRNAs bind with the _ subunit where also occur the three sites where the tRNA's interact.