The HUMAN GENOME

Descripción

Very important. Much amaze. Wow
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Resumen del Recurso

Pregunta 1

Pregunta
The Human genome is made up of approx 30,000 genes (in both mitochondrial and nuclear DNA
Respuesta
  • True
  • False

Pregunta 2

Pregunta
How do genes code more than one protein?
Respuesta
  • Reversed transcription
  • Gene modification
  • Differential splicing

Pregunta 3

Pregunta
What is the most versitile human gene?
Respuesta
  • The Slo gene
  • The Pap gene
  • The Hr4 gene

Pregunta 4

Pregunta
The human slo gene can make up to 500 different mRNA's and works in sound regulation
Respuesta
  • True
  • False

Pregunta 5

Pregunta
RNA cannot be edited after transcription
Respuesta
  • True
  • False

Pregunta 6

Pregunta
What is a common method of altering RNA?
Respuesta
  • Degrading cytosine to uracil
  • Degrading thymine to uracil
  • Degrading adenine to uracil

Pregunta 7

Pregunta
Approx 20% of cytosine is methylated
Respuesta
  • True
  • False

Pregunta 8

Pregunta
Cytosine methylation is restricted to where?
Respuesta
  • C's immediately 5' of guanidine
  • C's immediately 5' of adenine
  • C's immediately 3' of guanidine
  • C's immediately 3' of adenine

Pregunta 9

Pregunta
Methylated cytosine can spontaneously deanimate to thymine
Respuesta
  • True
  • False

Pregunta 10

Pregunta
Match the word to it's definition- where methylation is done upstream of a gene in order to pack it around the nucleosome and silence it
Respuesta
  • De-novo methylation
  • Maintentence Methylation

Pregunta 11

Pregunta
Maintanence methylation- added to newly synthesised DNA opposite methylated groups on the parent strand
Respuesta
  • True
  • False

Pregunta 12

Pregunta
Clusters in the human genome are the same as in the bacterial genome
Respuesta
  • True
  • False

Pregunta 13

Pregunta
What is a multigene family?
Respuesta
  • Where related genes of a similar function are found together
  • Where related genes of different functions are found together
  • Related genes with similar functions

Pregunta 14

Pregunta
Gene families are orthologues of each other
Respuesta
  • True
  • False

Pregunta 15

Pregunta
What is a pseudogene?
Respuesta
  • An inactive gene due to faulty (partial) replication of the original
  • A mutated gene that has become non-functional
  • Slowly more mutations accumulate

Pregunta 16

Pregunta
What is the difference between a pseudogene and a processed pseudogene?
Respuesta
  • The latter has no introns or promoter
  • The former contains no introns or promoter
  • The latter can be used to create mRNA (though it's non functional)

Pregunta 17

Pregunta
Processed pseudogenes are throught to be caused by the re-integration of siRNA into the genome
Respuesta
  • True
  • False

Pregunta 18

Pregunta
Gene fragments are sections that look like incomplete genes
Respuesta
  • True
  • False

Pregunta 19

Pregunta
Assuming the squares are all repeated units, what is the image an example of?
Respuesta
  • Iterspersed Repeated Intergenic DNA
  • Gene Clusters
  • Introns

Pregunta 20

Pregunta
Which of the following is not an Interpersed Repeated Intergenic DNA?
Respuesta
  • LINES
  • SINES
  • DNA transposons
  • MINES

Pregunta 21

Pregunta
Interspersed Repeating Intergenic DNA are DNA sections that replicate themselves as they move around the genome.
Respuesta
  • True
  • False

Pregunta 22

Pregunta
LTR's, LINE's and SINES's are transposed around the genome, how?
Respuesta
  • RNA
  • DNA
  • Proteins

Pregunta 23

Pregunta
DNA transposons also have an RNA intermediate
Respuesta
  • True
  • False

Pregunta 24

Pregunta
Satellites, Minisatellites and Microsatellites are all examples of what?
Respuesta
  • Tandemly repeated extragenic DNA
  • Interspersed Replicating Integrated Elements
  • Interspersed Repeating Intergenic elements

Pregunta 25

Pregunta
Microsatellites are caused by replication slippage
Respuesta
  • True
  • False

Pregunta 26

Pregunta
Tandemly Repeating Extragenic DNA is useful for what?
Respuesta
  • Splicing
  • DNA fingerprinting
  • Genome mapping
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