Module 2 Set A (Pharmacy)

Descripción

Medicine Test sobre Module 2 Set A (Pharmacy), creado por Bryan Suringa el 06/11/2020.
Bryan Suringa
Test por Bryan Suringa, actualizado hace más de 1 año
Bryan Suringa
Creado por Bryan Suringa hace más de 3 años
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Resumen del Recurso

Pregunta 1

Pregunta
What two enzymes are used to bypass the pyruvate kinase reaction of glycolysis? I. pyruvate carboxylase II. PEP carboxykinase (PEPCK) III. Fructose bisphosphatase IV. Glucose-6-phosphate
Respuesta
  • A. I & II
  • III & IV
  • II & IV
  • II & III

Pregunta 2

Pregunta
Which of the following includes the main goals of Pentose Phosphate Pathway? I. produce ribose-5-phosphate for nucleotide synthesis II. produce NADPH and NADP for oxidoreductive biochemical synthesis III. to interconvert pentoses and hexoses
Respuesta
  • I & II
  • II & III
  • I & III
  • I, II & III

Pregunta 3

Pregunta
Which of the following statements is/are true regarding the secondary structure of nucleic acids? I. Guanine forms base pairs with cytosine via 2 hydrogen bonds II. The B form of the DNA is the most common in biological systems III. The breaking of H-bonds caused by high temperature is called melting
Respuesta
  • I,II & III
  • I & II
  • II & III
  • I & III

Pregunta 4

Pregunta
The phospholipid, phosphatidylinositol 4,5-bisphosphate forms the potent secondary messengers inositol triphosphate & diacylglycerol via what enzyme?
Respuesta
  • Phospholipase A
  • Phospholipase C
  • Phospholipase D
  • Phospholipase B

Pregunta 5

Pregunta
Which of the following is not true regarding the four enzyme complexes of the electron transport chain?
Respuesta
  • Complex I is known as the NADH-CoQ Oxidoreductases
  • Complex II is known as Succinate-CoQ Oxidoreductases
  • Complex III is known as Cytochrome Oxidase
  • Complex IV is known as Cytochrome Oxidase

Pregunta 6

Pregunta
Glucose and mannose are epimers at:
Respuesta
  • Carbon 4
  • Carbon 2
  • Carbon 3
  • Carbon 5

Pregunta 7

Pregunta
One important endogenous molecule for synthetic biotransformation of xenobiotics is glucuronic acid. It is actually the most dominant conjugative biotransformation pathway due to the readily available source of glucose. It is produce from glucose via:
Respuesta
  • Oxidation at carbon 1
  • Oxidation at carbon 2
  • Oxidation at carbon 6
  • Oxidation at carbon 1 & 6

Pregunta 8

Pregunta
Which of the following is not true about protein structure determination?
Respuesta
  • NMR is the only means of determining protein structure
  • Protein are difficult to crystallize, a disadvantage of x-ray crystallography
  • An advantage of the use of the NMR is that proteins analyzed are in their natural state
  • Large and very complex proteins can only be analyzed by x-ray crystallography

Pregunta 9

Pregunta
Tertiary structures of proteins are primarily stabilized by I. H-bonds II. Hydrophobic interactions III. Ionic bonds IV. Disulfide bonds
Respuesta
  • I, II, III & IV
  • I, II& IV
  • I,III & IV
  • I & III

Pregunta 10

Pregunta
In an uncompetitive inhibition of enzymatic action :
Respuesta
  • Inhibitor binds either to the free enzyme or the enzyme substrate complex
  • Lineweaver-Burk plots of the enzyme alone (control) & the enzyme + inhibitor are parallel to each other
  • The apparent Km is raised
  • The Vmax is unaffected

Pregunta 11

Pregunta
Which biomolecule is not considered a biopolymer?
Respuesta
  • Proteins
  • Lipids
  • Nucleic acids
  • Carbohydrates

Pregunta 12

Pregunta
It is regarded as the universal biological energy currency
Respuesta
  • Adenosine triphosphate
  • Guanosine triphosphate
  • Uncouplers
  • Calories

