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CONGENITAL IMMUNODEFICIENCY
ACQUIRED IMMUNODEFICIENCY
10 WARNING SIGNS of PID (1°)
MOST COMMON PID (1°) ?
RARE?
BACTERIA ASSOCIATED WITH ?
FUNGI associated with ?
PHAGOCYTIC DISORDERS (rare)
(1°)
CGD?
PHAGOCYTIC DISORDERS
(1°)
Congenital Agranulocystosis
PHAGOCYTIC DISORDERS
(1°)
Leukocyte Adhesion Deficiency
T Cell Disorders: (much more common)
Severe Combined Immunodeficiency (SCID)
"Bubble Boy"
T Cell Disorders:
Severe Combined Immunodeficiency (SCID)
Continued. . .
RAG 1/2
Infants
IL2-R defect
T cell disorders:
DiGeorge Syndrome
T CELL disorders
BARE-Lymphocye Syndrome (BLS)
T CELL Disorders
Wiskott-Aldrich Syndorme (WAS)
KEY CONCEPT:
Lymphocyte Phenotype and Molecular Defect??
B CELL Disorders:
Bruton's X-linked A-g-globulinemia
B CELL disorders:
Selective IgA Deficiency
B CELL Disorders
Common Variable Immune Deficiency
(CVID)
SECONDARY (2°) Immunodeficiencies