Pregunta 13

Pregunta
This is the final electron acceptor of the electron transport chain in aerobic respiration.
Respuesta
  • Complex I
  • Complex I&II
  • Nitrate
  • Oxygen

Pregunta 14

Pregunta
The most accepted hypothesis regarding oxidative phosphorylation is
Respuesta
  • Chemical coupling
  • Conformational coupling
  • Chemiosmotic hypothesis
  • Lock and Key Theory

Pregunta 15

Pregunta
This is a quantitative study of the energy transformations in the living cell
Respuesta
  • Bioenergetics
  • Thermodynamics
  • Proteomics
  • Metabolomics

Pregunta 16

Pregunta
Which of the following hormones promotes rapid glycogenolysis in both liver and muscle
Respuesta
  • ACTH
  • Glutamine
  • Epinephrine
  • Prolactin

Pregunta 17

Pregunta
Which vitamin can be used in the management of hyperlipidemia?
Respuesta
  • Thiamine
  • Riboflavin
  • Niacin
  • Pantothenic acid

Pregunta 18

Pregunta
Bond between 2 amino acids
Respuesta
  • Glycosidic bond
  • N-glycosyl linkage
  • Peptide Bond
  • Hydrogen bond

Pregunta 19

Pregunta
Beta oxidation of fatty acids in eukaryotic cells occurs in the
Respuesta
  • Cytosol
  • Mitochondria
  • Endoplasmic reticulum
  • Ribosomes

Pregunta 20

Pregunta
The pentose phosphate pathway (aka HMP Shunt) occurs in the ________ of the liver, muscle and kidney.
Respuesta
  • cytosol
  • mitochondria
  • endoplasmic reticulum
  • ribosomes

Pregunta 21

Pregunta
The isoelectric point is the
Respuesta
  • pH where the alpha amino acid exist in its negatively charged form
  • pH wherein the amino acid exist in zwitterionic form
  • Temperature at which the amino acid denatures
  • Pressure at which the amino acid hydrolyzes

Pregunta 22

Pregunta
This is the only optically inactive amino acid
Respuesta
  • methionine
  • Lysine
  • Citrulline
  • glycine

Pregunta 23

Pregunta
This level of protein structure is applicable only to those have several subunits
Respuesta
  • Primary
  • Secondary
  • Tertiary
  • Quaternary

Pregunta 24

Pregunta
Arginine is the only metabolite of the urea cycle that does not accumulate because
Respuesta
  • It is readily excreted
  • It is used up by the body for protein synthesis
  • There is no known deficiency in the enzyme that catabolizes it
  • It can be acquired from food

Pregunta 25

Pregunta
This is the genetic condition characterized by deficiency of the enzyme branched chain alpha-keto acid dehydrogenase
Respuesta
  • Maple syrup disease
  • Hartnup disease
  • Kwashiorkor
  • Marasmus

Pregunta 26

Pregunta
These are compounds related to cerebrosides that contain sphingosine, long chain fatty acids, hexoses (usually galactose or glucose) and neuraminic acid
Respuesta
  • cephalins
  • gangliosides
  • cytolipins
  • lecithins

Pregunta 27

Pregunta
This enzyme catalyzes the conversion fructose-6-P to fructose-1,6-bis-P
Respuesta
  • hexokinase
  • pyruvate kinase
  • PFK-1
  • Fructose bisphosphatase

Pregunta 28

Pregunta
Which of the following is called transamination?
Respuesta
  • Conversion of amino acids to hydroxyl groups
  • Conversion of amino acids to keto acids
  • Loss of ammonia from amino acids
  • Formation of ammonium salts from ammonia

Pregunta 29

Pregunta
The sugar involved in the DNA
Respuesta
  • ribose
  • pentose
  • deoxyribose
  • xylose

Pregunta 30

Pregunta
This is the reason why blood AB is considered as the universal recipient.
Respuesta
  • It is the most common among the ABO blood types
  • Blood type AB has neither A nor B substances
  • Blood type AB has no anti-A or anti-B antibodies
  • All of the above

Pregunta 31

Pregunta
Which one is true regarding the structures of lipids?
Respuesta
  • Eicosapentaenoic acid is a saturated fatty acid
  • They may exist as esters of cholesterol when they are enclosed in very low density
  • Linoleic acid is an omega-3 fatty acid
  • Capric acid contains 12 carbons

Pregunta 32

Pregunta
This is the product of basic hydrolysis of fats and oils
Respuesta
  • fatty acid
  • triacylglycerol
  • soap
  • detergent

Pregunta 33

Pregunta
The group of lipids that is considered amphipathic
Respuesta
  • sterols
  • fatty acids
  • trans-fatty acids
  • phospholipids

Pregunta 34

Pregunta
Which properly describes a liposome?
Respuesta
  • It is a hollow sphere-like structure composed of a lipid bilayer enclosing an aqueous cavity
  • It is a lipid structure wherein the hydrophobic chains of the fatty acids are sequestered at the core of the sphere with virtually no water in the hydrophobic interior
  • It is a lipoprotein integrated in the phospholipid bilayer of the cell membranes
  • It is a hollow sphere-like structure composed of a lipid monolayer enclosing a hydrophobic cavity

Pregunta 35

Pregunta
It is the building block of essential fatty acids
Respuesta
  • Malonyl CoA
  • Phosphoribosyl pyrophosphate
  • Acetyl CoA
  • HMG CoA

Pregunta 36

Pregunta
The digestion of carbohydrates begins in the________.
Respuesta
  • mouth
  • stomach
  • small intestine
  • duodenum

Pregunta 37

Pregunta
Cellular elements of the blood devoid of nucleus
Respuesta
  • RBC
  • WBC
  • thrombocytes
  • all of the above

Pregunta 38

Pregunta
Conjugated proteins which are a combination of amino acids and carbohydrates
Respuesta
  • nucleoproteins
  • glycoproteins
  • phosphoproteins
  • chromoproteins

Pregunta 39

Pregunta
Glucose is normally absent in the urine because kidneys normally completely reabsorb all glucose. Which of the following is true?
Respuesta
  • Glucosuria confirms diabetes mellitus
  • Glucosuria necessarily means hyperglycemia
  • Glucosuria is solely attributed to insulin problem
  • Glucosuria may occur in other disease states

Pregunta 40

Pregunta
Wernicke-Korsakoff syndrome which can cause acute confusion, ataxia and ophthalmoplegia, can be treated with which of the following?
Respuesta
  • riboflavin
  • ascorbic acid
  • thiamine
  • pantothenic acid

Pregunta 41

Pregunta
This is the major excretory product of purine nucleotides
Respuesta
  • inosine monophosphate
  • uric acid
  • methylmalonyl CoA
  • tetrahydrofolate

Pregunta 42

Pregunta
This is the phenomena of renaturation of nucleic acid after it has been subjected to high temperature and then to room temperature
Respuesta
  • Hydrolysis
  • Polymerase chain reaction
  • annealing
  • hybridization

Pregunta 43

Pregunta
This is the base sequence for the start codon
Respuesta
  • UAG
  • UGA
  • AUG
  • UAA

Pregunta 44

Pregunta
This feature of bacterial cells confers selectivity of antibacterial agents targeting protein synthesis to the bacteria and not to the host cell.
Respuesta
  • mRNA
  • 40s ribosomal subunit
  • lack of cell wall
  • 30s ribosomal subunit

Pregunta 45

Pregunta
This is also known as the RNA-directed DNA polymerase
Respuesta
  • RNA polymerase II
  • Reverse transcriptase
  • DNA polymerase alpha
  • DNA polymerase II

Pregunta 46

Pregunta
What essential amino acid is used in the synthesis of niacin?
Respuesta
  • Tyrosine
  • Methionine
  • tryptophan
  • Phenylalanine

Pregunta 47

Pregunta
The cellular particles are often referred to by their sedimentation coefficient value, for example 70s ribosomes that are expressed in terms of 10 -13 seconds. The abbreviation “s” stands for
Respuesta
  • subunit
  • Seconds
  • Svedberg
  • None of the above

Pregunta 48

Pregunta
The best known building blocks of RNA and DNA are
Respuesta
  • purines
  • pyrimidines
  • fatty acids
  • a and b

Pregunta 49

Pregunta
The following are pathological constituents of urine, except:
Respuesta
  • glucose
  • albumin
  • creatinine
  • blood

Pregunta 50

Pregunta
Glucose and galactose differ only in the configuration of their hydroxyl group at carbon 4. Glucose and galactose are:
Respuesta
  • diastereomers
  • enantiomers
  • epimers
  • anomers

Pregunta 51

Pregunta
The chemical representation shows the most stable conformation of hexoaldopyranoses
Respuesta
  • Fischer projection
  • Boat conformation
  • Haworth Formula
  • Chair conformation

Pregunta 52

Pregunta
These are vegetables or animal drugs that consist of natural substances that have undergone only the process of collection and drying
Respuesta
  • natural substances
  • crude drugs
  • Extractives
  • Derivatives

Pregunta 53

Pregunta
What do you call plants growing in their native countries?
Respuesta
  • indigenous
  • naturalized
  • cultivated
  • local

Pregunta 54

Pregunta
What is used to treat cascara sagrada extract to reduce its bitter taste?
Respuesta
  • Magnesium oxide
  • Calcium carbonate
  • Simple syrup
  • Talc

Pregunta 55

Pregunta
What type of saponin glycosides are derivatives of steroids with spiroketal side chains?
Respuesta
  • Acid saponins
  • Alkaline saponins
  • Neutral saponins
  • None of the above

Pregunta 56

Pregunta
This is the final step in the preparation of drugs for the commercial market, consisting of the removal of extraneous matter.
Respuesta
  • Packaging
  • Preservation
  • Garbling
  • Harvesting

Pregunta 57

Pregunta
Natural relationship existing among plants and among animals
Respuesta
  • taxonomy
  • morphology
  • phylogeny
  • Systematics

Pregunta 58

Pregunta
8. In the preservation of crude drugs, this method is the simplest in preventing insect attacks and other form of destruction
Respuesta
  • Exposure of the drug to a temperature of 65°C
  • Use of methyl chloride
  • adding a few drops of benzene
  • AOTA

Pregunta 59

Pregunta
This refers to the evaluation by means of the sense organs and includes the macroscopic appearance of the drug, odor, taste, sound upon fracture and feel to the touch
Respuesta
  • Physical Analysis
  • Chemical Analysis
  • Proximate Analysis
  • Organoleptic Analysis

Pregunta 60

Pregunta
The first commercial application of the technique in pharmaco-biotechnology was made by Eli Lilly Company. Using the non-disease producing strain of E.coli, this company produced the hormone
Respuesta
  • Glucagon
  • somatostatin
  • insulin
  • somatomedin

Pregunta 61

Pregunta
Which of the following may influence the secondary constituents of plant drugs?
Respuesta
  • genetic composition
  • ontogeny
  • environment
  • all of the above

Pregunta 62

Pregunta
These are products of natural origin many of which without therapeutic effect used by the laity in the self-treatment of diseases.
Respuesta
  • Health Foods
  • Crude drugs
  • Extracts
  • AOTA

Pregunta 63

Pregunta
Which of the following statement/s is/are true? I. Gums and mucilages are carbohydrates II. Streptomycin is a carbohydrate III. The concentration of secondary metabolites increases with age IV. Biogenesis refers to the study of biochemical pathways leading to the formation of secondary constituents used as drugs
Respuesta
  • I, II and IV
  • I, II and III
  • I and III
  • III Only

Pregunta 64

Pregunta
Which of the following pairs is correct?
Respuesta
  • reserpine-hypotensive
  • sambong-stomachic
  • bayabas-diuretic
  • lagundi-analgesic

Pregunta 65

Pregunta
Which of the following statements is/are correct?
Respuesta
  • Synthetic Camphor is levorotatory
  • Natural Camphor is dextrorotatory
  • Both natural and semisynthetic camphor are racemic
  • NOTA

Pregunta 66

Pregunta
Give the proper sequence of the following processes in the preparation of natural drugs. I. Garbling II. Collection III. Drying IV. Harvesting V. Packaging
Respuesta
  • III-I-IV-II-V
  • II-IV-III-I-V
  • II-I-IV-V-III
  • IV-I-III-V-II

Pregunta 67

Pregunta
This classification of drugs considers the natural relationship or phylogeny among plants and animals.
Respuesta
  • taxonomic
  • morphologic
  • zoologic
  • zoologic and taxonomic

Pregunta 68

Pregunta
The source of bassorin
Respuesta
  • acacia
  • Karaya
  • gum
  • Tragacanth

Pregunta 69

Pregunta
Mannitol is used pharmacologically as a/an
Respuesta
  • humectant
  • osmotic diuretic
  • anti-infective
  • urologic irritant

Pregunta 70

Pregunta
Which of the following is/are homoglycan(s)?
Respuesta
  • starch
  • starch and inulin
  • inulin
  • gums

Pregunta 71

Pregunta
The milk left after separation of the cream
Respuesta
  • cheese
  • condensed milk
  • skimmed milk
  • buttermilk

Pregunta 72

Pregunta
Fermentation product from molasses
Respuesta
  • wine
  • whiskey
  • rum
  • brandy

Pregunta 73

Pregunta
It is also known as the carob pulp or St. John's Bread
Respuesta
  • locust bean
  • Xanthan
  • guar
  • acacia

Pregunta 74

Pregunta
It tastes approximately half as sweet as sucrose, and has humectant properties which makes it a useful ingredient in toothpastes, chewing gums, and dietetic products.
Respuesta
  • mannitol
  • fructose
  • dulcitol
  • sorbitol

Pregunta 75

Pregunta
A pharmaceutical aid in the preparation of collodion and flexible collodion.
Respuesta
  • methylcellulose phthalate
  • soluble guncotton
  • powdered cellulose
  • cellulose acetate

Pregunta 76

Pregunta
Gum usually used as a substitute for acacia
Respuesta
  • ghatti
  • tragacanth
  • karaya
  • algin

Pregunta 77

Pregunta
It is also referred to as Japanese Isinglass, and is extensively used as a gel in bacteriologic culture media.
Respuesta
  • carrageenan
  • agar
  • chondrus
  • cydonium

Pregunta 78

Pregunta
Powdered cellulose is the purified, mechanically disintegrated cellulose used as a self-binding tablet diluent and disintegrating agent. Which of the following statements regarding powdered cellulose is correct? A) The purity of cellulose is defined by its solubility in hydrochloric acid. B) The cellulose remaining insoluble is termed a-cellulose. C) The greater the quantity of a-cellulose present, the higher the quality of the material.
Respuesta
  • B and C only
  • A and B only
  • B only
  • NOTA

Pregunta 79

Pregunta
The most important monosaccharides found in plants
Respuesta
  • hexoses
  • pentoses
  • heptoses
  • octoses

Pregunta 80

Pregunta
Which of the following is a source of sucrose?
Respuesta
  • Acer saccharum
  • Bos taurus
  • Prunus cerasus
  • Sorbus aucuparia

Pregunta 81

Pregunta
Which of the following statements is/are true?
Respuesta
  • Dextrose is a-(L)-glucopyranose
  • Dextrose is obtained from controlled enzymatic hydrolysis of starch
  • Dextrose can only be given PO and IV
  • AOTA

Pregunta 82

Pregunta
This is a product obtained from the incomplete hydrolysis of starch. It is a colorless or yellowish, thick syrupy liquid that is nearly odorless and tastes sweet.
Respuesta
  • liquid dextrose
  • liquid sucrose
  • liquid dextrin
  • liquid glucose

Pregunta 83

Pregunta
Which of the following pairs is correct?
Respuesta
  • Ferrous gluconate - hematinic
  • Xylose-laxative
  • Lactulose-diagnostic aid
  • AOTA

Pregunta 84

Pregunta
Which of the following statements refers to fructose? A) from honey B) obtained from the inversion of aqueous solutions of sucrose C) upon hydrolysis, sucrose yields a higher fructose than dextrose content
Respuesta
  • A and B only
  • B and C only
  • C only
  • B only

Pregunta 85

Pregunta
In milk processing, the liquid separated from coagulum is known as
Respuesta
  • condensed milk
  • butter
  • buttermilk
  • whey

Pregunta 86

Pregunta
This is a pentose also known as wood sugar, which is obtained by boiling corn cobs, straw, or similar materials with dilute acid to hydrolyze the polymer.
Respuesta
  • ribose
  • xylose
  • erythrose
  • trehalose

Pregunta 87

Pregunta
Which of the following statements concerning lactulose is true?
Respuesta
  • Natural sugar prepared by acidic rearrangement of lactose
  • Trisaccharide
  • Well absorbed
  • Bacteria in the colon metabolize it to acetic acid and lactic acid

Pregunta 88

Pregunta
Xylose is used as a /an
Respuesta
  • diuretic
  • pharmaceutical excipient
  • binder
  • diagnostic aid

Pregunta 89

Pregunta
In glycolysis, what enzyme is involved in the conversion of 3 phosphoglyceraldehyde to 1,3-Bisphosphoglyceric acid?
Respuesta
  • kinase
  • aldolase
  • dehydrogenase
  • isomerase

Pregunta 90

Pregunta
Aside from thiamine pyrophosphate, what coenzyme/cofactor aids in the oxidative decarboxylation of pyruvic acid with pyruvic acid dehydrogenase?
Respuesta
  • NAD
  • Lipoic Acid
  • FAD
  • Mg

Pregunta 91

Pregunta
Glucose-6-PO, is converted to ____ upon the action of phosphohexose isomerase.
Respuesta
  • Glucose-1-Phosphate
  • Fructose-6-Phosphate
  • Fructose-1.6-Diphosphate
  • Dihydroxyacetone phosphate

Pregunta 92

Pregunta
Pyruvic acid, upon the action of pyruvic acid decarboxylase yields ____
Respuesta
  • ethanol
  • lactic acid
  • methanol
  • acetaldehyde

Pregunta 93

Pregunta
Alcohol dehydrogenase acts on acetaldehyde to yield ____
Respuesta
  • lactic acid
  • pyruvic acid
  • ethanol
  • AOTA

Pregunta 94

Pregunta
Which tricarboxylic acid was first isolated by scheele in 1784
Respuesta
  • citric acid
  • Tartaric acid
  • lactic acid
  • fumaric acid

Pregunta 95

Pregunta
This acid is a byproduct of wine
Respuesta
  • citric acid
  • tartaric acid
  • lactic acid
  • fumaric acid

Pregunta 96

Pregunta
This acid used as an acidulant especially in feeding formulas
Respuesta
  • Citric acid
  • tartaric acid
  • lactic acid
  • fumaric acid

Pregunta 97

Pregunta
Which of the following may be produced from the process of distillation?
Respuesta
  • whiskey
  • rum
  • brandy
  • AOTA

Pregunta 98

Pregunta
Which of the following statement/s is/are true?
Respuesta
  • Wine is sometimes used medically as a mild stimulant and tonic
  • Brandy is used as CNS stimulant
  • Whiskey is used as CNS stimulant
  • AOTA

Pregunta 99

Pregunta
Which of the following is obtained from Fraxinus ornus I. (Fam. Oleaceae), and is used for its laxative properties?
Respuesta
  • glucitol
  • mannitol
  • Sorbitol
  • Lactose

Pregunta 100

Pregunta
What is the usual diagnostic dose of mannitol injection?
Respuesta
  • 200 mg/kg body weight in a 15-25% solution IV in 3-5 minutes
  • 50-100g daily in a 5-25% solution by IV infusion
  • 200 g/kg body weight in a 15-25% solution in 3-5 minutes
  • 50-100 kg daily in a 5-25% solution by IV infusion
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